Impact of Renal Impairment on Beta-Blocker Efficacy in Patients With Heart Failure. [PDF]
BACKGROUND: Moderate and moderately severe renal impairment are common in patients with heart failure and reduced ejection fraction, but whether beta-blockers are effective is unclear, leading to underuse of life-saving therapy.
Andersson, B+22 more
core +8 more sources
Reversal of hepatorenal syndrome type 1 with terlipressin plus albumin vs. placebo plus albumin in a pooled analysis of the OT-0401 and REVERSE randomised clinical studies [PDF]
Background The goal of hepatorenal syndrome type 1 (HRS-1) treatment is to improve renal function. Terlipressin, a synthetic vasopressin analogue, is a systemic vasoconstrictor used for the treatment of HRS-1, where it is available.
Araya, V.+11 more
core +2 more sources
Evaluation of Renal Function in Children with Wilson’s Disease
Introduction: In this study it was aimed to evaluate the renal functions in Wilson’s disease (WD) using urinary N-acetyl-β-D-glucosaminidase (NAG) and NAG/creatinine activity index.
Yılmaz Tabel+5 more
doaj +1 more source
SGLT2 Inhibitors and the Diabetic Kidney [PDF]
Diabetic nephropathy (DN) is the most common cause of end-stage renal disease worldwide. Blood glucose and blood pressure control reduce the risk of developing this complication; however, once DN is established, it is only possible to slow progression ...
Busetto, Luca+4 more
core +1 more source
Hu Ai,1,* Hui-Ping Zhang,1,* Guo-Jian Yang,1 Nai-Xin Zheng,1 Guo-Dong Tang,1 Hui Li,1 Qi Zhou,2 Jun-Hong Ren,3 Ying Zhao,1 Fu-Cheng Sun1 1Department of Cardiology, Beijing Hospital, National Center of Gerontology, Beijing, 100730, China; 2The MOH Key ...
Ai H+9 more
doaj
The effect of warm ischemia time (WIT) on longterm renal function after partial nephrectomy remains controversial. In this retrospectively cohort study, 75 solitary kidney patients were included and the effects of warm ischemia time, preoperative renal ...
Zhu Jie+11 more
doaj +1 more source
Pathfinder cells provide a novel therapeutic intervention for acute kidney injury [PDF]
Pathfinder cells (PCs) are a novel class of adult-derived cells that facilitate functional repair of host tissue. We used rat PCs to demonstrate that they enable the functional mitigation of ischemia reperfusion (I/R) injury in a mouse model of renal ...
Alan MacIntyre+11 more
core +1 more source
Reduced CD40L expression on ex vivo activated CD4+T-lymphocytes from patients with excellent renal allograft function measured with a rapid whole blood flow cytometry procedure [PDF]
Background: The CD40-CD40L (CD154) costimulatory pathway plays a critical role in the pathogenesis of kidney allograft rejection. In renal transplant biopsies, CD4+ CD40L+ graft-infiltrating cells were detected during chronic rejection in contrast to ...
Friedrich, N.+5 more
core +1 more source
Association between pulmonary function and renal function: findings from China and Australia
Background The relationship between obstructive lung function and impaired renal function is unclear. This study investigated the dose-response relationship between obstructive lung function and impaired renal function.
Dahai Yu+4 more
doaj +1 more source
Relationship of Renal Echogenicity with Renal Pathology and Function [PDF]
Purpose Renal ultrasonography has been widely used in children with renal disease. However, the relationship of renal echogenicity with renal pathology and function in children is not well known.
Jin Hee Lee+4 more
doaj +1 more source