"Suboptimal" kidney donors: The experience with tacrolimus-based immunosuppression [PDF]
Female, pediatric, and older donors have been associated with inferior graft survival after renal transplantation. We analyzed these three subgroups in 397 patients receiving tacrolimus-based immunosuppression. There were no differences in recipient age,
Alexander +23 more
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Pathfinder cells provide a novel therapeutic intervention for acute kidney injury [PDF]
Pathfinder cells (PCs) are a novel class of adult-derived cells that facilitate functional repair of host tissue. We used rat PCs to demonstrate that they enable the functional mitigation of ischemia reperfusion (I/R) injury in a mouse model of renal ...
Alan MacIntyre +11 more
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Anti-CTLA-4 (CD 152) monoclonal antibody-induced autoimmune interstitial nephritis [PDF]
Targeted immune-modulating agents are entering clinical practice in many specialties, providing novel therapeutic possibilities but introducing new potential toxicities.
Clatworthy, Menna R +4 more
core +2 more sources
Current Perspective on the Location and Function of Gamma- Aminobutyric Acid (GABA) and its Metabolic Partners in the Kidney. [PDF]
Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter located in the mammalian central nervous system, which binds to GABAA and GABAB receptors to mediate its neurological effects.
Dunn, Kadeshia +3 more
core +1 more source
Splenectomy and Thymectomy in Human Renal Homotransplantation [PDF]
Five patients with terminal renal failure have been treated with renal homografts. Total body irradiation and cytotoxic drugs were used to prevent rejection.
Marchioro, TL +3 more
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Obstetric and long-term kidney outcomes in renal transplant recipients: a 40 year single-centre study [PDF]
Female renal transplant recipients of childbearing age may ask what the outcomes are for pregnancy and whether pregnancy will affect graft function. We analyzed obstetric and transplant outcomes among renal transplant recipients in our center who have ...
Brennand, Janet E. +6 more
core +1 more source
Cardiovascular disease biomarkers are associated with declining renal function in type 2 diabetes [PDF]
Aims/hypothesis: We investigated whether biochemical cardiovascular risk factors and/or markers of subclinical cardiovascular disease were associated with the development of reduced renal function in people with type 2 diabetes.
Conway, Bryan R. +9 more
core +3 more sources
Evaluation of renal function by dynamic MR imaging: effect of water load. [PDF]
The aim of this study was to investigate the usefulness of magnetic resonance (MR) imaging in the evaluation of renal function, with particular attention to the effects of water load. Ten healthy volunteers underwent dynamic MR imaging after an injection
Hiraki, Yoshio +2 more
core +1 more source
A brief review of the literature on the malignant ureteral obstruction [PDF]
Malignant ureteral obstruction (MUO) caused by a primarily urological tumor or secondary to a late-stage malignancy can be difficult for the urologist to manage. Due to a lack of clinical data on the management of MUO, every case is particular and should
Brînză, Adrian +7 more
core +1 more source
Association between urinary sodium, creatinine, albumin, and long term survival in chronic kidney disease [PDF]
Dietary sodium intake is associated with hypertension and cardiovascular risk in the general population. In patients with chronic kidney disease, sodium intake has been associated with progressive renal disease, but not independently of proteinuria.
Fox, Jonathan G. +6 more
core +1 more source

