Results 71 to 80 of about 6,541,316 (304)

VALUE ASSESSMENT OF RENAL FUNCTION IN RENAL CELL CARCINOMA

Вестник урологии, 2013
Renal cell carcinoma (RCC) accounts for 90-95% of all neoplastic lesions of the kidney. In Russia in 2008 defined 17 563 new cases of RCC. In this common tumor found in 45.6 % of cases. A metastatic forms are still a significant part of RCC – 28-32%.
S. V. Evseev, A. A. Gusev
doaj   +1 more source

The carotid body as a putative therapeutic target for the treatment of neurogenic hypertension [PDF]

, 2013
In the spontaneously hypertensive (SH) rat, hyperoxic inactivation of the carotid body (CB) produces a rapid and pronounced fall in both arterial pressure and renal sympathetic nerve activity (RSA).
Hendy, Emma B, Sobotka, Paul A, Pijacka, Wioletta, Moraes, Davi J A, Abdala, Ana P, Marvar, Paul, McBryde, Fiona D, Paton, Julian F R   +7 more
core   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Lithium treatment reduces the renal kallikrein excretion rate [PDF]

, 1990
Lithium treatment reduces the renal kallikrein excretion rate. Lithium salts are widely used agents for the prophylactic treatment of affective disorders. Lithium salts may be associated with distal nephron dysfunction.
Marin-Grez, Marcos, Sauer, Heinrich, Gross, Peter, Reinhard, Caroline, Fink, Edwin   +4 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Renal function diuretics

, 2010
This topic describes the various drugs that affect renal function and introduces diuretics. Diuretics are explored in more detail, specifically the mechanism of action and the different types, including examples.
Raja Habib, St George's, University of London   +1 more
core  

Systematic analysis of a novel human renal glomerulus-enriched gene expression dataset [PDF]

, 2010
Glomerular diseases account for the majority of cases with chronic renal failure. Several genes have been identified with key relevance for glomerular function.
Clemens D Cohen, Ilka Edenhofer, Felix Eichinger, Rastaldi, Maria P., Maja T. Lindenmeyer, Hans-Joachim Anders, Lindenmeyer, M T, Cohen Clemens D., Eichinger, Felix, Eichinger Felix, Kretzler, Matthias, Mattinzoli, D, Deborah Mattinzoli, Maja T Lindenmeyer, Maria P. Rastaldi, Cohen, Clemens D., Kretzler, M, Sen, Kontheari, Rastaldi Maria P., Matthias Kretzler, Edenhofer, I, Lindenmeyer, Maja T., Anders Hans-Joachim, Clemens D. Cohen, Cohen, C D, Maria P Rastaldi, Mattinzoli Deborah, Mattinzoli, Deborah, Anders, Hans-Joachim, Sen Kontheari, Kretzler Matthias, Edenhofer, Ilka, Kontheari Sen, Lindenmeyer Maja T., Rastaldi, M P, Edenhofer Ilka, Eichinger, F, Sen, K   +37 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Gene expression analysis in microdissected renal tissue - Current challenges and strategies [PDF]

, 2002
The architecture and compartmentalization of the kidney has stimulated the development of an array of microtechniques to study the functional differences between the distinct nephron segments. With the vast amounts of genomic sequence data now available,
Cohen, C. D., Kretzler, M.
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source