Results 91 to 100 of about 1,613,591 (292)

The Pathogenic Roles of Local Vitamin D Metabolism Defect in Valve Inflammation and Calcification

Advanced Science, EarlyView.
This study identifies the valvular interstitial cell populations responsible for valvular calcification induced by hyperphosphatemia and likely aging, uncovers local vitamin D metabolism defect‐induced inflammation as a critical pathogenic factor of calcific aortic valve disease, and highlights active vitamin D and ERK inhibitor as potential preventive
Ruichen Yang, Chong Han, Yangli Xie, Shoutao Qiu, Shaoyang Zhang, Jingjia He, Zejian Wang, Zhenlin Zhang, Huijuan Liu, Lin Chen, Baojie Li   +10 more
wiley   +1 more source

Orthotopic liver transplantation for fulminant and subacute hepatic failure [PDF]

, 1988
Fulminant and subacute hepatitis are conditions characterized by rapid liver failure, which can lead to death in 80 to more than 95% of the cases with medical supportive care only.
Iwatsuki, S, Starzl, TE, Stieber, AC
core  

Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism

Advanced Science, EarlyView.
Melanoma, an aggressive skin cancer, arises from dynamic interactions between genetic, environmental, and lifestyle factors. This review explores how age, gender, obesity, diet, exercise, smoking, alcohol, UV exposure, circadian rhythms, and medications influence melanoma risk and progression.
Hanbin Wang, Hengxiang Zhang, Yuqi Zhou, Chunying Li, Weinan Guo   +4 more
wiley   +1 more source

High fludarabine exposure and relationship with treatment-related mortality after nonmyeloablative hematopoietic cell transplantation. [PDF]

, 2011
Despite its common use in nonmyeloablative preparative regimens, the pharmacokinetics of fludarabine are poorly characterized in hematopoietic cell transplantation (HCT) recipients and exposure-response relationships remain undefined.
Brunstein, CG, Cao, Q, Green, KG, Jacobson, PA, Long-Boyle, JR, McGlave, PB, Miller, JS, Rogosheske, J, Wagner, JE, Weisdorf, DJ   +9 more
core   +1 more source

Clinical Study of Acute Renal Insufficiency after Pulmonary Resection [PDF]

, 1963
Chon Hyun Kim
openalex   +1 more source

Closed‐Loop Bioelectronic Artificial Pancreas Patch for Continuous Monitoring and Regulation of Blood Glucose in Diabetic Rats and Pigs

Advanced Science, EarlyView.
A closed‐loop bioelectronic artificial pancreas patch is presented for glucose monitoring and regulation. Utilizing transiently dissolvable microneedle arrays integrated with microtube arrays, the patch efficiently delivers insulin into interstitial fluid, eliminating the need for external long needles. In diabetic pigs, it demonstrates excellent blood
Yiqun Liu, Changxi Zhang, Lingyi Xu, Yuan Ma, Yuanyuan Ma, Ying Chen, Difei Lu, Le Ye, Li Yang, Yue Cui   +9 more
wiley   +1 more source

Further evidence for the involvement of EFL1 in a Shwachman-Diamond-like syndrome and expansion of the phenotypic features. [PDF]

, 2018
Recent evidence has implicated EFL1 in a phenotype overlapping Shwachman-Diamond syndrome (SDS), with the functional interplay between EFL1 and the previously known causative gene SBDS accounting for the similarity in clinical features. Relatively little
Bacino, Carlos A, Bonner, Melanie J, Butler, Megan W, Cope, Heidi, Frush, Donald P, Jiang, Yong-Hui, Lachman, Ralph S, Lee, Brendan, McCall, Chad M, McDonald, Marie T, Pena, Loren DM, Pendse, Avani A, Rothman, Jennifer A, Shashi, Vandana, Spillmann, Rebecca C, Stong, Nicholas, Tan, Queenie K-G, Undiagnosed Diseases Network, Walley, Nicole   +18 more
core  

HIFU‐Driven Targeted Pyroptosis Therapy in Basal‐Like Breast Cancer

Advanced Science, EarlyView.
This study presents a HIFU‐driven pyroptosis strategy for BLBC treatment. Combining HIFU with platelet‐membrane hybridized liposomes encapsulating mitoxantrone enhances tumor targeting and efficacy. The synergistic treatment modulates key epigenetic regulators and activates the pyroptotic pathway through ROS generation and inflammasome signaling ...
Xiaomin Su, Yang Wang, Xifeng Qin, Yaqiong Xiao, Boshu Ouyang, Lina Hu, Lin Kang, Ruizhe Xu, Ce Xu, Zanya Sun, Chenyu Sun, Huishu Guo, Zhiqing Pang, Shun Shen   +13 more
wiley   +1 more source

Nephrotoxicity of halogenated inhalational anaesthetics: Fictions and facts [PDF]

, 2002
Conzen, Peter F., Peter, Klaus, Reichle, Florian M.   +2 more
core   +1 more source

Acute renal insufficiency due to lymphomatous infiltration of the kidneys.Report of six cases [PDF]

, 1976
A Kanfer, Alain Vandew Alle, L Morel-Marogér, M J Feintuch, Jean–Daniel Sraer, J Roland   +5 more
openalex   +1 more source