Results 181 to 190 of about 3,116,502 (374)
Post‐Translational Modifications in Cilia and Ciliopathies
This review synthesizes current understanding of post‐translational modifications (PTMs) in ciliary proteins and emphasizes their roles in ciliary formation, homeostasis, and signaling. This review also discusses the implication of PTM dysregulation in ciliopathies and explores therapeutic strategies targeting PTM‐modifying enzymes.
Jie Ran, Jun Zhou
wiley +1 more source
Physiological and pharmacological studies on the renal function in rats. (Report 2)
Hiroyasu Yamazoe
openalex +2 more sources
2002 AstraZeneca Young Investigator Award for Excellence in Renal Physiology Recipient [PDF]
Jonathan Barasch, Eladio A. Nunez
openalex +1 more source
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao+17 more
wiley +1 more source
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang+9 more
wiley +1 more source
Physiological role for P2X1 receptors in renal microvascular autoregulatory behavior [PDF]
Edward W. Inscho+4 more
openalex +1 more source
Dipyridamole Acts as Clinical Ferroptosis Inhibitor to Prevent from Tissue Injury
Dipyridamole acts as a clinically used compound to suppress ferroptosis. Dipyridamole down‐regulates the expression of RNF126, which is an E3 ligase to ubiquitinate SLC7A11 for proteasome degradation. The deficiency of SLC7A11 largely abolishes the protective role of dipyridamole both in vitro and in vivo.
Xiao Zhuang+22 more
wiley +1 more source
Frontiers in Renal and Epithelial Physiology – Grand Challenges
Douglas C Eaton
doaj +1 more source