Results 211 to 220 of about 3,116,502 (374)

Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis

Advanced Science, EarlyView.
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu, Shengyu Jin, Xin Fu, Chong Xie, Yi Chen, Liangtang Chang, Yongheng Fan, Donghua He, Xiaoqi Hong, Xi Shen, Xiaoli Zheng, Qiyue Wang, Dao Shi, Fangyuan Li, Daishun Ling, Yangtai Guan, Neng Gong, Xiaoping Tong   +17 more
wiley   +1 more source

Transcription factor specificity protein (SP) family in renal physiology and diseases. [PDF]

PeerJ
Zhou W, Fang J, Jia Q, Meng H, Liu F, Mao J.   +5 more
europepmc   +1 more source

Renal albumin absorption in physiology and pathology [PDF]

, 2006
Henrik Birn, E. Christensen
openalex   +1 more source

In Situ Valence Engineering of Copper Silicate Nanozymes with Enhanced Peroxidase‐Like Catalytic Activity for Oral Disease Detection

Advanced Science, EarlyView.
A novel copper silicate nanozyme (CSHSs‐Ar) with high peroxidase‐like catalytic activity and great catalytic specificity is well developed using a facile in situ valence‐engineered approach. The well‐developed CSHSs‐Ar nanozyme‐involved system can be utilized and employed as an efficient colorimetric sensor for the detection of volatile sulfur ...
Xiaocan Liu, Zhen Ding, Chengjing Xu, Jinming Zhang, Yufu Liu, Tianyan Chen, Shuang Dai, Xingfu Bao, Min Hu, Zhen Liu   +9 more
wiley   +1 more source

HNF1B Transcription Factor: Key Regulator in Renal Physiology and Pathogenesis. [PDF]

Int J Mol Sci
Sánchez-Cazorla E, Carrera N, García-González MÁ.   +2 more
europepmc   +1 more source

Takis Anagnostopoulos Symposium: Renal and Epithelial Physiology and Pathophysiology [PDF]

, 2006
Moritoki Egi, Christoph Langenberg, Rinaldo Bellomo, Sangeeta Pande, Cynthia S. Ritter, Marcos Rothstein, Karen Wiesen, John Vassiliadis, Rajiv Kumar, Susan C. Schiavi, Eduardo Slatapolsky, Alex J. Brown, Kai M. Schmidt‐Ott, Debin Lan, Benjamin J. Hirsh, Jonathan Barasch, Clive N. May, Wan Li, Stanislao Morgera, Hiroshi Kamijo, Makoto Higuchi, Kazuhiko Hora, Ewout J. Hoorn, Jason D. Hoffert, Mark A. Knepper   +24 more
openalex   +1 more source

Magnetite Micro/Nanorobots for Efficient Targeted Alleviation of Inflammatory Bowel Disease

Advanced Science, EarlyView.
Improved reactive oxygen species scavenging capacities of functionalized micro/nanorobots (MNRs) are useful for the treatment of inflammatory bowel disease (IBD). MNRs can break the harmful bacteria in IBD, thereby eliminating inflammation and restoring the intestinal barrier function.
Ying Feng, Yang Liu, Linlin Liu, Qian Yang, Miao An, Huaming Yang   +5 more
wiley   +1 more source

Renal Physiology Education via Podcast: Channel Your Enthusiasm. [PDF]

Kidney Med
Hoenig MP, Gaddy AR, Meena P, Rodby RA, Rolón L, Velez JCQ, Waitzman J, Yau AA, Topf JM.   +8 more
europepmc   +1 more source

Role of the extracellular cAMP-adenosine pathway in renal physiology

, 2001
Edwin K. Jackson, Raghvendra K. Dubey
openalex   +1 more source

USP8‐Governed MDA5 Homeostasis Promotes Innate Immunity and Autoimmunity

Advanced Science, EarlyView.
This study reveals that USP8 stabilizes MDA5 via AKT‐mediated phosphorylation (Ser718), enhancing their interaction and MDA5 deubiquitination. USP8 inactivation degrades MDA5, suppressing type I IFN and cytokine production. Pharmacological inhibition of USP8/AKT alleviates MDA5‐driven autoimmunity, demonstrating the USP8‐MDA5 axis as a therapeutic ...
Qimin Zhang, Shan Huang, Yan He, Weiwei Wang, Chao Tong, Mengru Ma, Manyu Zhao, Lian Yi, Klaus‐Peter Knobeloch, Peijing Zhang   +9 more
wiley   +1 more source