Results 11 to 20 of about 1,562,141 (341)
Renal insufficiency and cancer treatments
Renal insufficiency has been shown to be highly prevalent in patients with cancer. This renal insufficiency has been reported to be associated with reduced overall survival and increased cancer-related mortality.
V. Launay-Vacher, N. Janus, G. Deray
semanticscholar +4 more sources
Glucose-induced down regulation of thiamine transporters in the kidney proximal tubular epithelium produces thiamine insufficiency in diabetes [PDF]
Increased renal clearance of thiamine (vitamin B1) occurs in experimental and clinical diabetes producing thiamine insufficiency mediated by impaired tubular re-uptake and linked to the development of diabetic nephropathy.
A Adaikalakoteswari+42 more
core +8 more sources
Despite excellent bactericidal effect, dosing adjustment of polymyxin B for patients with renal insufficiency and polymyxin B-related nephrotoxicity is still a major concern to clinicians.
Peile Wang+7 more
semanticscholar +1 more source
Renal Insufficiency and Failure
Abstract Renal impairment is a common complication of multiple myeloma. Chronic renal failure is classified according to glomerular filtration rate as estimated by the MDRD (modification of diet in renal disease) formula, while RIFLE (risk, injury, failure, loss and end-stage renal disease) and AKIN (acute renal injury network) criteria ...
Dimopoulos, Meletios A+1 more
openaire +7 more sources
Oncogenic mechanisms in renal insufficiency [PDF]
AbstractThe prevalence of both cancer and end-stage renal disease is increasing. In addition, medical advances have meant increased survival rates for both diseases. Many chemotherapeutics are renally excreted, and conversely, renal insufficiency promotes a pro-neoplastic state, including genitourinary and other cancers.
Simona Ruxandra Volovat+7 more
openaire +3 more sources
Binding of bromocresol green and bromocresol purple to albumin in hemodialysis patients [PDF]
BACKGROUND: Colorimetric albumin assays based on binding to bromocresol purple (BCP) and bromocresol green (BCG) yield different results in chronic kidney disease. Altered dye binding of carbamylated albumin has been suggested as a cause.
Delanghe, Joris+8 more
core +1 more source
Drugs and renal insufficiency [PDF]
Abstract Renal insufficiency alters both the disposition of drugs in the body (pharmacokinetics) and tissue responses to drugs (pharmacodynamics); nephrotoxic drugs can impair renal function. This article should be read in conjunction with Raftery, page 100.
openaire +3 more sources
How to improve drug dosing for patients with renal impairment in primary care - a cluster-randomized controlled trial [PDF]
Background: Patients with chronic kidney disease (CKD) are at increased risk for inappropriate or potentially harmful prescribing. The aim of this study was to examine whether a multifaceted intervention including the use of a software programme for the ...
Beyer, Martin+7 more
core +1 more source
Objectives As a screening index of diabetic kidney disease (DKD), urinary albumin/creatine ratio (UACR) is commonly used. However, approximately 23.3%-56.6% of DKD patients with estimated glomerular filtration rate (eGFR) < 60 ml/min per 1.73 m2 are ...
Ai-mei Li+7 more
semanticscholar +1 more source