Results 251 to 260 of about 3,239,906 (356)
BK and JC Virus Infections in Renal Failure: A Meta-Analysis of Genetic Susceptibility and Physiological Risk Factors [PDF]
Anfal Mohammed Khudhair +8 more
openalex +1 more source
2016 Carl W. Gottschalk Distinguished Lectureship of the American Physiological Society Renal Section [PDF]
openalex +1 more source
Microbiota‐derived quinolinic acid is used as an alternative source of replenishing the intracellular NAD+ pool induced by SIRT3 deficiency to regulate intestinal epithelial cell and T cell function, which has implications for targeting intestinal epithelial cells as an approach to the treatment of immune‐associated diseases, including colorectal ...
Ruiying Niu +12 more
wiley +1 more source
Physiologically‐based pharmacokinetic modelling guided dose evaluations of nirmatrelvir/ritonavir in renal impairment for the management of COVID‐19 [PDF]
Tat Ming Ng +2 more
openalex +1 more source
FPD‐GELNs co‐deliver Su and bioactive components. This active‐passive dual‐targeting strategy suppresses the progression of RCC through the following mechanisms: 1) inhibition of the PI3K‐Akt signaling pathway; 2) downregulation of ABCB1/P‐gp to enhance the chemosensitivity of RCC to Su; and 3) reprogramming of macrophages toward M1 polarization and ...
Haoyu Xu +8 more
wiley +1 more source
CIRCADIAN CONTROL OF RENAL FUNCTION: ADVANCES AND PERSPECTIVES IN KIDNEY PHYSIOLOGY -A REVIEW
Dr. Ghulam Nabi Pathan,Dr. Mumtaz Memon,Dr. Madiha Niamat,Dr. Soobia Pathan,Shagufta Andleeb,Dua Khowaja,Parwan Ali Ujjan
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PBRM1 ranks as the second most commonly mutated gene in ccRCC. This study reveals that PBRM1 loss promotes an immunosuppressive microenvironment by elevating M2 TAMs via the KDM5C–IL‐6 axis. These M2 TAMs, along with CAFs, form a barrier that excludes CD8+ T cells. Targeting IL‐6 synergizes with anti‐PD1 therapy, offering a promising strategy for PBRM1‐
Wenjiao Xia +14 more
wiley +1 more source

