Results 201 to 210 of about 316,846 (352)

Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy

open access: yesAdvanced Science, EarlyView.
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao   +12 more
wiley   +1 more source

Processing and clearance of atrial natriuretic factor [PDF]

open access: yes, 1991
Gerbes, Alexander L.   +2 more
core   +1 more source

American Journal of Physiology-Renal Physiology Collections: Hypertension.

open access: yesAm J Physiol Renal Physiol, 2020
Klemens CA, Staruschenko A.
europepmc   +1 more source

USP10 Inhibits Ferroptosis via Deubiquinating POLR2A in Head and Neck Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
This study identifies USP10 as a novel deubiquitinase that antagonizes ferroptosis in head and neck squamous cell carcinoma (HNSCC). Mechanistically, USP10 directly stabilizes POLR2A protein through post‐translational deubiquitination, enabling POLR2A‐mediated transcriptional activation of SLC7A11, a key ferroptosis inhibitor.
Diekuo Zhang   +13 more
wiley   +1 more source

The carotid body as a therapeutic target for the treatment of sympathetically mediated diseases [PDF]

open access: yes, 2013
Abdala, Ana P   +13 more
core   +1 more source

Spice Up Your Kidney: A Review on the Effects of Capsaicin in Renal Physiology and Disease. [PDF]

open access: yesInt J Mol Sci
Musolino M   +5 more
europepmc   +1 more source

IncRNA‐ZFAS1, an Emerging Gate‐Keeper in DNA Damage‐Dependent Transcriptional Regulation

open access: yesAdvanced Science, EarlyView.
LncZFAS1 plays a crucial role during DNA damage response in mammalian cells. Loss of lncZFAS1 results in deficient DNA lesion removal and reduced cell viability. Mechanistically, lncZFAS1 modulates RNAPII phosphorylation and transcription and thereby promotes both GG‐NER and TC‐NER upon UV damage.
Jiena Liu   +10 more
wiley   +1 more source

The Renal Physiology of Pendrin-Positive Intercalated Cells.

open access: yesPhysiol Rev, 2020
Wall SM, Verlander JW, Romero CA.
europepmc   +1 more source

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