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Cardiovascular Effects of Afferent Renal Nerve Stimulation
Clinical and Experimental Hypertension. Part A: Theory and Practice, 1987Electrical stimulation of afferent renal nerves elicits an increase in arterial pressure and heart rate. The hypertensive response is presumably due to the widespread activation of the sympathetic nervous system leading to peripheral vasoconstriction.
A, Stella +4 more
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Renal Nerve Stimulation as Procedural End Point for Renal Sympathetic Denervation
Current Hypertension Reports, 2018Renal sympathetic denervation (RDN) as treatment option for hypertension has a strong rationale; however, variable effects on blood pressure (BP) have been reported ranging from non-response to marked reductions in BP. The absence of a procedural end point for RDN is one of the potential factors associated with the variable response.
Mark R de Jong, Annemiek F Hoogerwaard
exaly +3 more sources
Renal nerve stimulation for the treatment of neurocardiogenic syncope
Cardiovascular Revascularization Medicine, 2013Neurocardiogenic syncope is a common disorder resulting from a transient increase in vagal tone and central sympathetic withdrawal leading to varying degrees of vasodilation and bradycardia. Hence an effective treatment should address both the bradycardia and vasodilation.
Malini, Madhavan +3 more
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Effect of renal nerve stimulation on responsiveness of the rat renal vasculature
American Journal of Physiology-Renal Physiology, 2002When the renal nerves are stimulated with sinusoidal stimuli over the frequency range 0.04–0.8 Hz, low (≤0.4 Hz)- but not high (≥0.4 Hz)-frequency oscillations appear in renal blood flow (RBF) and are proposed to increase responsiveness of the renal vasculature to stimuli.
Gerald F, DiBona, Linda L, Sawin
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Ontogeny of renal hemodynamic response to renal nerve stimulation in sheep
American Journal of Physiology-Renal Physiology, 1987The renal hemodynamic response to direct electrical stimulation of renal nerves was studied in conscious and chronically instrumented fetal (130-142 days gestation; term 145 days), newborn (7-12 days postnatal), and adult nonpregnant sheep. Renal nerve stimulation (RNS) produced a significant decrease in renal blood flow (RBF) velocity and a ...
J E, Robillard +4 more
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Influence of renal sympathetic nerve stimulation on renal function in the primate
American Journal of Physiology-Renal Physiology, 1989In anesthetized Macaca fascicularis monkeys renal sympathetic nerves were stimulated electrically while changes in renal function were measured. The range of stimulation frequencies was 0.25-4.0 Hz. In the primate the stimulation threshold for changes in renal vascular resistance at a renal perfusion pressure of 100 mmHg was between 1 and 2 Hz ...
S F, Echtenkamp, P F, Dandridge
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Journal of Human Hypertension, 2019
Renal denervation (RDN) is a well-known innovative therapy for hypertension. However, the effects of global RDN on blood pressure (BP) lowering are quite variable. Insufficient and futile denervation is considered a major factor contributing to the variable results.
Kunyue, Tan +10 more
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Renal denervation (RDN) is a well-known innovative therapy for hypertension. However, the effects of global RDN on blood pressure (BP) lowering are quite variable. Insufficient and futile denervation is considered a major factor contributing to the variable results.
Kunyue, Tan +10 more
openaire +2 more sources
The effect of graded renal nerve stimulation on renal function in the anaesthetized rabbit
Comparative Biochemistry and Physiology Part A: Physiology, 1984The renal nerves of the rabbit were stimulated to cause less than 5, 9 or 22% reduction in renal blood flow. Glomerular filtration rate was reduced by 0, 3 and 11% respectively when the renal nerves were stimulated at these increasing rates. At low and moderate rates of renal nerve stimulation absolute and fractional sodium excretions were reduced by ...
I F, Hesse, E J, Johns
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Renal sympathetic nerve responses to somato-sensory nerve stimulation in normotensive rats
Journal of the Autonomic Nervous System, 1995Blood pressure, heart rate and renal sympathetic nerve activity were recorded in groups of chloralose/urethane-anaesthetised intact, vagotomised and carotid sinus denervated Wistar rats before and during bilateral somatic afferent nerve stimulation from 0.1 to 3.2 Hz.
G, Davis, E J, Johns
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Renal nerve stimulation restores tubuloglomerular feedback after acute renal denervation
Acta Physiologica Scandinavica, 1998Renal nerves play an important role in the setting of the sensitivity of the tubuloglomerular feedback (TGF) mechanism. We recently reported a time‐dependent resetting of TGF to a lower sensitivity 3–4 h after acute unilateral renal denervation (aDNX). This effect persisted after 1 week, but was then less pronounced.
J, Kurkus, C, Thorup, A E, Persson
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