Cardamonin upregulate sd the intestinal metabolite columbianetin acetate, which competitively bound HMGB1 to prevent LPS‐induced renal tubular cell pyroptosis (the figure is created with BioRender). ABSTRACT Sepsis‐associated acute kidney injury (SA‐AKI) results in high mortality due to the lack of effective interventions. The current study reports the
Zihui Zhou +6 more
wiley +1 more source
Correlates of symptom burden in renal dialysis patients: a systematic review and meta-analysis. [PDF]
Lu Y +6 more
europepmc +1 more source
Schematic illustration of pH‐responsive SC@AP@INS for oral insulin delivery. (A) pH‐responsive mechanism of sodium alginate‐based hydrogels. (B) Preparation of drug‐loaded microsphere gel via the electrospray method. The controlled release of drug‐loaded micelles in the colon enhances insulin delivery efficiency while minimizing systemic exposure and ...
Minghui Kong +3 more
wiley +1 more source
Elranatamab treatment in a multiple myeloma patient undergoing renal dialysis. [PDF]
Van de Wyngaert Z +7 more
europepmc +1 more source
Cardiovascular risk and mortality in end-stage renal disease patients undergoing dialysis: sleep study, pulmonary function, respiratory mechanics, upper airway collapsibility, autonomic nervous activity, depression, anxiety, stress and quality of life: a prospective, double blind, randomized controlled clinical trial [PDF]
Israel dos Reis dos Santos +23 more
openalex +1 more source
Harnessing Free Radical Scavenging Potential of Caffeic Acid as a Nutraceutical—A Review
Caffeic acid has emerged as a promising bioactive molecule with multiple pharmacological properties, including antioxidant, antimicrobial, anti‐inflammatory, organ protective properties and metal‐chelating ability. This review emphasizes the dietary sources, structural characteristic, molecular mechanism underlying health promoting effects of caffeic ...
Pavitra Behra +2 more
wiley +1 more source
Renal function in patients with non-dialysis chronic kidney disease receiving intravenous ferric carboxymaltose: an analysis of the randomized FIND-CKD trial [PDF]
Iain C. Macdougall +9 more
openalex +1 more source
Construction of Chronic Kidney Disease Mouse Model Induced by Diets With Different Adenine Content
By administering a 4 weeks adenine diet to C57BL/6J mice, we identified 0.2% adenine in purified feed as the optimal chronic kidney disease model. This model induces severe renal damage, gut dysbiosis, uremic toxin accumulation, and CKD mineral bone disorder, providing a clinically relevant platform for mechanistic and therapeutic studies.
Wanjun Liao +8 more
wiley +1 more source

