Results 11 to 20 of about 316,846 (352)
Sex Differences in Renal Function: Participation of Gonadal Hormones and Prolactin
Endocrines, 2021 Kidney pathophysiology is influenced by gender. Evidence suggests that kidney damage is more severe in males than in females and that sexual hormones contribute to this.
Adriana Franco-Acevedo +2 more
doaj +1 more source
Early type 1 diabetes aggravates renal ischemia/reperfusion-induced acute kidney injury
Scientific Reports, 2021 The present study aimed to investigate the interaction between early diabetes and renal IR-induced AKI and to clarify the mechanisms involved. C57BL/6J mice were assigned to the following groups: (1) sham-operated; (2) renal IR; (3) streptozotocin (STZ ...
Mariana Charleaux de Ponte +4 more
doaj +1 more source
Maternal fructose intake during pregnancy and lactation: Later effects on renal function
Physiological Reports, 2022 Excessive fructose consumption has been associated with hypertension and metabolic disorders and can alter physiological adaptations during pregnancy, with long‐term detrimental consequences.
Leticia M. Monteiro +4 more
doaj +1 more source
Requirement for a Uroplakin 3a-like protein in the development of zebrafish pronephric tubule epithelial cell function, morphogenesis, and polarity [PDF]
, 2012 Uroplakin (UP)3a is critical for urinary tract development and function; however, its role in these processes is unknown. We examined the function of the UP3a-like protein Upk3l, which was expressed at the apical surfaces of the epithelial cells that ...
Chiara Cianciolo Cosentino +8 more
core +12 more sources
Physiology of the Renal Interstitium [PDF]
Clinical Journal of the American Society of Nephrology, 2015 Long overlooked as the virtual compartment and then strictly characterized through descriptive morphologic analysis, the renal interstitium has finally been associated with function. With identification of interstitial renin- and erythropoietin-producing cells, the most prominent endocrine functions of the kidney have now been attributed to the renal ...
Zeisberg, Michael, Kalluri, Raghu
openaire +4 more sources
Acclimation to a High‐Salt Diet Is Sex Dependent
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background Premenopausal women are less likely to develop hypertension and salt‐related complications than are men, yet the impact of sex on mechanisms regulating Na+ homeostasis during dietary salt challenges is poorly defined.
Eman Y. Gohar +14 more
doaj +1 more source
Pharmaceuticals, 2023 Long-lasting hyperglycaemia may alter the role of adenosine-dependent receptors (P1R) in the control of kidney function. We investigated how P1R activity affects renal circulation and excretion in diabetic (DM) and normoglycaemic (NG) rats; the receptors’
Joanna Dorota Sitek +4 more
doaj +1 more source
Sphingosine 1-phosphate in renal diseases [PDF]
, 2013 Because of its highly bioactive properties sphingosine 1-phosphate (S1P) is an attractive target for the treatment of several diseases. Since the expression of sphingosine kinases as well as S1P receptors was demonstrated in the kidney, questions about ...
Huwiler, Andrea +2 more
core +5 more sources
Early life stress induces dysregulation of the heme pathway in adult mice
Physiological Reports, 2021 Early life stress (ELS) is associated with cardiovascular disease (CVD) risk in adulthood, but the underlying vascular mechanisms are poorly understood.
Yasminye D. Pettway +9 more
doaj +1 more source
Frontiers in Medicine, 2020 Alterations in the renal vasculature during fetal programming can cause disturbances in renal structure and function that persist into adulthood. Calcitriol can affect cellular differentiation and proliferation, and promote endothelial cell maintenance ...
Amanda L. Deluque +6 more
doaj +1 more source