Results 111 to 120 of about 169,102 (267)

BLITZ‐HF: a nationwide initiative to evaluate and improve adherence to acute and chronic heart failure guidelines

open access: yesEuropean Journal of Heart Failure, Volume 24, Issue 11, Page 2078-2089, November 2022., 2022
Aims To assess adherence to guideline recommendations among a large network of Italian cardiology sites in the management of acute and chronic heart failure (HF) and to evaluate if an ad‐hoc educational intervention can improve their performance on several pharmacological and non‐pharmacological indicators.
Michele Massimo Gulizia   +197 more
wiley   +1 more source

Effect of Clinical History on Predictive Model Performance for Renal Complications of Diabetes [PDF]

open access: yesarXiv
Diabetes is a chronic disease characterised by a high risk of developing diabetic nephropathy, which, in turn, is the leading cause of end-stage chronic kidney disease. The early identification of individuals at heightened risk of such complications or their exacerbation can be of paramount importance to set a correct course of treatment.
arxiv  

Steerable Delivery Sheath for Optimized LAA Closure: First Experience and Procedural Outcomes

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background The new Amplatzer Steerable Delivery Sheath is a delivery system designed to improve ease‐of‐use and procedural results of left atrial appendage closure (LAAC). We aimed to compare procedural results after switching our LAAC program at a tertiary care center with the Amulet device to the Steerable Delivery Sheath, with a control ...
Matthias Mezger   +4 more
wiley   +1 more source

Impact of Coronary Calcification on Complete Revascularization in Patients With Acute Coronary Syndrome and Multivessel Disease

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Coronary calcification is a well‐known marker of atherosclerotic plaque burden and a determinant of stent under expansion with unfavorable long‐term outcomes. Aims This sub study of the randomized BIOVASC trial aimed to compare immediate complete revascularization (ICR) and staged complete revascularization (SCR) in patients with ...
William Camilleri   +10 more
wiley   +1 more source

Towards Interpretable End-Stage Renal Disease (ESRD) Prediction: Utilizing Administrative Claims Data with Explainable AI Techniques [PDF]

open access: yesarXiv
This study explores the potential of utilizing administrative claims data, combined with advanced machine learning and deep learning techniques, to predict the progression of Chronic Kidney Disease (CKD) to End-Stage Renal Disease (ESRD). We analyze a comprehensive, 10-year dataset provided by a major health insurance organization to develop prediction
arxiv  

Enhancing End Stage Renal Disease Outcome Prediction: A Multi-Sourced Data-Driven Approach [PDF]

open access: yesarXiv
Objective: To improve prediction of Chronic Kidney Disease (CKD) progression to End Stage Renal Disease (ESRD) using machine learning (ML) and deep learning (DL) models applied to an integrated clinical and claims dataset of varying observation windows, supported by explainable AI (XAI) to enhance interpretability and reduce bias.
arxiv  

Deep Learning-Based Quantitative Assessment of Renal Chronicity Indices in Lupus Nephritis [PDF]

open access: yesarXiv
Background: Renal chronicity indices (CI) have been identified as strong predictors of long-term outcomes in lupus nephritis (LN) patients. However, assessment by pathologists is hindered by challenges such as substantial time requirements, high interobserver variation, and susceptibility to fatigue.
arxiv  

Adrenal Crisis [PDF]

open access: yes, 2019
Glucocorticoid replacement therapy, available since the 1950s, has prolonged the survival of patients with adrenal insufficiency. However, adrenal crises, which are life-threatening medical emergencies, still develop in many affected patients.
Falhammar, Henrik   +2 more
core   +1 more source

Identification and Clinical Evaluation of Potential Biomarkers for Breast Cancer Resistance Protein (BCRP/ABCG2)

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Clinical inhibition and genetic variation of the Breast Cancer Resistance Protein (BCRP/ABCG2) efflux transporter can significantly influence drug exposure, highlighting the need for reliable BCRP functional biomarkers. This study aimed to identify and evaluate biomarkers predictive of BCRP function in humans.
Andrew M. Riselli   +16 more
wiley   +1 more source

Integrated Machine Learning and Survival Analysis Modeling for Enhanced Chronic Kidney Disease Risk Stratification [PDF]

open access: yesarXiv
Chronic kidney disease (CKD) is a significant public health challenge, often progressing to end-stage renal disease (ESRD) if not detected and managed early. Early intervention, warranted by silent disease progression, can significantly reduce associated morbidity, mortality, and financial burden.
arxiv  

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