Results 161 to 170 of about 3,116,502 (374)

Intrinsically Soft Implantable Electronics for Long‐term Biosensing Applications

open access: yesAdvanced Sensor Research, EarlyView.
Intrinsically soft implantable biosensors address the mechanical mismatch of conventional rigid implants, improving biocompatibility and stability. This review explores soft encapsulation matrices, stretchable conductors, implantation strategies, and chronic fixation techniques.
Su Hyeon Lee   +5 more
wiley   +1 more source

Pre-clinical xenotransplantation: physiology and pharmacy in human decedent and non-human primate models

open access: yesFrontiers in Transplantation
Non-human primates and decedent humans have emerged as the two principal translational models in xenotransplantation. Each model has differing advantages and drawbacks. In this manuscript, we will compare and contrast the relative strengths of each model,
Douglas J. Anderson, Jayme E. Locke
doaj   +1 more source

Cost‐Effective Hierarchical Cobalt Nanostructured Laser‐Induced Graphene for Enhanced Uric Acid Detection

open access: yesAdvanced Sensor Research, EarlyView.
A one‐step electrochemical strategy is utilized to develop a flexible, enzyme‐free biosensor for the sensitive detection of uric acid (UA). The hierarchical cobalt nanostructures synergistically enhance the performance of the biosensor, resulting in a broad detection range of 5 to 700 µM with a sensitivity of 6.75 µA µM−1 cm−2 and a low detection limit
Anju Joshi, Gymama Slaughter
wiley   +1 more source

Non‐Invasive Diagnosis of Chronic Myocardial Infarction via Composite In‐Silico‐Human Data Learning

open access: yesAdvanced Science, EarlyView.
This study presents a non‐invasive machine learning model to identify infarct regions in the left ventricle using cardiac strain data. By combining rodent‐based simulated data with limited human data, the model achieves high accuracy in predicting infarct size and location without the need for gadolinium contrast agents, offering a promising ...
Rana Raza Mehdi   +7 more
wiley   +1 more source

Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy

open access: yesAdvanced Science, EarlyView.
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao   +12 more
wiley   +1 more source

Store-operated calcium entry: Pivotal roles in renal physiology and pathophysiology. [PDF]

open access: yesExp Biol Med (Maywood), 2021
Chaudhari S   +4 more
europepmc   +1 more source

HIC1 suppresses Tumor Progression and Enhances CD8+ T Cells Infiltration Through Promoting GSDMD‐induced Pyroptosis in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
These findings elucidate the innovative role of HIC1 as a transcriptional activator in GC, driving the initiation of pyroptosis and enhancing CD8+ T cell infiltration, which has certain novelty and creative significance. Collectively, targeting HIC1 can present an appealing immunotherapeutic strategy to improve outcomes in GC patients.
Mengjie Kang   +4 more
wiley   +1 more source

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