Results 71 to 80 of about 384,515 (306)

Assessing renal graft function in clinical trials: Can tests predicting glomerular filtration rate substitute for a reference method?

open access: yes, 2004
Assessing renal graft function in clinical trials: Can tests predicting glomerular filtration rate substitute for a reference method?BackgroundIn clinical trials, comparison of renal graft function needs a rigorous determination of glomerular filtration ...
De Filippis, Jean-Pierre   +8 more
core   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Evaluation of Serum Cystatin C levels in Type 2 Diabetes Mellitus Patients with and without Diabetic Nephropathy: A Cross-sectional Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Introduction: Diabetes Mellitus (DM) is a metabolic disorder characterised by insufficient insulin secretion or action that raises blood glucose levels.
Sangeeta Chongtham   +7 more
doaj   +1 more source

Studies on Renal Hypertension Report 3. Study on the Reliability of Differential Renal Function Test in Clinical Cases. [PDF]

open access: yes, 1966
Various types of differential renal function tests have been proposed to diagnose patients with renovascular hypertension. These are all based upon experiments demonstrating that partial clumping of the renal artery results in a markedly increased ...
池田, 務
core   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

The Renal Function Tests in Relation to Immediate Prognosis [PDF]

open access: yes, 1929
The Renal Function Tests by themselves are of great assistance in prognosis, but fail to help in the immediate outlook, as they do not indicate whether the patient may survive for months or years. The Urea Concentration Test gives the greatest assistance,
Adam, John
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Trends and predictors of changes in renal function after radical nephrectomy for renal tumours

open access: yesBMC Nephrology
Background Chronic kidney disease (CKD) is a common postoperative complication in patients who undergo radical nephrectomy for renal tumours. However, the factors influencing long-term renal function require further investigation.
Yongchao Yan   +6 more
doaj   +1 more source

Observation of renal function in patients with surgical jaundice

open access: yes, 2014
SummaryIntroductionThe association between surgical jaundice and postoperative acute renal failure (ARF) has been recognized since long. Obstructive (surgical) jaundice is a common entity, and patients undergoing surgery have a constant risk of ...
Jha, N.K., Rai, Arpita, Kumar, Ansul
core   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy