Results 261 to 270 of about 1,236,008 (363)

Altered Neural Activity in the Mesoaccumbens Pathway Underlies Impaired Social Reward Processing in Shank3‐Deficient Rats

open access: yesAdvanced Science, EarlyView.
This study examines the effects of Shank3 mutation on the mesoaccumbens pathway using a Shank3‐deficient rat model. The findings reveal altered social reward processing in these rats, accompanied by changes in dopaminergic and GABAergic neural activity within the ventral tegmental area (VTA) and dopamine release in the nucleus accumbense (NAc ...
Marie Barbier   +4 more
wiley   +1 more source

Correction: Assessment of the renal function of patients with anorexia nervosa. [PDF]

open access: yesBiopsychosoc Med
Miyahara H   +7 more
europepmc   +1 more source

Metabolomic and Cellular Mechanisms of Drug‐Induced Ototoxicity and Nephrotoxicity: Therapeutic Implications of Uric Acid Modulation

open access: yesAdvanced Science, EarlyView.
Drug‐induced renal damage impairs uric acid excretion, causing its accumulation in the serum, which subsequently infiltrates the cochlea. Xanthine oxidase and the ABCG2 transporter, critical in uric acid metabolism and excretion, undergo pathological changes in renal tubular and cochlear stria vascularis cells.
Suhan Guo   +11 more
wiley   +1 more source

Mitigating Doxorubicin‐Induced Cardiotoxicity and Enhancing Anti‐Tumor Efficacy with a Metformin‐Integrated Self‐Assembled Nanomedicine

open access: yesAdvanced Science, EarlyView.
A novel self‐assembled nanomedicine (PMDDH) has been developed for the co‐delivery of doxorubicin and metformin, aiming to enhance the anti‐tumor efficacy of doxorubicin while alleviating its cardiotoxicity through the activation of cGAS‐STING and AMPK signaling pathways, respectively.
Jiaxin Huang   +9 more
wiley   +1 more source

Is body composition important in the context of renal function in pediatric neurogenic bladder? [PDF]

open access: yesPediatr Nephrol
Bagińska-Chyży J   +2 more
europepmc   +1 more source

RAB3B Dictates mTORC1/S6 Signaling in Chordoma and Predicts Response to mTORC1‐Targeted Therapy

open access: yesAdvanced Science, EarlyView.
RAB3B is unveiled as a prominent oncogenic regulator in chordoma, which can block the DUSP12‐mediated dephosphorylation of p‐S6 (S235/236). The combination of RAB3B and p‐S6 indicates a good prognostic value and predicts mTORC1 inhibitors response for chordoma patients.
Jianxuan Gao   +15 more
wiley   +1 more source

Renal function outcomes in living kidney donors in a transplant center in Colombia. [PDF]

open access: yesSAGE Open Med
Torres R   +9 more
europepmc   +1 more source

Renal function after exstrophy repair

open access: yesEuropean Urology Open Science, 2020
C. Sinatti   +4 more
doaj  

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