Results 31 to 40 of about 214,404 (261)
Inflammation and Cardiovascular Disease Associated With Hemodialysis for End-Stage Renal Disease
Frontiers in Pharmacology, 2022 Chronic kidney disease (CKD) and cardiac insufficiency often co-exist, particularly in uremic patients on hemodialysis (HD). The occurrence of abnormal renal function in patients with cardiac insufficiency is often indicative of a poor prognosis.
Yinghui Wang, Lu Gao
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Medicine, 2003 Abstract Renal insufficiency alters both the disposition of drugs in the body (pharmacokinetics) and tissue responses to drugs (pharmacodynamics); nephrotoxic drugs can impair renal function. This article should be read in conjunction with Raftery, page 100.
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Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
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Chinese Medical Journal. Background:. The benefits of ideal cardiovascular-health metrics (ICVHMs) in patients with renal insufficiency remain unclear. This study aimed to investigate the associations between ICVHM and prognosis in a renal insufficiency population.
Weihua Chen +11 more
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A rare and challenging renal transplant in a child with complex congenital defects - A case report
Indian Journal of Transplantation, 2021 Renal insufficiency is a distinct possibility in patients with congenital lower urinary tract abnormalities even though they are managed right from early childhood. Previously, such patients were not considered candidates for renal transplantation due to
Bharath N Kumar +2 more
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FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
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Brazilian Journal of Cardiovascular SurgeryIntroduction: Preoperative renal insufficiency is an independent predictor of mortality after coronary artery bypass graft (CABG) surgery. However, there are few reports aimed to evaluate the impact of mild preoperative renal insufficiency on long-term ...
Weitie Wang +7 more
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The Scientific World Journal, 2010 While increased renal venous and direct renal parenchymal pressure may cause renal insufficiency, there are no prior reports of hypersplenism secondary to chronic lymphocytic leukemia (CLL) doing so.
Miriam Hadj-Moussa, James A. Brown
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PLoS ONE, 2012 BackgroundThe relationship between hypertension and kidney disease is complicated. Clinical trials found intense blood pressure control was not associated with alterations in glomerular filtration rate (GFR) in all patients but did slow the rate of GFR ...
Ping Yan +8 more
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Indicators of acute and persistent renal damage in adult thrombotic microangiopathy. [PDF]
PLoS ONE, 2012 BACKGROUND: Thrombotic microangiopathies (TMA) in adults such as thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS) are life-threatening disorders if untreated.
Firuseh Dierkes +11 more
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