Results 21 to 30 of about 316,846 (352)

Angiotensin II‐induced renal angiotensinogen formation is enhanced in mice lacking tumor necrosis factor‐alpha type 1 receptor

open access: yesPhysiological Reports, 2021
In hypertension induced by angiotensin II (AngII) administration with high salt (HS) intake, intrarenal angiotensinogen (AGT) and tumor necrosis factor‐alpha (TNF‐α) levels increase.
Dewan S. A. Majid   +4 more
doaj   +1 more source

Hypertension in the elderly. Which are the blood pressure threshold values? [PDF]

open access: yes, 2019
Managing blood pressure is often difficult in the elderly, not only because of comorbidities, but also due to vascular remodelling and the changes in the renal and endocrine physiology.
Battistoni, Allegra   +3 more
core   +1 more source

Enhancer and super-enhancer dynamics in repair after ischemic acute kidney injury

open access: yesNature Communications, 2020
Acute kidney injury is a major health problem amongst hospitalized patients. Here the authors provide a comprehensive characterization of enhancer and super-enhancer elements, and the transcription factor motifs associated with these elements in response
Julia Wilflingseder   +9 more
doaj   +1 more source

Signaling pathways involved in renal oxidative injury: role of the vasoactive peptides and the renal dopaminergic system [PDF]

open access: yes, 2014
The physiological hydroelectrolytic balance and the redox steady state in the kidney are accomplished by an intricate interaction between signals from extrarenal and intrarenal sources and between antinatriuretic and natriuretic factors.
Choi, Marcelo Roberto   +6 more
core   +3 more sources

From Proteinuria to Fibrosis: An Update on Pathophysiology and Treatment Options

open access: yesKidney & Blood Pressure Research, 2021
Background: Proteinuria is a key biomarker in nephrology. It is central to diagnosis and risk assessment and the primary target of many important therapies.
Sonia Sharma, Brendan Smyth
doaj   +1 more source

Renal Physiology in Pregnancy [PDF]

open access: yesObstetrical & Gynecological Survey, 1979
Summary The changes which occur in renal excretory function during pregnancy are discussed. The relationship between glomerular filtration rate and effective renal plasma flow is examined in the light of new serial data obtained under conditions of saline diuresis.
openaire   +3 more sources

Angiotensin II-induced podocyte apoptosis is mediated by endoplasmic reticulum stress/PKC-δ/p38 MAPK pathway activation and trough increased Na+/H+ exchanger isoform 1 activity

open access: yesBMC Nephrology, 2018
Background Angiotensin II (Ang II) contributes to the progression of renal diseases associated with proteinuria and glomerulosclerosis mainly by inducing podocyte apoptosis.
Vanessa Gerolde Cardoso   +8 more
doaj   +1 more source

Intravital Imaging with Two-Photon Microscopy: A Look into the Kidney

open access: yesPhotonics, 2022
Fluorescence microscopy has represented a crucial technique to explore the cellular and molecular mechanisms in the field of biomedicine. However, the conventional one-photon microscopy exhibits many limitations when living samples are imaged.
Vincenzo Costanzo, Michele Costanzo
doaj   +1 more source

Versatility of NaCl transport mechanisms in the cortical collecting duct [PDF]

open access: yes, 2017
Versatility of NaCl transport mechanisms in the cortical collecting duct. Am J Physiol Renal Physiol 313: F1254 –F1263, 2017. First published September 6, 2017; doi:10.1152/ajprenal.00369.2017.—The cortical collecting duct (CCD) forms part of the ...
Crambert, Gilles, Edwards, Aurelie
core   +1 more source

High‐salt intake reduces renal tissue levels of inflammatory cytokines in mice

open access: yesPhysiological Reports, 2021
High salt (HS) intake is usually considered as an aggravating factor to induce inflammatory renal injury. However, the changes in the renal levels of inflammatory cytokines during HS intake is not yet clearly defined.
Purnima Singh   +3 more
doaj   +1 more source

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