Results 101 to 110 of about 1,613,591 (292)

Optimized Monothiol Thioredoxin Derivative (ORP100S) Protects In Vitro and In Vivo from Radiation and Chemotoxicity Without Promoting Tumor Proliferation

open access: yesAdvanced Science, EarlyView.
Native thioredoxin‐1 (TRX) stimulates proliferation and rescues stem cells and cancer cells from multiple stressors by suppressing p53 and inhibiting ferroptosis via GPX4/SLC7A11 upregulation mediated by enhanced KLF4 expression and p53 promoter binding.
Jian Wu   +18 more
wiley   +1 more source

Biotransformation of diflunisal and renal excretion of its glucuronides in renal insufficiency. [PDF]

open access: bronze, 1979
Roger K. Verbeeck   +5 more
openalex   +1 more source

A Serum‐Stable Antimicrobial Peptide‐Based Delivery Platform for Selective Treatment of Nontargetable and Chemoresistant Tumors

open access: yesAdvanced Science, EarlyView.
A modular antimicrobial‐peptide‐based therapeutic system integrating membrane‐targeted selectivity, a conformation‐driven polyethylene glycolylated blocker, and serum‐stabilizing N‐cap is developed. The optimized conjugate 270 shows potent, rapid killing of the desired tumor cells, high serum stability, low off‐target toxicity, and broad applicability,
Tianxing Liu   +12 more
wiley   +1 more source

The nurse of the Mediterranean [PDF]

open access: yes, 2010
During the First World War Malta did not take an active part in the fighting. Britain was joined in an ‘entente’ a friendship agreement with France since 1904 and later with Russia in 1907.
Pisani, Saviour
core  

Honeysuckle‐Derived Nanovesicles Regulate Gut Microbiota for the Treatment of Inflammatory Bowel Disease

open access: yesAdvanced Science, EarlyView.
This study explores honeysuckle‐derived nanovesicles (HNVs) for treating inflammatory bowel disease. Orally administered HNVs alleviates colitis in mice by repairing the gut barrier, reducing inflammation, and restoring a healthy gut microbiota.
Yuanyuan Wang   +11 more
wiley   +1 more source

Stratifying Risk for Renal Insufficiency Among Lithium-Treated Patients: An Electronic Health Record Study

open access: yesNeuropsychopharmacology, 2016
V. Castro   +8 more
semanticscholar   +1 more source

Nanocatalytic Neuroprotection and Neurological Recovery Post‐Traumatic Brain Injury

open access: yesAdvanced Science, EarlyView.
This study demonstrates that combining Ce0.7Zr0.3O2 nanozymes with nimodipine enhances neuroprotection after traumatic brain injury. The therapy reduces oxidative stress, neuronal apoptosis, and improves blood–brain barrier integrity, with nanozymes effective at low doses.
Xinjie Hong   +10 more
wiley   +1 more source

慢性腎臓病(chronic kidney disease: CKD)患者における細菌感染症入院に関わるリスクの検討 [PDF]

open access: yes, 2014
【Background】To date, it is unknown whether renal insufficiency is associated with increased morbidity from bacterial infections. The aim of this study is to evaluate the relationship between renal insufficiency and bacterial infection-related ...
井上 勉, 佐藤 貴彦, 鈴木 洋通
core  

Dosing and Pharmacokinetics of Polymyxin B in Patients with Renal Insufficiency

open access: yesAntimicrobial Agents and Chemotherapy, 2016
V. Thamlikitkul   +6 more
semanticscholar   +1 more source

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