Results 31 to 40 of about 204,387 (261)

Concomitant renal insufficiency and diabetes mellitus as prognostic factors for acute myocardial infarction

Cardiovascular Diabetology, 2011
Background Diabetes mellitus and renal dysfunction are prognostic factors after acute myocardial infarction (AMI). However, few studies have assessed the effects of renal insufficiency in association with diabetes in the context of AMI.
Kim Chang Seong, Choi Joon Seok, Park Jeong Woo, Bae Eun Hui, Ma Seong Kwon, Jeong Myung Ho, Kim Young Jo, Cho Myeong Chan, Kim Chong Jin, Kim Soo Wan   +9 more
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Life’s Essential 8 metrics and prognosis in patients with renal insufficiency: Results from the National Health and Nutrition Examination Survey, 2007–2018

Chinese Medical Journal
. Background:. The benefits of ideal cardiovascular-health metrics (ICVHMs) in patients with renal insufficiency remain unclear. This study aimed to investigate the associations between ICVHM and prognosis in a renal insufficiency population.
Weihua Chen, Guitao Xiao, Shan Ding, Shanshan Shi, Yuxiong Pan, Jiabin Tu, Yanbin Zhang, Ying Liao, Liling Chen, Kaihong Chen, Rongchong Huang, Yuanyuan Ji   +11 more
doaj   +1 more source

A rare and challenging renal transplant in a child with complex congenital defects - A case report

Indian Journal of Transplantation, 2021
Renal insufficiency is a distinct possibility in patients with congenital lower urinary tract abnormalities even though they are managed right from early childhood. Previously, such patients were not considered candidates for renal transplantation due to
Bharath N Kumar, Krishna V Baliga, Arjun Singh Sandhu   +2 more
doaj   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Drugs and renal insufficiency

Medicine, 2003
Abstract Renal insufficiency alters both the disposition of drugs in the body (pharmacokinetics) and tissue responses to drugs (pharmacodynamics); nephrotoxic drugs can impair renal function. This article should be read in conjunction with Raftery, page 100.
openaire   +2 more sources

Outcomes Following Coronary Artery Bypass Graft Surgery in Patients with Mild Preoperative Renal Insufficiency

Brazilian Journal of Cardiovascular Surgery
Introduction: Preoperative renal insufficiency is an independent predictor of mortality after coronary artery bypass graft (CABG) surgery. However, there are few reports aimed to evaluate the impact of mild preoperative renal insufficiency on long-term ...
Weitie Wang, Yuefeng Wang, Rihao Xu, Junwu Chai, Wei Zhou, Honglei Chen, Kai Wang, Xiangrong Kong   +7 more
doaj   +1 more source

Reversible Renal Insufficiency Secondary to Extrinsic Splenic Compression of the Kidney in a Patient with Chronic Lymphocytic Leukemia

The Scientific World Journal, 2010
While increased renal venous and direct renal parenchymal pressure may cause renal insufficiency, there are no prior reports of hypersplenism secondary to chronic lymphocytic leukemia (CLL) doing so.
Miriam Hadj-Moussa, James A. Brown
doaj   +1 more source

Association of high blood pressure with renal insufficiency: role of albuminuria, from NHANES, 1999-2006.

PLoS ONE, 2012
BackgroundThe relationship between hypertension and kidney disease is complicated. Clinical trials found intense blood pressure control was not associated with alterations in glomerular filtration rate (GFR) in all patients but did slow the rate of GFR ...
Ping Yan, Xiangzhu Zhu, Haiming Li, Martha J Shrubsole, Haiming Shi, Ming-zhi Zhang, Raymond C Harris, Chuan-Ming Hao, Qi Dai   +8 more
doaj   +1 more source

Indicators of acute and persistent renal damage in adult thrombotic microangiopathy. [PDF]

PLoS ONE, 2012
BACKGROUND: Thrombotic microangiopathies (TMA) in adults such as thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS) are life-threatening disorders if untreated.
Firuseh Dierkes, Nikolaos Andriopoulos, Christoph Sucker, Kathrin Kuhr, Markus Hollenbeck, Gerd R Hetzel, Volker Burst, Sven Teschner, Lars C Rump, Thomas Benzing, Bernd Grabensee, Christine E Kurschat   +11 more
doaj   +1 more source