Results 91 to 100 of about 209,959 (307)

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

open access: yesAdvanced Materials Technologies, EarlyView.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang   +4 more
wiley   +1 more source

Association between simple renal cyst and kidney damage in a Chinese cohort study

open access: yesRenal Failure, 2019
Background: The presence of simple renal cyst (SRC) has been associated to renal dysfunction, but the results were inconsistent. Accordingly, we conducted a longitudinal cohort study to explore the association between SRC and kidney damage.
Juan Chen   +4 more
doaj   +1 more source

Being adolescent with chronic renal failure: a view through existential phenomenology

open access: yesEscola Anna Nery, 2018
Objective: To understand adolescent's experiences with chronic renal failure disease, attended in a pubic teaching hospital at São Paulo state.
Marcela Astolphi de Souza   +1 more
doaj   +1 more source

The nurse of the Mediterranean [PDF]

open access: yes, 2010
During the First World War Malta did not take an active part in the fighting. Britain was joined in an ‘entente’ a friendship agreement with France since 1904 and later with Russia in 1907.
Pisani, Saviour
core  

Weekly irinotecan in a patient with metastatic colorectal cancer on hemodialysis due to chronic renal failure [PDF]

open access: yes, 2002
Background: The cytotoxic treatment of patients suffering from advanced or metastatic cancer undergoing hemodialysis due to chronic renal failure still remains a problem, since for those patients pharmacokinetic and pharmacodynamic data on most cytotoxic
Hacker, U.   +4 more
core   +1 more source

Annexin A13 Protects Against Acute Kidney Injury by Inactivating TGF‐β/Smad3 Signaling

open access: yesAdvanced Science, EarlyView.
ANXA13 is negatively regulated by Smad3 and exerts its protective role in AKI by inactivating TGF‐β/Smad3 signaling and Smad3‐p21 cell cycle arrest pathway through binding to TβRI, inhibiting the interaction between TβRI and TβRII, thereby suppressing TβRI phosporylation.
Jiaxiao Li   +12 more
wiley   +1 more source

The relationship between serum levels of LOX-1, hs-cTnT, NGAL, and renal function, and their diagnostic value in patients with chronic kidney disease: a retrospective study

open access: yesBMC Nephrology
Background The primary aim of this study is to explore the relationship between serum levels of LOX-1, hs-cTnT, and NGAL, and renal function in patients with CKD, as well as to evaluate their diagnostic value for early detection and monitoring of disease
Liyin Chai   +7 more
doaj   +1 more source

Partial nephrectomy for renal cell carcinoma: Operative steps

open access: yesJournal of the Scientific Society, 2017
Open partial nephrectomy (PN) is the standard technique for organ-sparing resection of renal tumors. PN traditionally was done (if technically possible) in patients with renal cell carcinoma in a solitary kidney, if bilateral tumors are present, in ...
Rajendra B Nerli   +4 more
doaj   +1 more source

Targeting Adipose Tissue Function Protects Against Heart Failure with Preserved Ejection Fraction

open access: yesAdvanced Science, EarlyView.
This study explores the role adipose tissue (AT) phenotypes have in determining cardiovascular outcomes in an obesity‐related heart failure with preserved ejection fraction (HFpEF) model. Pharmacological induction of thermogenesis promoted resilience to HFpEF‐induced remodeling of AT and conferred cardioprotection. Surgical and genetic models confirmed
Jordan Jousma   +11 more
wiley   +1 more source

Epidemiological clinical characterization of patients with advanced chronic kidney disease

open access: yesActa Médica del Centro, 2016
Chronic kidney disease is considered as one of the major epidemics of the XXI century and provides a significant burden of morbidity and mortality in the world; it is important to identify and modify the factors of risk that influence its progression. In
Lexis Caridad Ramírez Felipe   +3 more
doaj  

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