Results 131 to 140 of about 437,204 (353)

Engineering Immunoregenerative Therapy via an Immunomodulatory Binary Pharmacology Hydrogel Depot for Prolonged Allograft Survival

Advanced Science, EarlyView.
An immunomodulatory hydrogel (iGEL) forms spontaneously upon subcutaneous injection, acting as a tissue‐adhesive depot. It releases anti‐rejection and regenerative agents in response to inflammation, suppressing T‐cell activity, promoting vascular repair, and restoring allograft function without systemic immunosuppression.
Ning Wang, Ruiqi Sun, Yang Fu, Zhonghan Wu, Xinyu Tong, Hong Tang, Wentao Zhao, Zhi Liang, Jintao Zheng, Yanan Guan, Ke Zhou, Penghong Song, Shusen Zheng, Hangxiang Wang, Haiyang Xie   +14 more
wiley   +1 more source

Urinary Peptide Levels in Patients with Chronic Renal Failure [PDF]

, 2010
Introduction: Peptide levels in urine are found to be decreased in renal failure. In the current study urinary peptide levels were determined in chronic renal failure (CRF) patients.
Supriya M, Phani, Nagaraj M, M, Supriya, Nagaraj M Phani, Kavya R, Mungli, Prakash, R, Kavya, Mungli Prakash   +7 more
core  

Clinicopathological analyses of aged nephrotic syndrome

Linchuang shenzangbing zazhi, 2015
Objective To understand the nephritic syndrome in the elderly.Methods Clinicopathological analyses were performed on 287 patients with nephritic syndrome.According to the pathological WHO 1995 glomerular disease classification standard classification ...
TAO Juan, HAO Li
doaj  

Targeting METTL3 Attenuates Thyroid Inflammatory Injury by Restoring Th17/Treg Balance through a YTHDC2‐m6A‐Dependent KDR/VEGFA Loop

Advanced Science, EarlyView.
METTL3‐mediated m6A modification stabilizes KDR/Kdr mRNA through YTHDC2, amplifying the VEGFA‐KDR feedback loop and disturbing Th17/Treg balance. This pathway promotes persistent inflammation and tissue damage in patients with AIT, and inhibiting the METTL3‐KDR axis effectively disrupts this circuit, alleviating thyroid tissue injury and disease ...
Qingyi Hu, Huan Liu, Anwen Ren, Zimei Tang, Jie Tan, Wen Yang, Jie Ming, Tao Huang   +7 more
wiley   +1 more source

The spatial analysis of diagnosed Chronic Kidney Disease in Nigeria: A case study of Edo State [PDF]

, 2012
The thesis explores the severity of diagnosed chronic kidney disease (CKD) with particular reference to its impact in Edo state, Nigeria. There has been a scarcity of studies on the prevalence and spatial patterns of CKD in developing countries even ...
Oviasu, Osaretin
core  

Creatinine clearance versus serum creatinine as a risk factor in cardiac surgery [PDF]

, 2003
Walter JA, Mortasawi A, Arnrich B, et al. Creatinine clearance versus serum creatinine as a risk factor in cardiac surgery. BMC Surgery. 2003;3(1): 4.BACKGROUND: Renal impairment is one of the predictors of mortality in cardiac surgery.
Mortasawi, Amir, Inez Frerichs, Albert, Alexander, Mortasawi Amir, Rosendahl Ulrich, Frerichs, Inez, Alexander Albert, Ulrich Rosendahl, Jürgen Ennker, Amir Mortasawi, Walter, Jörg, Arnrich, Bert, Rosendahl, Ulrich, Frerichs Inez, Albert Alexander, Arnrich Bert, Ennker Jürgen, Jörg Walter, Bert Arnrich, Walter, Jörg A., Walter Jörg, Ennker, Jürgen   +21 more
core   +2 more sources

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Relationship of Estimated GFR and Coronary Artery Calcification in the (CRIC) Chronic Renal Insufficiency Cohort Study

American Journal of Kidney Diseases, 2011
Background Coronary artery calcification (CAC) is associated with increased mortality risk in the general population. Although individuals with chronic kidney disease (CKD) are at markedly increased mortality risk, the incidence, prevalence, and ...
M. Budoff, D. Rader, M. Reilly, E. Mohler, J. Lash, Wei Yang, L. Rosen, M. Glenn, V. Teal, H. Feldman   +9 more
semanticscholar   +1 more source

Original paper LIPOPROTEIN METABOLISM ABNORMALITIES IN PATIENTS WITH CHRONIC RENAL INSUFFICIENCY [PDF]

, 2014
Summary: Patients with chronic renal insufficiency on hemodialysis develop lipoprotein abnormalities that may contribute to increased risk for atherosclerosis.
Zorica Nikoli, Slavica Spasi, Mirjana Jugovi   +2 more
core  

Chronic Renal Insufficiency in an Adolescent Male with Bilateral Urolithiasis: A Case Report [PDF]

, 2004
The rare case of a 15-year-old male adolescent with chronic renal insufficiency, bilateral hydronephrosis, and urolithiasis, is presented. Characteristic features included abdominal mass, delayed presentation, marked growth retardation and profound ...
Marchie, T, OM Ibadin, IE Woghiren, T Marchie, Ibadin, OM, Woghiren, IE   +5 more
core   +1 more source