Results 131 to 140 of about 3,239,906 (356)

The Apelin-APJ system: its role in renal physiology and potential therapeutic applications for renal disease

open access: yes, 2013
Introduction Apelin is a vasoactive peptide isolated as a selective endogenous ligand of orphan receptor, APJ, which was genetically identified to have closest identity to the angiotensin II type 1 (AT-1) receptor. Subsequent studies elucidated the roles
M. Nishida, K. Hamaoka
semanticscholar   +1 more source

A systematic review of kidney-on-a-chip-based models to study human renal (patho-)physiology [PDF]

open access: gold, 2023
Vivian V. T. Nguyen   +5 more
openalex   +1 more source

Cell Calcification Models and Their Implications for Medicine and Biomaterial Research

open access: yesAdvanced Healthcare Materials, EarlyView.
Calcification, is the process by which the tissues containing minerals are formed, occurring during normal physiological processes, or in pathological conditions. Here, it is aimed to give a comprehensive overview of the range of cell models available, and the approaches taken by these models, highlighting when and how methodological divergences arise,
Luke Hunter   +5 more
wiley   +1 more source

Renal denervation ameliorated salt-induced hypertension by improving cardiac work, cardiac enzyme and oxidative balance in Sprague-Dawley rats

open access: yesInternational Journal of Cardiology. Cardiovascular Risk and Prevention
Background: Hypertension is associated with cardiovascular dysfunction, dysregulation of the antioxidant system and alteration of the level of some enzymes in the metabolic pathway.
Abdullahi Adejare   +7 more
doaj   +1 more source

The role of hydrogen sulfide in renal system

open access: yesFrontiers in Pharmacology, 2016
Hydrogen sulfide (H2S) has gained recognition as the third gaseous signaling molecule after nitric oxide (NO) and carbon monoxide (CO). This review surveys the emerging role of H2S in mammalian renal system, with emphasis on both renal physiology and ...
Xu Cao, Jinsong Bian
doaj   +1 more source

Tubulointerstitial injury and proximal tubule albumin transport in early diabetic nephropathy induced by type 1 diabetes mellitus [PDF]

open access: yes, 2017
A decrease in the tubular expression of albumin endocytic transporters megalin and cubilin has been associated with diabetic nephropathy (DN), but there are no comprehensive studies to date relating early tubulointerstitial injury and the effect of the ...
Bahamonde, Javiera   +3 more
core  

A Human Kidney Tubuloid Model of Repeated Cisplatin‐Induced Cellular Senescence and Fibrosis for Drug Screening

open access: yesAdvanced Healthcare Materials, EarlyView.
Replicating aging and senescence‐related pathophysiological responses in kidney organoids remains a significant challenge. Human adult renal tubular organoid, tubuloids, are successfully developed recapitulating cellular senescence that is the central pathophysiological mechanism of chronic kidney disease (CKD).
Yuki Nakao   +20 more
wiley   +1 more source

Editorial: Sex differences in renal physiology. [PDF]

open access: yesFront Physiol, 2023
Singh P, Dutta SR, Sullivan JC.
europepmc   +1 more source

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

open access: yesAdvanced Healthcare Materials, EarlyView.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu   +18 more
wiley   +1 more source

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