Results 211 to 220 of about 3,239,906 (356)

The role of pendrin in renal physiology.

open access: yesAnnual Review of Physiology, 2015
S. Wall, Yoskaly Lazo-Fernandez
semanticscholar   +1 more source

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

open access: yesAdvanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li   +17 more
wiley   +1 more source

Renal Physiology Education via Podcast: Channel Your Enthusiasm. [PDF]

open access: yesKidney Med
Hoenig MP   +8 more
europepmc   +1 more source

Cosmic kidney disease: an integrated pan-omic, physiological and morphological study into spaceflight-induced renal dysfunction.

open access: green
Keith Siew   +99 more
openalex   +2 more sources

Development of Physiologically Based Pharmacokinetic Model and Assessment of the Impact of Renal Underdevelopment in Preterm Infants on the Pharmacokinetics of Aminophylline

open access: hybrid, 2022
Hari Prabhath Tummala   +7 more
openalex   +1 more source

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

open access: yesAdvanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li   +11 more
wiley   +1 more source

Editorial: Renal physiology: epithelial cell mechanics. [PDF]

open access: yesFront Physiol
Di Sole F, Laghmani K, Babich V.
europepmc   +1 more source

Natriuretic Peptide Receptor Guanylyl Cyclase-A in Podocytes is Renoprotective but Dispensable for Physiologic Renal Function [PDF]

open access: bronze, 2016
Janina Staffel   +8 more
openalex   +1 more source

De Novo Gene Transcription of Connexin Mediates Cytoplasmic Fluid Exchange and Flocking Transitions in Physiological and Cancerous Epithelial Systems

open access: yesAdvanced Science, EarlyView.
EGF‐induced de novo transcription of connexins Cx26 and Cx31 promotes flocking behavior that fluidizes epithelia and enables coordinated collective migration. Connexin‐driven cytoplasmic exchange mechanistically links growth‐factor signaling to invasive dynamics.
Hind Abdo   +18 more
wiley   +1 more source

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