Results 71 to 80 of about 169,102 (267)

Chronic renal transplantation: a model for the hyperhomocysteinemia of renal insufficiency

Atherosclerosis, 2001
Renal transplant recipients (RTR) are considered representative of patients with chronic renal insufficiency (CRI) in general with respect to both reduced, progressively declining renal function, and increased risk for cardiovascular disease (CVD). In accord with this argument, we hypothesized that total (t) plasma concentrations of the putatively ...
Paul König, Erich Kuen, Eberhard Ritz, Ulrich Neyer, Vedat Schwenger, Reginald Y. Gohh, Jacob Selhub, Peter Riegler, Johannes F.E. Mann, Florian Kronenberg, Günther Kraatz, Karl Lhotta, Andrew G. Bostom, Andrew G. Bostom, Werner Riegel, Gerhard A. Müller   +15 more
openaire   +4 more sources

STING Agonists and How to Reach Their Full Potential in Cancer Immunotherapy

Advanced Science, EarlyView.
STING agonists show promise in preclinical studies in boosting an anti‐tumor response using the immune system. However, different limitations remain, and future research is needed to better understand how STING activation impacts the tumor microenvironment, identify effective combination strategies, and determine the best tumor types for STING agonist ...
Laura Gehrcken, Christophe Deben, Evelien Smits, Jonas R.M. Van Audenaerde   +3 more
wiley   +1 more source

Arterial stiffening provides sufficient explanation for primary hypertension [PDF]

, 2013
Hypertension is one of the most common age-related chronic diseases and by predisposing individuals for heart failure, stroke and kidney disease, it is a major source of morbidity and mortality. Its etiology remains enigmatic despite intense research efforts over many decades.
arxiv   +1 more source

Hypothyroidism and nephrotic syndrome: why, when and how to treat [PDF]

, 2017
Hypothyroidism, characterised by low/normal free thyroxine (FT4) and free tri-iodothyronine (FT3) with elevated thyroid-stimulating hormone (TSH), is a well-known complication of nephrotic syndrome (NS).
Barbano, Biagio, Cianci, Rosario, Di Mario, Francesca, Gigante, Antonietta, Isidori, Andrea, Pofi, Riccardo, Rivoli, Laura, Rosato, Edoardo   +7 more
core   +1 more source

Nephrogenic systemic fibrosis risk and liver disease. [PDF]

, 2014
Objective. Evaluate the incidence of nephrogenic systemic fibrosis (NSF) in patients with liver disease in the peritransplant period. Materials and Methods. This IRB approved study retrospectively reviewed patients requiring transplantation for cirrhosis,
Chow, Daniel S, Escudero, Mark R, Finkelstone, Lee A, Hanna, Robert F, Lagana, Stephen M, Miloushev, Vesselin Z, Prince, Martin R   +6 more
core   +3 more sources

Sodium homeostasis in dogs with chronic renal insufficiency

Kidney International, 1982
Volume homeostasis in the fasting rate and 24-hr sodium balance are maintained in chronic renal insufficiency as a result of adaptations in the residual nephrons. This study evaluates the limitations to these adaptations and the dynamics of sodium excretion (UNaV) after an acute challenge with 100 mEq of sodium chloride in normal dogs (GFR 50 ml/min ...
David Jaffe, Jacques J. Bourgoignie, George Gavellas, Michael A. Kaplan   +3 more
openaire   +3 more sources

The impact of delayed adjuvant chemotherapy on survival in gastric cancer patients with and without preoperative chemotherapy

Annals of Gastroenterological Surgery, EarlyView.
Delayed initiation of adjuvant chemotherapy (AC) is associated with significantly poorer postoperative survival in patients with gastric cancer, irrespective of whether preoperative chemotherapy was administered. These findings emphasize the importance of timely AC initiation to improve long‐term outcomes in this patient population.
Masataka Shimonosono, Takaaki Arigami, Daisuke Matsushita, Yusuke Tsuruda, Ken Sasaki, Kenji Baba, Takao Ohtsuka   +6 more
wiley   +1 more source

Sparse Longitudinal Representations of Electronic Health Record Data for the Early Detection of Chronic Kidney Disease in Diabetic Patients [PDF]

arXiv, 2020
Chronic kidney disease (CKD) is a gradual loss of renal function over time, and it increases the risk of mortality, decreased quality of life, as well as serious complications. The prevalence of CKD has been increasing in the last couple of decades, which is partly due to the increased prevalence of diabetes and hypertension.
arxiv  

Establishment of a integrative multi-omics expression database CKDdb in the context of chronic kidney disease (CKD) [PDF]

, 2017
Complex human traits such as chronic kidney disease (CKD) are a major health and financial burden in modern societies. Currently, the description of the CKD onset and progression at the molecular level is still not fully understood.
Fernandes, Marco, Husi, Holger
core   +1 more source

Treatment of Hypertension in Chronic Renal Insufficiency.

Internal Medicine, 2000
Hypertension is the most common complication of chronic renal insufficiency (CRI) and it accelerates the rate of progression of most forms of CRI. Several large clinical trials have clearly demonstrated the efficacy of antihypertensive treatment for prevention of progression of renal failure.
openaire   +3 more sources