Results 11 to 20 of about 3,116,502 (374)

3D Proximal Tubule Tissues Recapitulate Key Aspects of Renal Physiology to Enable Nephrotoxicity Testing. [PDF]

open access: yesFront Physiol, 2017
Due to its exposure to high concentrations of xenobiotics, the kidney proximal tubule is a primary site of nephrotoxicity and resulting attrition in the drug development pipeline.
King SM   +10 more
europepmc   +2 more sources

Teaching renal physiology in the 21st century: focus on acid-base physiology. [PDF]

open access: yesClin Kidney J, 2016
A thorough understanding of renal physiology, and in particular acid–base physiology, is essential for an understanding of nephrology. Difficulties in both teaching and learning this material are major impediments to attracting medical trainees into ...
Leehey DJ, Daugirdas JT.
europepmc   +2 more sources

Renal phosphate handling: Physiology

open access: yesIndian Journal of Endocrinology and Metabolism, 2013
Phosphorus is a common anion. It plays an important role in energy generation. Renal phosphate handling is regulated by three organs parathyroid, kidney and bone through feedback loops.
Narayan Prasad, Dharmendra Bhadauria
doaj   +3 more sources

A new CJASN series: Renal physiology for the clinician.

open access: yesClin J Am Soc Nephrol, 2014
With this issue, CJASN begins a new series of review articles designed to reconnect clinical nephrologists and trainees with the fundamentals of renal physiology and pathophysiology.
Zeidel ML, Hoenig MP, Palevsky PM.
europepmc   +2 more sources

Exploring student preferences with a Q-sort: the development of an individualized renal physiology curriculum.

open access: yesAdv Physiol Educ, 2015
Medical education reform is underway, but the optimal course for change has yet to be seen. While planning for the redesign of a renal physiology course at the Duke School of Medicine, the authors used a Q-sort survey to assess students' attitudes and ...
Roberts JK   +4 more
europepmc   +2 more sources

Disturbances of Renal Physiology [PDF]

open access: bronzeProceedings of the Royal Society of Medicine, 1957
Angela Lewis
openalex   +4 more sources

Tolvaptan as a tool in renal physiology.

open access: yesAm J Physiol Renal Physiol, 2014
For decades, the Brattleboro rat has been a useful model in kidney physiology. These animals manifest central diabetes insipidus (lack of circulating vasopressin) due to a mutation in the vasopressin-neurophysin gene.
Miranda CA, Lee JW, Chou CL, Knepper MA.
europepmc   +2 more sources

Claudins in renal physiology and disease [PDF]

open access: greenPediatric Nephrology, 2011
The tight junction forms the paracellular permeability barrier in all epithelia, including the renal tubule. Claudins are a family of tight junction membrane proteins with four transmembrane domains that form the paracellular pore and barrier. Their first extracellular domain appears to be important for determining selectivity.
Jiahua Li   +2 more
openalex   +4 more sources

The role of adiponectin in renal physiology and development of albuminuria [PDF]

open access: bronzeJournal of Endocrinology, 2014
Adiponectin is secreted by the adipose tissue and is downregulated in states of obesity and insulin resistance. There is a growing body of evidence indicating that adiponectin has renoprotective effects and protects against the development of albuminuria
Georgios A. Christou   +1 more
openalex   +2 more sources

The autonomic nervous system and renal physiology [PDF]

open access: yesInternational Journal of Nephrology and Renovascular Disease, 2013
John A D'Elia,1,2 Larry A Weinrauch1,2 1Joslin Diabetes Center, Beth Israel Deaconess Medical Center, Boston, MA, USA; 2Department of Medicine, Harvard Medical School, Boston, MA, USA Abstract: Research in resistant hypertension has again focused on ...
D'Elia JA, Weinrauch LA
doaj   +2 more sources

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