Results 71 to 80 of about 987,918 (314)

Renal perfusion in scleroderma patients assessed by microbubble-based contrast-enhanced ultrasound [PDF]

, 2012
OBJECTIVES: Renal damage is common in scleroderma. It can occur acutely or chronically. Renal reserve might already be impaired before it can be detected by laboratory findings.
Himsel, Andrea, Kleinert, Stefan, Roll, Petra, Baumgärtner, Christian, Burkhardt, Harald, Tony, Hans-Peter, Janett, Manfred, Müller, Adelheid, Baumgaertner, Christian, Jenett, Manfred, Fleck, Martin, Feuchtenberger, Martin, Mueller, Adelheid   +12 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Renal Function and Efficacy of Remote Ischemic Conditioning in Acute Moderate Ischemic Stroke: A Post Hoc Analysis of RICAMIS Trial

Brain and Behavior
Background Emerging evidence supports the therapeutic potential of remote ischemic conditioning (RIC) in acute stroke management. This post hoc analysis aims to elucidate the relationship between renal function and the efficacy of RIC.
Xiao‐Yi He, Yu Cui, Jia‐Qi Wang, Lu Wang, Hui‐Sheng Chen   +4 more
doaj   +1 more source

The effect of renal function change on renal cell carcinoma patients with tumor thrombus after nephrectomy and thrombectomy: a large Chinese center experience

BMC Cancer, 2020
Background To explore the influencing factors of perioperative renal function change and their relationship with prognosis on renal cell carcinoma (RCC) patients with tumor thrombus after nephrectomy and thrombectomy.
Zhuo Liu, Shiying Tang, Xiaojun Tian, Hongxian Zhang, Guoliang Wang, Shudong Zhang, Lulin Ma   +6 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Renal function and efficacy of dual antiplatelet vs. alteplase in minor stroke: a post hoc analysis of ARAMIS study

Frontiers in Neurology
BackgroundThis secondary analysis of the ARAMIS trial evaluated renal function’s modifying effects on therapeutic responses to dual antiplatelet therapy (DAPT) versus intravenous thrombolysis in acute minor ischemic stroke.MethodsBased on the as-treated ...
Xiao-Yi He, Xiao-Yi He, Xiao-Yi He, Chao He, Hui-Sheng Chen, Hui-Sheng Chen   +5 more
doaj   +1 more source

Does endoscopic sclerotherapy in filarial chyluria affect renal function and morphology? A prospective study using dimercaptosuccinic acid renal scan

Asian Journal of Urology, 2019
Objective: To look for change in relative renal function and document renal scarring following endoscopic renal pelvic instillation sclerotherapy (RPIS) in patients with chyluria by dimercaptosuccinic acid (DMSA) renal scan.
Bimalesh Purkait, Apul Goel, Satyawati Deswal, Monica Agrawal, BhupendraPal Singh, Manoj Kumar   +5 more
doaj   +1 more source

Renal function diuretics

, 2010
This topic describes the various drugs that affect renal function and introduces diuretics. Diuretics are explored in more detail, specifically the mechanism of action and the different types, including examples.
Raja Habib, St George's, University of London   +1 more
core  

The Course of Renal Function After Radical Cystectomy with Ileal Conduit Diversion for Bladder Cancer [PDF]

, 2019
Objective:We evaluated the course of the renal function and potential risk factors for renal deterioration in patients who had undergone radical cystectomy with ileal conduit diversion.Materials and Methods:A retrospective study evaluated 121 patients ...
Sezgin Güvel, Cevahir Özer, Mehmet Reşit Gören, Tulga Eğilmez, Ferhat Kılınç   +4 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source