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Severe hypertension, resistant to conventional antihypertensive medications, is associated with major adverse cardiovascular and cerebrovascular events and renal insufficiency. Renal sympathetic nerve over-activity frequently accompanies essential hypertension.
Todd, Drexel +3 more
+7 more sources
Renal Denervation in Hypertension
The column in this issue is supplied by Drs. Benjamin Lee, MD, and Usman Ansari, DO. Dr. Lee is an assistant professor of clinical medicine at the Houston Methodist Institute for Academic Medicine and Weill Cornell Medical College. After earning his medical degree at Harvard Medical School, Dr.
Usman S, Ansari, Benjamin J, Lee
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Renal Denervation and Hypertension [PDF]
Essential hypertension remains one of the biggest challenges in medicine with an enormous impact on both individual and society levels. With the exception of relatively rare monogenetic forms of hypertension, there is now general agreement that the condition is multifactorial in nature and hence requires therapeutic approaches targeting several aspects
Markus P, Schlaich +3 more
openaire +2 more sources
Renal Denervation for Resistant Hypertension [PDF]
Resistant hypertension is highly prevalent among the general hypertensive population and the clinical management of this condition remains problematic. Different approaches, including a more intensified antihypertensive therapy, lifestyle modifications, or both, have largely failed to improve patients' outcomes and to reduce cardiovascular and renal ...
Coppolino G +3 more
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Renal Denervation for Resistant Hypertension [PDF]
Renal denervation as a treatment for hypertension (HTN) has been shown to be effective as a surgical procedure. Over the past 10 years, an endovascular approach to replicate the results of surgical splanchnicectomy has been investigated to replace this surgical procedure with a less invasive procedure with lower morbidity.
Reilly, John P., White, Christopher J.
openaire +4 more sources
The Asia Renal Denervation Consortium consensus conference of Asian physicians actively performing renal denervation (RDN) was recently convened to share up-to-date information and regional perspectives, with the goal of consensus on RDN in Asia. First- and second-generation trials of RDN have demonstrated the efficacy and safety of this treatment ...
Kario, Kazuomi +10 more
openaire +3 more sources
Device-based approaches for renal nerve ablation for hypertension and beyond
Animal and human studies have demonstrated that chronic activation of renal sympathetic nerves is critical in the pathogenesis and perpetuation of treatment-resistant hypertension.
Alicia Ann Thorp +2 more
doaj +1 more source
Mentor: Irving H. Zucker Program: Anesthesiology Background & Objectives: The sympathetic nervous system is a master regulator of homeostasis, and sympathetic dysfunction is implicated in the pathophysiology of cardiovascular, renal, and neurological ...
Peter Ricci Pellegrino +4 more
doaj +1 more source
Hypertension is the most prevalent cardiovascular risk factor. Despite pharmacological treatment, a high percentage of patients do not achieve an adequate blood pressure control.
Oriol Rodríguez-Leor +13 more
doaj +1 more source
Animal model evaluation of a novel renal denervation system for future laparoscopic treatment of resistant hypertension [PDF]
Purpose: Although percutaneous catheter-based ablation of renal sympathetic nerve fibers has been used in the treatment of patients with resistant hypertension, a recent phase III study did not confirm its efficacy.
Won Hoon Song +5 more
doaj +1 more source

