Results 21 to 30 of about 707,089 (268)

KYA1797K, a Novel Small Molecule Destabilizing β-Catenin, Is Superior to ICG-001 in Protecting against Kidney Aging

Kidney Diseases, 2022
Introduction: Aged kidney is characterized by mitochondrial dysfunction, cellular senescence, and fibrogenesis. The activation of Wnt/β-catenin signaling plays an important role in the initiation of kidney aging.
Mingsheng Zhu, Xian Ling, Shan Zhou, Ping Meng, Qiyan Chen, Shuangqin Chen, Kunyu Shen, Chao Xie, Yaozhong Kong, Maosheng Wang, Lili Zhou   +10 more
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The Efficacy of Triptolide in Preventing Diabetic Kidney Diseases: A Systematic Review and Meta-Analysis

Frontiers in Pharmacology, 2021
Ethnopharmacological Relevance: Triptolide (TP), the primary biologically active ingredient of Tripterygium wilfordii Hook F (TWHF), possesses the potential to solve the shortcomings of TWHF in treating diabetic kidney disease (DKD) in the clinic.Aim of ...
Dongning Liang, Dongning Liang, Hanwen Mai, Hanwen Mai, Fangyi Ruan, Fangyi Ruan, Haiyan Fu   +6 more
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Renal Insufficiency and Failure

Hematology, 2010
Abstract Renal impairment is a common complication of multiple myeloma. Chronic renal failure is classified according to glomerular filtration rate as estimated by the MDRD (modification of diet in renal disease) formula, while RIFLE (risk, injury, failure, loss and end-stage renal disease) and AKIN (acute renal injury network) criteria ...
Dimopoulos, Meletios A., Terpos, Evangelos   +1 more
openaire   +5 more sources

Prevention of cisplatin nephrotoxicity [PDF]

Journal of Nephropharmacology, 2016
Cisplatin has a well-established role in the treatment of broad spectrum of malignancies; however its use is limited because of cisplatin-induced nephrotoxicity (CIN) which can be progressive in more than 50% of cases. The most important risk factors for
Hayati Fatemeh, Hossainzadeh Mehran, Shayanpour Shokouh, Abedi-Gheshlaghi Zahra, Beladi Mousavi Seyed Seifollah   +4 more
doaj  

Inhibition of calpain9 attenuates peritoneal dialysis-related peritoneal fibrosis

Frontiers in Pharmacology, 2022
Aim: Peritoneal dialysis is a common renal replacement method for end-stage renal disease. Long-term peritoneal dialysis leads to peritoneal dialysis-related peritoneal fibrosis, which leads to a cessation of treatment.
Fang Li, Yu Wang, Jianwei Tian, Zhanmei Zhou, Wei Yin, Xianhui Qin, Huizhen Wang, Tao Zeng, Aiqing Li, Jianping Jiang   +9 more
doaj   +1 more source

Mobile Phone Use, Genetic Susceptibility and New-Onset Chronic Kidney Diseases

International Journal of Public Health, 2023
Objective: To examine the associations of mobile phone use and its use characteristics with new-onset CKD.Methods: 408,743 participants without prior CKD in the UK Biobank were included.
Yuanyuan Zhang, Yuanyuan Zhang, Yuanyuan Zhang, Yuanyuan Zhang, Yanjun Zhang, Yanjun Zhang, Yanjun Zhang, Yanjun Zhang, Ziliang Ye, Ziliang Ye, Ziliang Ye, Ziliang Ye, Sisi Yang, Sisi Yang, Sisi Yang, Sisi Yang, Mengyi Liu, Mengyi Liu, Mengyi Liu, Mengyi Liu, Qimeng Wu, Qimeng Wu, Qimeng Wu, Qimeng Wu, Chun Zhou, Chun Zhou, Chun Zhou, Chun Zhou, Panpan He, Panpan He, Panpan He, Panpan He, Xianhui Qin, Xianhui Qin, Xianhui Qin, Xianhui Qin   +35 more
doaj   +1 more source

Gabapentin for treatment of restless legs syndrome among hemodialysis patients; a pilot study [PDF]

Journal of Nephropharmacology, 2018
Introduction: Unfortunately the restless leg syndrome (RLS) is a neglected issue among hemodialysis (HD) centers. Objectives: The aim of our study was to find the efficacy of gabapentin at a low dose of 100 mg three times a week among HD patients with ...
Seyed Majid Mousavi Movahed, Gholamreza Alizadeh Attar, Fatemeh Hayati, Shahla Ahmadi Halili, Leila Sabetnia, Seyed Seifollah Beladi Mousavi   +5 more
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The effect of the omega-3 supplement on uremic pruritus in hemodialysis patients; a double-blind randomized controlled clinical trial [PDF]

Journal of Nephropathology, 2019
Background: Chronic kidney disease (CKD) and uremic syndrome cause malfunction in most of organs including skin. Objectives: This study was designed to investigate the effects of omega-3 supplement on uremic pruritus in chronic hemodialysis patients ...
Shokouh Shayanpour, Seyed Seyfollah Beladi Mousavi, Parastoo Lakhaye Rizi, Bahman Cheraghian   +3 more
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CXC Chemokine Receptor 2 Accelerates Tubular Cell Senescence and Renal Fibrosis via β-Catenin-Induced Mitochondrial Dysfunction

Frontiers in Cell and Developmental Biology, 2022
Renal fibrosis is a common feature of various chronic kidney diseases (CKD). However, its underlying mechanism has not been totally clarified. C-X-C motif chemokine receptor (CXCR) family plays a role in renal fibrosis, however, detailed mechanisms have ...
Ping Meng, Ping Meng, Jiewu Huang, Xian Ling, Shan Zhou, Jingyan Wei, Mingsheng Zhu, Jinhua Miao, Weiwei Shen, Jiemei Li, Huiyun Ye, Hongxin Niu, Yunfang Zhang, Lili Zhou   +13 more
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Baseline Serum Bilirubin and Risk of First Stroke in Hypertensive Patients

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Data on the association between serum bilirubin and the risk of stroke are limited and inconclusive. We aimed to evaluate the association between serum bilirubin and the risk of first stroke and to examine any possible effect modifiers in ...
Jiancheng Wang, Xianglin Zhang, Zhuxian Zhang, Yuanyuan Zhang, Jingping Zhang, Huan Li, Youbao Li, Binyan Wang, Jing Nie, Min Liang, Guobao Wang, Yefeng Cai, Jianping Li, Yan Zhang, Yong Huo, Yimin Cui, Xiping Xu, Xianhui Qin   +17 more
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