Results 71 to 80 of about 2,205,306 (373)
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Revista Latino-Americana de Enfermagem, 2021 Objective: to evaluate the complications of percutaneous renal biopsy based on outcomes and clinical indicators of the Nursing Outcomes Classification. Method: a prospective longitudinal study.
Magáli Costa Oliveira +5 more
doaj +3 more sources
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
FEBS Open Bio, EarlyView.Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian +6 more
wiley +1 more source
Impaired microvascular circulation in distant organs following renal ischemia.
PLoS ONE, 2023 Mortality in acute kidney injury (AKI) patients remains very high, although very important advances in understanding the pathophysiology and in diagnosis and supportive care have been made. Most commonly, adverse outcomes are related to extra-renal organ
Jesus H Dominguez, Danhui Xie, K J Kelly
doaj +1 more source
Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity
FEBS Open Bio, EarlyView.This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang +6 more
wiley +1 more source
Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024
FEBS Open Bio, EarlyView.The 2nd MObility for Vesicle research in Europe (MOVE) Symposium in Belgrade brought over 280 attendees from 28 countries to advance extracellular vesicle (EV) research. Featuring keynotes, presentations, and industry sessions, it covered EV biogenesis, biomarkers, therapies, and manufacturing.
Dorival Mendes Rodrigues‐Junior +5 more
wiley +1 more source
The effects of short-term omission of daily medication on the pathophysiology of heart failure [PDF]
, 2016 Aims Pharmacological therapies for heart failure (HF) aim to improve congestion, symptoms, and prognosis. Failing to take medication is a potential cause of worsening HF.
Abraham +31 more
core +4 more sources
FEBS Open Bio, EarlyView.Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp +13 more
wiley +1 more source
RENAL PORTAL CIRCULATION IN CHICKENS
The Japanese Journal of Veterinary Science, 1973 腎門脈弁におよぼす薬物の影響をinvivoで研究した報告は皆無であるばかりでなく,血流を直接的方法で測定した報告もない.鶏において,とくに尾腸間膜静脈(CMV)の血流量とその方向を決定することは,これまでの血流循環系分野の最大の関心事の一つであった.従って,著者らは,実験材料として白色レグホーンの雄を選び,麻酔下で電磁血流計を用いて,CMVの血流の方向を調べ,CMVおよび後大静脈(IVC)の血流量を測定した.また同時に心拍数および頚動脈血圧も測定した.10μg/kgのnorepinephrinc(NE)ならびに0.1mg/kgのacctylcholine(Ach)を翼下静脈に注射して,血流量およびCMVの血流方向の変化から,腎門脈弁に対する薬物の作用を研究することが,本実験の目的である ...
Kiyoshi Shimada, Paul D Sturkie
openaire +4 more sources
Small Vessel Disease in the Heart and Brain: Current Knowledge, Unmet Therapeutic Need and Future Directions [PDF]
, 2019 No abstract ...
Berry, C +6 more
core +2 more sources