Results 1 to 10 of about 1,613,591 (292)

A systematic review on the accumulation of prophylactic dosages of low-molecular-weight heparins (LMWHs) in patients with renal insufficiency [PDF]

European Journal of Clinical Pharmacology, 2015
Purpose Although therapeutic dosages of most low-molecular-weight heparins (LMWHs) are known to accumulate in patients with renal insufficiency, for the lower prophylactic dosages this has not been clearly proven.
F. Atiq, P. M. van den Bemt, F. Leebeek, T. van Gelder, J. Versmissen   +4 more
core   +2 more sources

Glucose-induced down regulation of thiamine transporters in the kidney proximal tubular epithelium produces thiamine insufficiency in diabetes [PDF]

, 2012
Increased renal clearance of thiamine (vitamin B1) occurs in experimental and clinical diabetes producing thiamine insufficiency mediated by impaired tubular re-uptake and linked to the development of diabetic nephropathy.
A Adaikalakoteswari, A AntonySunil, A Makino, A Turano, Anindita Das, AO Phillips, B Ashokkumar, B Dutta, B Sihag, BR Chamberlain, CME Tallaksen, Daniel Zehnder, ED Schleicher, Fang Zhang, G Gastaldi, GLJ Page, Guerman Molostvov, H Lum, H Smithline, HM Said, I Hubatsch, J Rieck, James R. Larkin, JC Reidling, JC Reidling, JC Reidling, JD Eudy, KA Robinson, Lisa Godfrey, MJ Boulware, MJ Ryan, MW Pfaffl, N Rabbani, N Rabbani, N Takahashi, N Tasevska, Naila Rabbani, Paul J. Thornalley, PJ Thornalley, R Babaei-Jadidi, S Sander, SM Nabokina, VS Subramanian   +42 more
core   +9 more sources

Comparing the Population Pharmacokinetics of and Acute Kidney Injury Due to Polymyxin B in Chinese Patients with or without Renal Insufficiency

Antimicrobial Agents and Chemotherapy, 2020
Despite excellent bactericidal effect, dosing adjustment of polymyxin B for patients with renal insufficiency and polymyxin B-related nephrotoxicity is still a major concern to clinicians.
Peile Wang, Qiwen Zhang, Zhenfeng Zhu, H. Pei, Min Feng, T. Sun, Jing Yang, Xiaojian Zhang   +7 more
semanticscholar   +1 more source

Binding of bromocresol green and bromocresol purple to albumin in hemodialysis patients [PDF]

, 2017
BACKGROUND: Colorimetric albumin assays based on binding to bromocresol purple (BCP) and bromocresol green (BCG) yield different results in chronic kidney disease. Altered dye binding of carbamylated albumin has been suggested as a cause.
Delanghe, Joris, Delanghe, Sigurd, Eloot, Sunny, Glorieux, Griet, Pletinck, Anneleen, Schepers, Eva, Speeckaert, Marijn, Van Biesen, Wim, Van de Velde, Nadeige   +8 more
core   +1 more source

How to improve drug dosing for patients with renal impairment in primary care - a cluster-randomized controlled trial [PDF]

, 2012
Background: Patients with chronic kidney disease (CKD) are at increased risk for inappropriate or potentially harmful prescribing. The aim of this study was to examine whether a multifaceted intervention including the use of a software programme for the ...
Beyer, Martin, Erler, Antje, Gerlach, Ferdinand M., Haefeli, Walter E., Petersen, Juliana, Rath, Thomas, Rochon, Justine, Saal, Kristina   +7 more
core   +1 more source

Urinary NGAL and RBP Are Biomarkers of Normoalbuminuric Renal Insufficiency in Type 2 Diabetes Mellitus

Journal of Immunological Research, 2019
Objectives As a screening index of diabetic kidney disease (DKD), urinary albumin/creatine ratio (UACR) is commonly used. However, approximately 23.3%-56.6% of DKD patients with estimated glomerular filtration rate (eGFR) < 60 ml/min per 1.73 m2 are ...
Ai-mei Li, B. Yi, Yan Liu, Jianwen Wang, Qing Dai, Yuxi Huang, Y. Li, Hao Zhang   +7 more
semanticscholar   +1 more source

The impact on quality of life of dialysis patients with renal insufficiency

Patient Preference and Adherence, 2018
Aim The aim of the study was the subjective assessment of the quality of life (QoL) of 140 patients treated with dialysis (peritoneal dialysis and hemodialysis). Background Chronic kidney disease and the methods of its treatment play an important part in
M. Dąbrowska-Bender, Grażyna Dykowska, Wioletta Żuk, M. Milewska, A. Staniszewska   +4 more
semanticscholar   +1 more source

Renal insufficiency and cancer treatments

ESMO Open, 2016
Renal insufficiency has been shown to be highly prevalent in patients with cancer. This renal insufficiency has been reported to be associated with reduced overall survival and increased cancer-related mortality.
V. Launay-Vacher, N. Janus, G. Deray
semanticscholar   +1 more source

Diabetic kidney disease. new clinical and therapeutic issues. Joint position statement of the Italian Diabetes Society and the Italian Society of Nephrology on "the natural history of diabetic kidney disease and treatment of hyperglycemia in patients with type 2 diabetes and impaired renal function" [PDF]

, 2019
Recent epidemiological studies have disclosed heterogeneity in diabetic kidney disease (DKD). In addition to the classical albuminuric phenotype, two new phenotypes have emerged, i.e., “nonalbuminuric renal impairment” and “progressive renal decline ...
Barutta, Federica, De Nicola, Luca, Di Paolo, Salvatore, Gesualdo, Loreto, Natali, Andrea, Penno, Giuseppe, Pugliese, Giuseppe, Reboldi, Gianpaolo   +7 more
core   +1 more source

The hepatoadrenal syndrome: A common yet unrecognized clinical condition [PDF]

, 2005
Objective: Adrenal failure is common in critically ill patients, particularly those with sepsis. As liver failure and sepsis are both associated with increased circulating levels of endotoxin and proinflammatory mediators and reduced levels of apoprotein-
Acton, Ali, Annane, Annane, Baranova, Beishuizen, Borkowski, Calco, Cicognani, Cooper, Darlington, Davies, de la Llera-Moya, Dimopoulou, Eisenberg, Ettinger, Gordon, Hamrahian, Harry, Hinshaw, Jaattela, Kilger, Liu, Liu, Liu, Liu, Loriaux, Marik, Marik, Marik, Marik, Marik, McDonald, Melby, Miyata, Molijn, Molijn, Mookerjee, Paul E. Marik, Rasaratnam, Rivers, Scammell, Singh, Sun, Thomas E. Starzl, Timothy Gayowski, van der Voort, van Leeuwen, Vishnyakova, Yaguchi, Yokoyama, Yokoyama   +51 more
core   +1 more source