Results 71 to 80 of about 1,097,600 (313)
Hyperglucagonemia of Renal Failure [PDF]
Journal of Clinical Investigation, 1974 Elevation of plasma glucagon concentration has been observed in starvation and illnesses associated with increased catabolism such as diabetes mellitus and severe infections. Thus, we examined plasma glucose, immunoreactive insulin (IRI, microunits per milliliter) and glucagon (IRG, picograms per milliliter) responses to a beef meal (1 g/kg body wt ...
Gordon L. Bilbrey +4 more
openaire +2 more sources
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
In-center hemodialysis and COVID 19 infection [PDF]
Journal of Preventive Epidemiology, 2020 Seyed Seifollah Beladi Mousavi +2 more
doaj +1 more source
BMC MedicineBackground The liver effects of concentrated vs. more evenly distributed moderate-to-vigorous physical activity (MVPA) patterns remain unclear. We aimed to examine the association of accelerometer-measured MVPA and different MVPA patterns with liver ...
Mengyi Liu +8 more
doaj +1 more source
Serum alkaline phosphatase levels and the risk of new-onset diabetes in hypertensive adults
Cardiovascular Diabetology, 2020 Background The association between alkaline phosphatase (ALP) and incident diabetes remains uncertain. Our study aimed to investigate the prospective relation of serum ALP with the risk of new-onset diabetes, and explore possible effect modifiers, in ...
Yuanyuan Zhang +12 more
doaj +1 more source
Rationale and study design of intravenous loop diuretic administration in acute heart failure. DIUR-AHF [PDF]
, 2017 Aims: Although loop diuretics are the most commonly used drugs in acute heart failure (AHF) treatment, their short-term and long-term effects are relatively unknown.
Di Somma, Salvatore +5 more
core +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Perbedaanindeks Massa Tubuh (IMT) Pada Pasien Gagal Ginjal Kronik Dengan DM Dan Tanpa DM Yang Menjalani Hemodialisis Rutin Di RSUD Dr. Moewardi [PDF]
, 2018 Chronic kidney disease (CKD) is a disease that leads to progressive kidney function decline, and usually ends with renal failure. The prevalence of CKD in Indonesia is 0.2% and increases with age. DM ranks second as the cause of CKD. Hemodialysis becomes
-, dr. Suryo Aribowo T., M.Kes., Sp.PD (KHOM) +1 more
core
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source