Results 11 to 20 of about 885,585 (253)

Sympathetic nerve-derived ATP regulates renal medullary blood flow via vasa recta pericytes [PDF]

Frontiers in Physiology, 2013
Pericyte cells are now known to be a novel locus of blood flow control, being able to regulate capillary diameter via their unique morphology and expression of contractile proteins. We have previously shown that exogenous ATP causes constriction of vasa
Scott S Wildman
doaj   +2 more sources

Renal Nerves and CKD [PDF]

Journal of the American Society of Nephrology, 2012
A role for renal nerves in the regulation of renal function has been recognized since the time of Claude Bernard.[1][1] It has also been clear that renal nerves have an intimate relationship with many forms of experimental hypertension,[2][2] and surgical splancnicectomy, with consequent ...
openaire   +2 more sources

Role of α2-Adrenoceptors in Hypertension: Focus on Renal Sympathetic Neurotransmitter Release, Inflammation, and Sodium Homeostasis

Frontiers in Physiology, 2020
The kidney is extensively innervated by sympathetic nerves playing an important role in the regulation of blood pressure homeostasis. Sympathetic nerve activity is ultimately controlled by the central nervous system (CNS).
Lydia Hering, Masudur Rahman, Sebastian A. Potthoff, Lars C. Rump, Johannes Stegbauer   +4 more
doaj   +1 more source

Renal Denervation Reduced Ventricular Arrhythmia After Myocardial Infarction by Inhibiting Sympathetic Activity and Remodeling

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Ventricular arrhythmia after myocardial infarction is the most important risk factor for sudden cardiac death, which poses a serious threat to human health.
Wen‐hui Zhang, Qi‐na Zhou, Yan‐mei Lu, Yao‐dong Li, Ling Zhang, Jiang‐hua Zhang, Qiang Xing, Wen‐kui Lv, Xin‐chun Cheng, Ge‐ge Zhang, Xue‐sheng Wang, Qi Gu, Xue Lou, Buajier Guli, Bao‐peng Tang, Xian‐hui Zhou   +15 more
doaj   +1 more source

Reduced Renal Mass, Salt-Sensitive Hypertension Is Resistant to Renal Denervation

Frontiers in Physiology, 2018
Aim: Activation of the sympathetic nervous system is common in resistant hypertension (RHT) and also in chronic kidney disease (CKD), a prevalent condition among resistant hypertensives.
Ionut Tudorancea, Ionut Tudorancea, Ionut Tudorancea, Thomas E. Lohmeier, Barbara T. Alexander, Dragos Pieptu, Dragomir N. Serban, Radu Iliescu, Radu Iliescu, Radu Iliescu, Radu Iliescu   +10 more
doaj   +1 more source

c-Jun reprograms Schwann cells of injured nerves to generate a repair cell essential for regeneration. [PDF]

, 2012
The radical response of peripheral nerves to injury (Wallerian degeneration) is the cornerstone of nerve repair. We show that activation of the transcription factor c-Jun in Schwann cells is a global regulator of Wallerian degeneration.
Jenkins, Billy, Turmaine, Mark, Mirsky, Rhona, Quintes, Susanne, Wicher, GK, Chabrol, Elodie, Latouche, Morwena, Chabrol, E, Behrens, A, Mirsky, R, Woodhoo, Ashwin, Jenkins, B, Mitter, Richard, Quintes, S, Turmaine, M, Greensmith, L, Woodhoo, A, Mitter, R, Behrens, Axel, Raivich, Gennadij, Wicher, Grzegorz K.,, Latouche, M, Banerjee, Annbily, Arthur-Farraj, PJ, Wilton, DK, Banerjee, A, Rahman, Mary, Jessen, KR, Rahman, M, Greensmith, Linda, Raivich, G, Arthur-Farraj, Peter J., Wilton, Daniel K., Jessen, Kristjan R.   +33 more
core   +1 more source

Pulse Wave Velocity Predicts Response to Renal Denervation in Isolated Systolic Hypertension

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
Background Renal sympathetic denervation seems to be less effective as a treatment for hypertension in patients with isolated systolic hypertension, a condition associated with elevated central arterial stiffness.
Karl Fengler, Karl‐Philipp Rommel, Robert Hoellriegel, Stephan Blazek, Christian Besler, Steffen Desch, Gerhard Schuler, Axel Linke, Philipp Lurz   +8 more
doaj   +1 more source

Efferent pathways in sodium overload-induced renal vasodilation in rats. [PDF]

PLoS ONE, 2014
Hypernatremia stimulates the secretion of oxytocin (OT), but the physiological role of OT remains unclear. The present study sought to determine the involvement of OT and renal nerves in the renal responses to an intravenous infusion of hypertonic saline.
Nathalia O Amaral, Thiago S de Oliveira, Lara M Naves, Fernando P Filgueira, Marcos L Ferreira-Neto, Gerard H M Schoorlemmer, Carlos H de Castro, André H Freiria-Oliveira, Carlos H Xavier, Diego B Colugnati, Daniel A Rosa, Graziela T Blanch, Clayton L Borges, Célia M A Soares, Angela A S Reis, Sergio L Cravo, Gustavo R Pedrino   +16 more
doaj   +1 more source

THE ROLE OF RENAL NERVES IN VASOPRESSIN CONTROL IN A MODEL OF AUTOSOMAL RECESSIVE POLYCYSTIC KIDNEY DISEASE

, 2023
Autosomal Recessive Polycystic Kidney Disease (ARPKD) is a genetic disorder which frequently leads to kidney failure, often necessitating hemodialysis or kidney transplant.
Lynch, Hannah
core   +3 more sources

Role of Renal Sympathetic Nerves in GLP‐1 (Glucagon‐Like Peptide‐1) Receptor Agonist Exendin‐4‐Mediated Diuresis and Natriuresis in Diet‐Induced Obese Rats

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background The gut‐derived hormone GLP‐1 (glucagon‐like peptide‐1) exerts beneficial effects against established risk factors for chronic kidney disease.
Xuefei Liu, Kaushik P. Patel, Hong Zheng
doaj   +1 more source