Results 41 to 50 of about 1,352,945 (362)

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

ULTRASONOGRAPHIC MEASUREMENT OF RENAL CORTICAL THICKNESS AND RENAL LENGTH INADULTS WITH NORMAL RENALFUNCTION [PDF]

Perspectives In Medical Research, 2019
Background/Objective: Renal cortical thickness and renal length are important indices for many renal diseases. Ultrasonography has been introduced as an effective method to determine different renal measurements.
Priyanka Racha1, Sushmitha2 ,VikasChennamaneni3
doaj  

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Urinary active transforming growth factor ß in feline chronic kidney disease [PDF]

, 2016
The cytokine transforming growth factor beta 1 (TGF-β1) has been widely implicated in the development and progression of renal fibrosis in chronic kidney disease (CKD) in humans and in experimental models.
Annes, Arata, Armbruster, Border, Brown, Brown, C.P.D. Wheeler-Jones, Chakrabarti, Chakrabarti, De Muro, DiBartola, Dukanovic, Edwards, Elliott, Ellis, H.M. Syme, Habenicht, He, Honkanen, J. Elliott, J.S. Lawson, Keegan, Khan, Krag, Liu, Lulich, Marino, Murakami, Rogier, Rohatgi, Ruiz-Torres, Serini, Shaker, Sharma, Shin, Swan, Syme, Wakefield, Watanabe, Wolf, Wu   +40 more
core   +1 more source

The error of estimated GFR in predialysis care

Scientific Reports
The error of estimated glomerular filtration rate (eGFR) and its consequences in predialysis are unknown. In this prospective multicentre study, 315 predialysis patients underwent measured GFR (mGFR) by the clearance of iohexol and eGFR by 52 formulas ...
Beatriz Escamilla-Cabrera, Sergio Luis-Lima, Eduardo Gallego-Valcarce, Nuria Victoria Sánchez-Dorta, Natalia Negrín-Mena, Laura Díaz-Martín, Coriolano Cruz-Perera, Ana Monserrat Hernández-Valles, Federico González-Rinne, María José Rodríguez-Gamboa, Sara Estupiñán-Torres, Rosa Miquel-Rodríguez, María Ángeles Cobo-Caso, Patricia Delgado-Mallén, Gema Fernández-Suárez, Ana González-Rinne, Grimanesa Hernández-Barroso, Alejandra González-Delgado, Armando Torres-Ramírez, Alejandro Jiménez-Sosa, Alberto Ortiz, Flavio Gaspari, Domingo Hernández-Marrero, Esteban Luis Porrini   +23 more
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Continued monitoring of acute kidney injury survivors might not be necessary in those regaining an estimated glomerular filtration rate > 60 mL/min at 1 year [PDF]

, 2017
Background. Severe acute kidney injury (AKI) among hospitalized patients often necessitates initiation of short-term dialysis. Little is known about the long-term outcome of those who recover to normal renal function.
Geddes, Colin C., Mark, Patrick B., McQuarrie, Emily P., Stoumpos, Sokratis, Traynor, Jamie P.   +4 more
core   +1 more source

The effect of renal function change on renal cell carcinoma patients with tumor thrombus after nephrectomy and thrombectomy: a large Chinese center experience

BMC Cancer, 2020
Background To explore the influencing factors of perioperative renal function change and their relationship with prognosis on renal cell carcinoma (RCC) patients with tumor thrombus after nephrectomy and thrombectomy.
Zhuo Liu, Shiying Tang, Xiaojun Tian, Hongxian Zhang, Guoliang Wang, Shudong Zhang, Lulin Ma   +6 more
doaj   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Treatment of atherosclerotic renovascular hypertension: review of observational studies and a meta-analysis of randomized clinical trials. [PDF]

, 2015
open9Atherosclerotic renal artery stenosis can cause ischaemic nephropathy and arterial hypertension. We herein review the observational and randomized clinical trials (RCTs) comparing medical and endovascular treatment for control of hypertension and ...
Caielli, P, Calò, Frigo, Anna Chiara, Maiolino, G, Miotto, Diego, Pengo, Mf, Rossi, Gianpaolo, Rossitto, G, Seccia, Teresa Maria   +8 more
core   +1 more source