Results 61 to 70 of about 987,918 (314)

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

Trends and predictors of changes in renal function after radical nephrectomy for renal tumours

BMC Nephrology
Background Chronic kidney disease (CKD) is a common postoperative complication in patients who undergo radical nephrectomy for renal tumours. However, the factors influencing long-term renal function require further investigation.
Yongchao Yan, Yunbo Liu, Bin Li, Shang Xu, Haotian Du, Xinning Wang, Yanjiang Li   +6 more
doaj   +1 more source

Predictive abilities of cardiovascular biomarkers to rapid decline of renal function in Chinese community-dwelling population: a 5-year prospective analysis

BMC Nephrology, 2017
Background Predictive abilities of cardiovascular biomarkers to renal function decline are more significant in Chinese community-dwelling population without glomerular filtration rate (GFR) below 60 ml/min/1.73m2, and long-term prospective study is an ...
Shihui Fu, Chunling Liu, Leiming Luo, Ping Ye   +3 more
doaj   +1 more source

Renal Function in the Elderly [PDF]

Nephron, 2008
Etude chez des vieillards des fonctions renales. Comparaison du volume urinaire, de l'excretion urinaire et de la clairance de la creatinine, ainsi que de la creatinine plasmatique (CP) avec les valeurs obtenues avec de jeunes insuffisants renaux. Etude des correlations entre les clairances de la creatine mesurees, calculees, la CP et la vitesse de ...
A, Hadj-Aïssa, C, Dumarest, P, Maire, N, Pozet   +3 more
openaire   +2 more sources

Renal pericytes: regulators of medullary blood flow [PDF]

, 2012
Regulation of medullary blood flow (MBF) is essential in maintaining normal kidney function. Blood flow to the medulla is supplied by the descending vasa recta (DVR), which arise from the efferent arterioles of juxtamedullary glomeruli.
Peppiatt-Wildman, Claire M., Kennedy-Lydon, T M, Wildman, S S P, Peppiatt-Wildman, C M, Peppiatt‐Wildman, C. M., Kennedy‐Lydon, T. M., Wildman, Scott S.P., Kennedy-Lydon, T. M., Crawford, C., Crawford, C, Wildman, S. S. P.   +10 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Sirolimus enhances cyclosporine a-induced cytotoxicity in human renal glomerular mesangial cells [PDF]

, 2012
End Stage Renal Disease (ESRD) is an ever increasing problem worldwide. However the mechanisms underlying disease progression are not fully elucidated. This work addressed the nephrotoxicity induced by the immunosuppressive agents’ cyclosporine A (CsA ...
Ryan, Michael P., Michael P. Ryan, O'Connell, Séin, Slattery, Craig, Tara McMorrow, Craig Slattery, Séin O'Connell, McMorrow, Tara   +7 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

VALUE ASSESSMENT OF RENAL FUNCTION IN RENAL CELL CARCINOMA

Вестник урологии, 2013
Renal cell carcinoma (RCC) accounts for 90-95% of all neoplastic lesions of the kidney. In Russia in 2008 defined 17 563 new cases of RCC. In this common tumor found in 45.6 % of cases. A metastatic forms are still a significant part of RCC – 28-32%.
S. V. Evseev, A. A. Gusev
doaj   +1 more source