Results 231 to 240 of about 1,236,008 (363)

Verteporfin‐Mediated In Situ Nanovaccine Based on Local Conventional‐Dose Hypofractionated Radiotherapy Enhances Antitumor and Immunomodulatory Effect

Advanced Science, EarlyView.
Here gelatinase‐responsive methoxypolyethyleneglycol–PVGLIG–polycaprolactone (mPEG–PVGLIG–PCL) nanoparticles’ loading verteporfin (N@VP) is developed, enhancing radiotherapy via X‐ray‐triggered singlet oxygen generation. Combined with 2 Gy (gray, a radiation dose unit) irradiation, N@VP achieves antitumor efficacy comparable to 8 Gy, and also promotes ...
Zhifan Zhang, Lin Li, Yuchen Ge, Anni Chen, Shanchao Diao, Yueling Yang, Qianyue Chen, Yingling Zhou, Jie Shao, Fanyan Meng, Lixia Yu, Manman Tian, Xiaoping Qian, Zhaoyu Lin, Chen Xie, Baorui Liu, Rutian Li   +16 more
wiley   +1 more source

Renal Function and the Role of the Renin-Angiotensin-Aldosterone System (RAAS) in Normal Pregnancy and Pre-Eclampsia. [PDF]

J Clin Med
Tsikouras P, Nikolettos K, Kotanidou S, Kritsotaki N, Oikonomou E, Bothou A, Andreou S, Nalmpanti T, Chalkia K, Spanakis V, Tsikouras N, Pagkaki C, Iatrakis G, Damaskos C, Garmpis N, Machairiotis N, Nikolettos N.   +16 more
europepmc   +1 more source

Book Review: Reflections on Renal Function [PDF]

, 1955

openalex   +1 more source

Machine Learning‐Enabled Drug‐Induced Toxicity Prediction

Advanced Science, EarlyView.
Unexpected toxicity accounts for 30% of drug development failures. This review highlights ML innovations in predicting drug‐induced toxicity, emphasizing comparative analyses, interpretable algorithms, and multi‐source data integration. It categorizes toxicity types, summarizes ML models, and organizes key databases, offering strategies to address ...
Changsen Bai, Lianlian Wu, Ruijiang Li, Yang Cao, Song He, Xiaochen Bo   +5 more
wiley   +1 more source

The impact of low-protein diet on residual renal function in dialysis patients: a systematic review and metaanalysis. [PDF]

BMC Nephrol
Xie J, Liu X, Ling Y, Ge S, Yao Y.
europepmc   +1 more source

Single‐Cell Atlas Reveals Tumorigenic Profiles and Immune Dynamics of Adrenal Incidentalomas

Advanced Science, EarlyView.
Single‐cell RNA sequencing reveals cellular heterogeneity in adrenal incidentalomas, identifying distinct tumor cell populations. Clusterin is recognized as a biomarker for adrenocortical tumors, correlating with established markers. MYCN‐positive clusters in pheochromocytomas indicated poorer survival.
Meng Wang, Guangmin Zheng, Xiaoyong Hu, Feng Tian, Tuo Li, Zheng Zhang, Kan Gong, Shiwei Chen, Lin Yuan, Yu Qi, Lin Li, Daofu Cheng, Liu Liu, Fuqiang Liu, Yujing Sun, Xiangdong Fang, Ruxing Zhao, Bing Liu, Chao Zhang   +18 more
wiley   +1 more source

Investigation of renal function in patients with long COVID in the Amazon region: a cross-sectional study. [PDF]

BMC Infect Dis
Assis GMCC, Veiga IGD, Reis RNR, Menezes DC, Xavier SS, Chaves ECR, Sousa JR, Quaresma JAS, Falcão LFM, Lima PDL.   +9 more
europepmc   +1 more source

4D Biofabrication of Magnetically Augmented Callus Assembloid Implants Enables Rapid Endochondral Ossification via Activation of Mechanosensitive Pathways

Advanced Science, EarlyView.
Magnetically augmented biohybrid cartilaginous microtissues enable remote microtissue motion control and assembly as well as targeted differentiation. This study demonstrates accelerated endochondral ossification under magnetic stimulation, highlighting cartilaginous assembloid constructs’ ability to retain long‐term magnetic properties.
Konstantinos Ioannidis, Andreas Dimopoulos, Isaak Decoene, Maya Guilliams, Hanna Svitina, Liudmyla Storozhuk, Rodrigo de Oliveira‐Silva, Sergey Basov, Nguyen Thi Kim Thanh, Stefanos Mourdikoudis, Margriet J. Van Bael, Bart Smeets, Dimitrios Sakellariou, Ioannis Papantoniou   +13 more
wiley   +1 more source

Assessment of the renal function of patients with anorexia nervosa. [PDF]

Biopsychosoc Med
Miyahara H, Shigeyasu Y, Fujii C, Tanaka C, Hanzawa M, Sugihara A, Okada A, Tsukahara H.   +7 more
europepmc   +1 more source

Efficient and Specific PDGFRβ‐Targeting Dual‐Mode T1‐T2 MRI Nanoprobe for Early Diagnosis of Non‐Alcoholic Fatty Liver

Advanced Science, EarlyView.
The Fe3O4/Gd@BSA‐pPB nanoprobe leverages biomimetic mineralization and targets hepatic stellate cells (HSCs) through PDGFRβ, offering superior enrichment in fibrotic regions. This targeted delivery overcomes biological barriers, enhancing both the accuracy and sensitivity of MRI imaging at early disease stages.
Zehua Li, Tongwei Zhang, Tongxiang Tao, Yaxuan Liu, Haining Xia, Sajid ur Rehman, Zeyong Guo, Jing Zhang, Ruiguo Chen, Zhan Zhang, Junfeng Wang, Kun Ma   +11 more
wiley   +1 more source