Results 121 to 130 of about 532,354 (260)

Serum C3 as an early-warning biomarker for renal pathological progression in DKD

Frontiers in Immunology
ObjectiveTo investigate the association between serum complement component 3 (C3) levels and renal pathological injury across different estimated glomerular filtration rate (eGFR) strata in patients with diabetic kidney disease (DKD) and evaluate its ...
Donghong Ma, Donghong Ma, Senle Dai, Senle Dai, Tongtong Dai, Tongtong Dai, Dandan Wang, Dandan Wang, Xue Shan, Jiao Zhang, Jiao Zhang, Jingjing Shi, Yulong Hou, Wenchao Li, Wenchao Li, Minghao Guo   +15 more
doaj   +1 more source

Artificial intelligence in renal pathology: Current status and future. [PDF]

Biomol Biomed, 2023
Feng C, Liu F.
europepmc   +1 more source

High Humidity Exacerbates Psoriasiform Skin Disease Relapse by Increasing Tissue‐Resident Memory T Cells via Altering Skin Microbiota

Advanced Science, EarlyView.
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang, Yuchao Chen, Chuanjian Lu, Huazhen Liu, Fenglian Qin, Sisi Dai, Feifei Qiu, Haiming Chen, Weihui Lu, Jonathan S. Bromberg, Zhenhua Dai   +10 more
wiley   +1 more source

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

Advanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li, Tao Wang, Yuwen Zhong, Zhiming Wang, Wei Li, Zejian Wang, Xinyi Yang, Yu Qiao, Jianfeng Xiang, Wei Gu, Zishu Wang, Lei Sun, Feng Qian   +12 more
wiley   +1 more source

Parameters Affecting the Kidney Size in Individuals without Known Renal Pathology: an Ultrasonographic Study. [PDF]

Maedica (Bucur), 2023
Chaudhary P, Arora KK, Garg S, Patra A, Sahoo SS.   +4 more
europepmc   +1 more source

Determining cellular and biochemical function of a novel adhesion molecule in kidneys. [PDF]

, 2016
Acute kidney injury is an abrupt loss of kidney function that develops in short time with limited effective treatments other than kidney transplantation. We have identified TMIGD1 (Transmembrane immuno- globulin domain 1) as a novel receptor expressed in
Arafa, Emad
core   +1 more source

TEAD1 Enhances Exosome Secretion and Promotes Exosome‐Mediated Tissue Regeneration

Advanced Science, EarlyView.
TEAD1 functions as a crucial molecular switch regulating exosome secretion in various cell types. TEAD1 enhances exosome secretion by upregulating key proteins associated with exosome secretion, including RAB11, CD9, and SNAP23. This study reveals a novel role for TEAD1 in regulating exosome secretion and tissue regeneration, particularly in diabetic ...
Yan Pu, Yi Wan, Wenhao Shi, Bin Li, Haiyue Zhang, Jun Wu, Lingling Li, Wenjia Guo, Chen Ding, Wenjun Yang   +9 more
wiley   +1 more source

Artificial Intelligence-Assisted Renal Pathology: Advances and Prospects. [PDF]

J Clin Med, 2022
Wang Y, Wen Q, Jin L, Chen W.
europepmc   +1 more source

Discovery of H2 Receptor Antagonists as Colistin Enhancers by Targeting Acid Stress Response

Advanced Science, EarlyView.
This study identifies YqgB as a key target for restoring colistin susceptibility in mcr‐positive pathogens under acidic conditions by remodeling phospholipid composition and reducing LPS modification. Deep learning‐based screening reveals H2 receptor antagonists as novel colistin adjuvants. Further investigations indicate that ranitidine and famotidine
Jinju Cai, Mengping He, Jianya Luo, Shuang Zhou, Tengyue Zhang, Jianing Li, Zhiqiang Wang, Yuan Liu   +7 more
wiley   +1 more source

V-Set Immunoglobulin Domain-Containing Protein 4 as a Novel Serum Biomarker of Lupus Nephritis and Renal Pathology Activity. [PDF]

Arthritis Rheumatol, 2023
Tang C, Zhang S, Teymur A, Yang B, Nazir F, Cai Q, Saxena R, Olsen NJ, Mohan C, Wu T.   +9 more
europepmc   +1 more source