Results 71 to 80 of about 2,167,615 (375)

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification

FEBS Open Bio, EarlyView.
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski, Irene Cortijo, Shruti Bhargava, Bernard Jover, Fabrice Raynaud, Juliana H Boukhaled, Anne‐Dominique Lajoix, Vera Jankowski, Joachim Jankowski, Magali Cordaillat‐Simmons, Àngel Argilés, Nathalie Gayrard, Flore Duranton, Jonas Laget   +13 more
wiley   +1 more source

Successful revascularization of the kidney: Case reports [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2004
Three cases of successful kidney revascularization and recovery of renal function are presented in this study. In all three cases, renal failure and renovascular hypertension were caused by renal artery occlusion associated with aortic aneurysm (two ...
Davidović Lazar B., Sinđelić Radomir B., Stanojević Mirjana Lj., Kuzmanović Ilija B., Čolić Momčilo M., Perišić Mirjana D., Pejkić Siniša U.   +6 more
doaj   +1 more source

Neuraxial modulation for treatment of VT storm. [PDF]

, 2014
In the hyperadrenergic state of VT storm where shocks are psychologically and physiologically traumatizing, suppression of sympathetic outflow from the organ level of the heart up to higher braincenters plays a significant role in reducing the propensity
Shivkumar, Kalyanam, Tung, Roderick
core   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

PROXIMAL EXTENSION OF JUXTA-RENAL AORTIC THROMBOSIS: AN UNDERESTIMATED COMPLICATION?

Angiologia e Cirurgia Vascular, 2021
Aorto-iliac occlusive disease sometimes extends proximally with involvement of the renal arteries and visceral aorta, with loss of renal functional mass and intestinal ischemia. In this article we report the case of a patient presenting with progressive
Mickael Henriques, Augusto Ministro, Emanuel Silva, Vanda Pinto, João Rato, Luís Mendes Pedro   +5 more
doaj   +1 more source

Alkaline phosphatases in the complex chronic kidney disease-mineral and bone disorders [PDF]

, 2018
Alkaline phosphatases (APs) remove the phosphate (dephosphorylation) needed in multiple metabolic processes (from many molecules such as proteins, nucleotides, or pyrophosphate). Therefore, APs are important for bone mineralization but paradoxically they
Aguilar, Armando, Benito, Silvia, Bover, Jordi, Cozzolino, Mario, Dasilva, Iara, López-Báez, Víctor, Mazzaferro, Sandro, Ramos, Alejandra, Ureña, Pablo   +8 more
core   +1 more source

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

FEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang, Yuan Cao, Jing Du, Ying Zhang, Junxia Wang, Ying Yuan, Lianqing Sun   +6 more
wiley   +1 more source

RENAL PORTAL CIRCULATION IN CHICKENS

The Japanese Journal of Veterinary Science, 1973
腎門脈弁におよぼす薬物の影響をinvivoで研究した報告は皆無であるばかりでなく,血流を直接的方法で測定した報告もない.鶏において,とくに尾腸間膜静脈(CMV)の血流量とその方向を決定することは,これまでの血流循環系分野の最大の関心事の一つであった.従って,著者らは,実験材料として白色レグホーンの雄を選び,麻酔下で電磁血流計を用いて,CMVの血流の方向を調べ,CMVおよび後大静脈(IVC)の血流量を測定した.また同時に心拍数および頚動脈血圧も測定した.10μg/kgのnorepinephrinc(NE)ならびに0.1mg/kgのacctylcholine(Ach)を翼下静脈に注射して,血流量およびCMVの血流方向の変化から,腎門脈弁に対する薬物の作用を研究することが,本実験の目的である ...
Kiyoshi Shimada, Paul D Sturkie
openaire   +4 more sources

Protective importance of the myogenic response in the renal circulation.

HYPERTENSION, 2009
Primary essential hypertension is second only to diabetic nephropathy as a etiology for end-stage renal disease.1 In addition, coexistent/superimposed hypertension plays a major role in the progression of most forms of chronic kidney disease (CKD ...
A. Bidani, K. Griffin, G. Williamson, Xuemei Wang, R. Loutzenhiser   +4 more
semanticscholar   +1 more source