Results 111 to 120 of about 316,846 (352)
This review highlights emerging bioengineering strategies for treating neointimal hyperplasia in the peripheral vasculature, focusing on approaches that promote re‐endothelialization, modulate smooth muscle cell phenotype, reduce inflammation, mitigate oxidative stress, and optimize biomechanical compliance.
Nikita Wilson John+5 more
wiley +1 more source
Role of FXR in Renal Physiology and Kidney Diseases. [PDF]
Guo Y, Xie G, Zhang X.
europepmc +1 more source
The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo+11 more
wiley +1 more source
One of the most prevalent complications of pregnancy is preeclampsia, a hypertensive disorder which is a leading cause of maternal and perinatal morbidity and premature birth with no effective pharmacological intervention.
Eric M. George+4 more
doaj +1 more source
Editorial: Epigenetic, molecular and programming mechanisms of renal physiology and pathophysiology. [PDF]
Gomes GN+3 more
europepmc +1 more source
Kidney Stone Dissolution By Tetherless, Enzyme‐Loaded, Soft Magnetic Miniature Robots
Wireless magnetic robots are developed for kidney stone dissolution. The robots navigate through a urinary tract model from bladder and ureter to renal pelvis with the help of external magnetic fields. The filaments are loaded with urease enzyme which catalyzes urea to carbon dioxide and ammonia, thereby increasing pH to basic regime and supporting ...
Afarin Khabbazian+15 more
wiley +1 more source
TGFβ1 orchestrates renal fibrosis following Escherichia coli pyelonephritis [PDF]
Renal scarring after pyelonephritis is linked to long-term health risks for hypertension and chronic kidney disease. Androgen exposure increases susceptibility to, and severity of, uropathogenic Escherichia coli (UPEC) pyelonephritis and resultant ...
Collins, Christina A+5 more
core +1 more source
Heme oxygenases (HO-1; HO-2) catalyze conversion of heme to free iron, carbon monoxide, and biliverdin/bilirubin. To determine the effects of renal HO-1 induction on blood pressure and renal function, normal control rats (n=7) and hemin-treated rats (n=6)
Fady T. Botros+2 more
doaj +1 more source
The roles of hydrogen sulfide in renal physiology and disease states. [PDF]
Feng J, Lu X, Li H, Wang S.
europepmc +1 more source
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche+16 more
wiley +1 more source