Role of renal function in breast cancer
Breast cancer continues to be a major cause of cancer-related death and is the most prevalent disease diagnosed in women worldwide. The need for more trustworthy biomarkers for early diagnosis and prognosis is highlighted by the low sensitivity and ...
Hanan Kamel +3 more
doaj +1 more source
Impact of acute, oral ingestion of hypoxoside from African potato on hepatic and renal function tests in HIV infected patients on combination antiretroviral therapy. [PDF]
Matyanga CMJ +6 more
europepmc +1 more source
Chemical pathology case conference - Renal function tests
Glomerular filtration rate (GFR) is the best index for assessing the overall renal function but it can only be determined indirectly. Measurement of serum creatinine is the simplest and the most widely used method for GFR assessment.
Chan, AKC +9 more
core
Basic renal function tests such as maximum urine osmolality and urinary elimination of albumin and N-acetyl-glucosaminidase often reveal abnormalities in clinical cases involving hyperpressure in the urinary tract or loss of renal parenchyma. However, in
Luis-Yanes, Maria Isabel +7 more
core +1 more source
Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann +17 more
wiley +1 more source
Cognitive Function and White Matter Changes Associated with Renal Transplantation. [PDF]
BackgroundEnd-stage renal disease (ESRD) is a disease with an aging population and a high prevalence of cognitive impairment affecting quality of life, health care costs and mortality. Structural changes in the brain with decreased white matter integrity
Yu, Alan SL +7 more
core +1 more source
Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli +5 more
wiley +1 more source
Assessment of renal function tests in congestive heart failure patients [PDF]
Introducción: Recientemente ha aumentado el interés en estudiar la Enfermedad Renal Crónica (ERC) junto con las enfermedades que frecuentemente se presentan asociadas a ella, como son la ICC y la Anemia, con las que se ...
Perez Canga, José Luis
core
The cost of implementing UK guidelines for the management of chronic kidney disease [PDF]
Background. Chronic kidney disease (CKD) is a major public health problem. In the UK, guidelines have been developed to facilitate case identification and management.
B. Klebe +35 more
core +1 more source
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source

