Results 231 to 240 of about 3,116,502 (374)

Physiology and pathophysiology of the vasopressin-regulated renal water reabsorption [PDF]

, 2008
Michelle Boone, Peter M.T. Deen
openalex   +1 more source

Astrocytic ET‐1 System Determines Microglia Phenotype Following Spinal Cord Injury

Advanced Science, EarlyView.
The study reveals that astrocytic ET‐1 system is solely activated by thrombin following SCI via RhoA/NF‐κB and MAPKs/NF‐κB signal pathway. The release of astrocytic ET‐1 drives microglia polarization toward M1 phenotype through YAP signaling via ETA and ETB receptors.
Bingqiang He, Si Xu, Mengdi Li, Hui Li, Shaolan Li, Li Niu, Honghua Song, Rixin Cai, Yue Zhou, Zhilong Cao, Yingjie Wang, Yongjun Wang   +11 more
wiley   +1 more source

Spice Up Your Kidney: A Review on the Effects of Capsaicin in Renal Physiology and Disease. [PDF]

Int J Mol Sci
Musolino M, D'Agostino M, Zicarelli M, Andreucci M, Coppolino G, Bolignano D.   +5 more
europepmc   +1 more source

Is there a gender difference in antidiuretic response to desmopressin in children? [PDF]

, 2013
De Bruyne, Pauline, Goble, Sandra, Nørgaard, Jens Peter, Vande Walle, Johan, Vinter, Kristiaan Juul   +4 more
core   +1 more source

Exploring Potentially Inappropriate Medication Use on Elderly Patients in a General Medicine Ward Using 2023 AGS Beers Criteria

AGING MEDICINE, EarlyView.
This study found that 54% of elderly inpatients were prescribed at least one potentially inappropriate medication (PIM) based on the 2023 AGS Beers Criteria. Among identified PIMs, 32.2% were medications to avoid, and 52.8% required cautious use. Polypharmacy and chronic kidney disease (CKD) were key predictors of PIM use.
Subash Karki, Rahi Bikram Thapa, Rajeev Shrestha   +2 more
wiley   +1 more source

Long‐Term Nutritional Benefits of Laparoscopic Pancreatoduodenectomy Over Open Surgery

Annals of Gastroenterological Surgery, EarlyView.
Minimally invasive laparoscopic pancreaticoduodenectomy (LPD) significantly improves long‐term nutritional outcomes compared to open pancreaticoduodenectomy (OPD). LPD patients demonstrated better preservation of muscle mass index (PMI) and a lower incidence of postoperative fatty liver.
Koki Kurahashi, Takayuki Anazawa, Kei Yamane, Kazuyuki Nagai, Satoshi Ishida, Satoshi Ogiso, Yoichiro Uchida, Takashi Ito, Takamichi Ishii, Etsuro Hatano   +9 more
wiley   +1 more source

Immunostimulatory DNA Tetrahedron‐Based Nanovaccine Combined With Immune Checkpoint PD‐1 Blockade for Boosting Systemic Immune Responses Against Oral Squamous Cell Carcinoma

Aggregate, EarlyView.
This study introduces an immunomodulatory DNA tetrahedral framework nucleic acid‐based nanovaccine tFNA‐CpG. The functionalized nanovaccine shows stable and well‐defined morphological characteristics and can be efficiently taken up by APCs. When combined with the immune checkpoint inhibitor anti‐PD‐1, it notably ameliorated the immunosuppressive ...
Xueting Yang, Yun Wang, Yan Yang, Sicheng Zhang, Dianri Wang, Yi Luo, Chunyan Shui, Yongcong Cai, Ruoyi Yang, Shuang Dong, Mu Yang, Yunfeng Lin, Chao Li   +12 more
wiley   +1 more source

Endocannabinoid System and the Kidneys: From Renal Physiology to Injury and Disease. [PDF]

Cannabis Cannabinoid Res, 2019
Chua JT, Argueta DA, DiPatrizio NV, Kovesdy CP, Vaziri ND, Kalantar-Zadeh K, Moradi H.   +6 more
europepmc   +1 more source

Renal and cardiorespiratory effects of treatment with lactated Ringer's solution or physiologic saline (0.9% NaCl) solution in cats with experimentally induced urethral obstruction [PDF]

, 2010
Marina G. M. C. M. Cunha, Gabrielle Coelho Freitas, Adriano Bonfim Carregaro, Kléber Gomes, Joäo P M. C. M. Cunha, Diego Vilibaldo Beckmann, Ney Luís Pippi   +6 more
openalex   +1 more source

Hypoferremic Response to Chronic Inflammation Is Controlled via the Hemojuvelin/Hepcidin/Ferroportin Axis and Does Not Involve Hepcidin‐Independent Regulation of Fpn mRNA

American Journal of Hematology, EarlyView.
ABSTRACT The iron regulatory hormone hepcidin contributes to the pathogenesis of anemia of inflammation (AI) by inhibiting the iron exporter ferroportin in target cells, causing hypoferremia. Under acute inflammation, hepcidin induction requires hemojuvelin (Hjv), a bone morphogenetic protein co‐receptor, while Fpn mRNA is also suppressed in a hepcidin‐
Siqi Liu, Sofiya Tsyplenkova, Carine Fillebeen, Kostas Pantopoulos   +3 more
wiley   +1 more source