Results 91 to 100 of about 1,116,431 (255)

Renal nerve activity and renal function during environmental stress in DOCA-NaCl rats

, 1986
The effects of a stressful environmental stimulus (air stress) on mean arterial pressure, heart rate, renal sympathetic nerve activity, and renal function were studied in conscious deoxycorticosterone acetate-sodium chloride (DOCA-NaCl) hypertensive ...
S. Jones, J. P. Koepke, G. F. DiBona
core   +1 more source

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

Advanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li, Jingyue Song, Kaili Ma, Shunan Tang, Shuqian Wang, Wenya Ji, Chen Lu, Ting Zhang, Huaping Zheng, Xiaowei Zheng, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Renal Sympathetic Vasomotion Monitoring as a Novel Method for Intraprocedural Feedback for Renal Denervation

Graduate Medical Education Research Journal, 2019
Mentor: Irving H. Zucker Program: Anesthesiology Background & Objectives: The sympathetic nervous system is a master regulator of homeostasis, and sympathetic dysfunction is implicated in the pathophysiology of cardiovascular, renal, and neurological ...
Peter Ricci Pellegrino, Alicia M. Schiller, Han-jun Wang, Yiannis S. Chatzizisis, Irving H. Zucker   +4 more
doaj   +1 more source

ROLE OF LEPTIN AND INSULIN IN ACTIVATING RENAL SYMPATHETIC NERVE IN HIGH FAT FED RABBITS

, 2012
ROLE OF LEPTIN AND INSULIN IN ACTIVATING RENAL SYMPATHETIC NERVE IN HIGH FAT FED ...
Geoff A Head (13426077), Sandra L Burke (11215347), Benjie Barzel (13426074), Kyungjoon Lim (3597620), James Armitage (13059060)   +4 more
core  

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

Advanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu, Xue Han, Heng Zhang, Chang Ye, Tianjiao Xia, Xiaoping Gu   +5 more
wiley   +1 more source

Renal Nerve Stimulation Predicted Blood Pressure-Lowering Responses to Percutaneous Renal Denervation. [PDF]

Circ Cardiovasc Interv, 2023
Huang HC, Pan HY, Wang TD.
europepmc   +1 more source

Postnatal development of the optic nerve in (C57BL x CBA)F1 hybrid mice:general changes in morphometric parameters [PDF]

, 1996
A morphometric analysis of the optic nerve in different age groups of (C57BL x CBA)F1 hybrid mice was carried out. Morphometric parameters examined were mean nerve cross-sectional area (csa), mean myelinated nerve fibre count, mean myelinated nerve fibre
Dangata, Y Y, Findlater, G S, Kaufman, M H   +2 more
core  

Reversing Macrophage Immunometabolic Dysfunction in Prolonged Infections Via a Glutaminolysis‐Fueled Restoration‐Based Hierarchically Selective Therapeutic System

Advanced Science, EarlyView.
A hierarchically selective immunotherapeutic nanoplatform, mGls@HEV‐MTP, selectively restores macrophage immunocompetence through GLS1‐mediated restoration of glutaminolysis‐fueled anaplerosis. Concurrently, it renders Staphylococcus aureus (S. aureus) more readily recognizable to the metabolically reprogrammed macrophages, thereby facilitating ...
Weinan Yang, Zihao An, Honglu Cai, Congsun Li, Jiaxuan Zou, Wushi Cui, Wentao Chen, Tao Zhang, Shicheng Wang, Zizhan Su, Jian Xiao, Tao Sun, Bin Hu, Min Cheng, Zhongru Gou, Jianbin Xu, An Liu, Haobo Wu   +17 more
wiley   +1 more source

Renal denervation attenuates cardiac inflammatory responses via the afferent renal-splenic nerve axis after myocardial ischemic injury

Journal of Translational Medicine
Background Inflammation and the nervous system play pivotal roles in cardiac remodeling after myocardial infarction (MI). Recent study showed renal denervation (RDN) could reduce cardiac inflammation, however, the specific mechanism remains unclear ...
Youming Zhang, Xiaotong Gao, Baowei Zhang, Yizhang Wu, Chunjiang Zhou, Jiaxi Xie, Xin Xie, Xiaorong Li, Bing Yang   +8 more
doaj   +1 more source

Catheter based renal sympathetic denervaton: treatment option for resistant hypertension

Journal of College of Medical Sciences-Nepal, 2012
Essential hypertension being a major public health problem with an atrocious toll. Furthermore resistant hypertension has increased morbidity and mortality in spite of using three or more antihypertensive medication, including one diuretic at their ...
BM Dhital, Ou Yang Mao, JP Deep, VK Rauniyar   +3 more
doaj   +1 more source