Results 81 to 90 of about 653,483 (216)

Neurocardiac crosstalk in inherited cardiac arrhythmias and cardiomyopathy

The Journal of Physiology, EarlyView.
Abstract figure legend In inherited cardiac arrhythmias and cardiomyopathy, arrhythmias are typically triggered by autonomic nervous system activity. Genetic mutations linked to these conditions cause pro‐arrhythmic alterations in both cardiomyocytes and neurons, with their pathophysiological crosstalk likely amplifying the manifestation of the disease.
Carol Ann Remme, Molly O'Reilly
wiley   +1 more source

Long-term effectiveness of radiofrequency renal denervation in patients with resistant arterial hypertension (10-year follow-up results)

, 2023
The aim – to determine the long-term efficacy and safety of renal denervation (RDN) at 10-year follow-up. Materials and methods. We selected 1146 patients with resistant arterial hypertension (RAH) who received 3 or more antihypertensive drugs.
O.O. Torbas, G.F. Prymak, Yu.M. Sirenko, O.L. Rekovets, S.M. Kushnir   +4 more
core   +1 more source

Adaptations of glucagon‐like peptide‐1 receptor agonist‐induced weight loss, drivers of weight regain and future directions of therapeutics

The Journal of Physiology, EarlyView.
Abstract figure legend During GLP‐1RA treatment reduced appetite and energy intake, delayed gastric emptying, decreased visceral fat mass and improved glycaemic control contribute to weight loss. After treatment cessation these benefits are partially or completely reversed, resulting in weight regain, accompanied by increased appetite and energy intake,
Camille E. M. Piguet, Rosie Nucci, Jacqueline L. Beaudry   +2 more
wiley   +1 more source

The Effects of Angiotensin Receptor Neprilysin Inhibitor on Endoplasmic Reticulum Stress in Doxorubicin‐Mediated Cardiomyopathy‐Associated Heart Failure Model in Rats

Journal of Applied Toxicology, Volume 46, Issue 12, Page 4646-4655, December 2026.
ABSTRACT One of the most serious complications associated with the use of the chemotherapeutic agent doxorubicin (DOX) is cardiomyopathy. Although cardioprotective drugs such as angiotensin receptor‐neprilysin inhibitors (ARNI) are used to prevent cardiomyopathy in DOX patients, no studies have reported the relationship between ARNI and endoplasmic ...
Mert Unvan, Meryem İlkay Karagül, Hatice Oruç Demirbağ, Ebru Balli   +3 more
wiley   +1 more source

Adherence to Antihypertensive Medication in Treatment‐Resistant Hypertension Undergoing Renal Denervation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundAdherence to medication has been repeatedly proposed to represent a major cause of treatment‐resistant hypertension (TRH); however, treatment decisions such as treating TRH with renal denervation depend on accurate judgment of adherence.
Roland E. Schmieder, Christian Ott, Axel Schmid, Stefanie Friedrich, Iris Kistner, Tilmann Ditting, Roland Veelken, Michael Uder, Stefan W. Toennes   +8 more
doaj   +1 more source

Renal denervation: Still more questions than answers

, 2014
The paper describes the clinical relevance of renal denervation in ...
BRUNO, ROSA MARIA, TADDEI, STEFANO, Bruno Rosa Maria, Taddei Stefano   +3 more
core   +1 more source

Renal denervation in an animal model of diabetes and hypertension: Impact on the autonomic nervous system and nephropathy

Cardiovascular Diabetology, 2011
Background The effects of renal denervation on cardiovascular reflexes and markers of nephropathy in diabetic-hypertensive rats have not yet been explored.
Machado Ubiratan F, Okamoto Maristela, Souza Martina S, Azambuja Felipe, Leguisamo Natalia M, Casali Karina R, Dias Lucinara D, Irigoyen Maria, Schaan Beatriz D   +8 more
doaj   +1 more source

Pericapsular nerve group block with phenol for non‐operative hip fracture management in patients living with frailty: a prospective multicentre cohort study

Anaesthesia, Volume 81, Issue 12, Page 1673-1685, December 2026.
Summary Introduction The incidence of hip fractures is rising with the ageing population. For patients living with severe frailty and limited life expectancy, non‐operative management is increasingly considered after shared decision‐making. Given the limited availability of long‐term analgesic options, alternative techniques are needed.
Rachel J. H. Smits, Marte I. Lommerse, Hugo H. Wijnen, Lennart G. Wasmoeth, Glenn van de Vossenberg, Gezina T. M. L. Oei, Henk J. Schuijt, Kris C. P. Vissers, Hanna C. Willems, Jan Willem Kallewaard, Selina E. I. van der Wal, the Dutch‐PENG registry collaborators, Gert R. Roukema, Dawi Van der Stap, J.S.H.A. (Seppe) Koopman, Bart P.A. Spaetgens, Renée Brüggemann, Nicole Lefel, Manon Vugts, Nikki M.F. Noorda, Vincent Van Dongen, Hidde Krot, Nicole Grupa, Daisy Hoofwijk, Léon Timmerman   +24 more
wiley   +1 more source

Therapeutic effects of renal denervation on renal failure

, 2013
Sympathetic nerve activity (SNA) is increased in both patients and experimental animals with renal failure. The kidney is a richly innervated organ and has both efferent and afferent nerves.
Wang, Yutang, Golledge, Jonathan, Seto, Saiwang (R18101), Seto, Sai-Wang   +3 more
core   +1 more source

Renal Sympathetic Denervation for the Treatment of Difficult-to-Control or Resistant Hypertension

International Journal of Hypertension, 2011
Hypertension represents a major health problem with an appalling annual toll. Despite the plethora of antihypertensive drugs, hypertension remains resistant in a considerable number of patients, thus creating the need for alternative strategies ...
Vasilios Papademetriou, Michalis Doumas, Konstantinos Tsioufis   +2 more
doaj   +1 more source