Results 31 to 40 of about 3,116,502 (374)

Glucose-induced down regulation of thiamine transporters in the kidney proximal tubular epithelium produces thiamine insufficiency in diabetes [PDF]

, 2012
Increased renal clearance of thiamine (vitamin B1) occurs in experimental and clinical diabetes producing thiamine insufficiency mediated by impaired tubular re-uptake and linked to the development of diabetic nephropathy.
A Adaikalakoteswari, A AntonySunil, A Makino, A Turano, Anindita Das, AO Phillips, B Ashokkumar, B Dutta, B Sihag, BR Chamberlain, CME Tallaksen, Daniel Zehnder, ED Schleicher, Fang Zhang, G Gastaldi, GLJ Page, Guerman Molostvov, H Lum, H Smithline, HM Said, I Hubatsch, J Rieck, James R. Larkin, JC Reidling, JC Reidling, JC Reidling, JD Eudy, KA Robinson, Lisa Godfrey, MJ Boulware, MJ Ryan, MW Pfaffl, N Rabbani, N Rabbani, N Takahashi, N Tasevska, Naila Rabbani, Paul J. Thornalley, PJ Thornalley, R Babaei-Jadidi, S Sander, SM Nabokina, VS Subramanian   +42 more
core   +12 more sources

Maternal fructose intake during pregnancy and lactation: Later effects on renal function

Physiological Reports, 2022
Excessive fructose consumption has been associated with hypertension and metabolic disorders and can alter physiological adaptations during pregnancy, with long‐term detrimental consequences.
Leticia M. Monteiro, Celine F. Barbosa, Debora C. K. Lichtenecker, Rogério Argeri, Guiomar N. Gomes   +4 more
doaj   +1 more source

Physiology of the Renal Interstitium [PDF]

Clinical Journal of the American Society of Nephrology, 2015
Long overlooked as the virtual compartment and then strictly characterized through descriptive morphologic analysis, the renal interstitium has finally been associated with function. With identification of interstitial renin- and erythropoietin-producing cells, the most prominent endocrine functions of the kidney have now been attributed to the renal ...
Zeisberg, Michael, Kalluri, Raghu
openaire   +4 more sources

Acclimation to a High‐Salt Diet Is Sex Dependent

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Premenopausal women are less likely to develop hypertension and salt‐related complications than are men, yet the impact of sex on mechanisms regulating Na+ homeostasis during dietary salt challenges is poorly defined.
Eman Y. Gohar, Carmen De Miguel, Ijeoma E. Obi, Elizabeth M. Daugherty, Kelly A. Hyndman, Bryan K. Becker, Chunhua Jin, Randee Sedaka, Jermaine G. Johnston, Pengyuan Liu, Joshua S. Speed, Tanecia Mitchell, Alison J. Kriegel, Jennifer S. Pollock, David M. Pollock   +14 more
doaj   +1 more source

Nonselective and A2a-Selective Inhibition of Adenosine Receptors Modulates Renal Perfusion and Excretion Depending on the Duration of Streptozotocin-Induced Diabetes in Rats

Pharmaceuticals, 2023
Long-lasting hyperglycaemia may alter the role of adenosine-dependent receptors (P1R) in the control of kidney function. We investigated how P1R activity affects renal circulation and excretion in diabetic (DM) and normoglycaemic (NG) rats; the receptors’
Joanna Dorota Sitek, Marta Kuczeriszka, Agnieszka Walkowska, Elżbieta Kompanowska-Jezierska, Leszek Dobrowolski   +4 more
doaj   +1 more source

Sphingosine 1-phosphate in renal diseases [PDF]

, 2013
Because of its highly bioactive properties sphingosine 1-phosphate (S1P) is an attractive target for the treatment of several diseases. Since the expression of sphingosine kinases as well as S1P receptors was demonstrated in the kidney, questions about ...
Huwiler, Andrea, Koch, Alexander, Pfeilschifter, Josef Martin   +2 more
core   +5 more sources

Early life stress induces dysregulation of the heme pathway in adult mice

Physiological Reports, 2021
Early life stress (ELS) is associated with cardiovascular disease (CVD) risk in adulthood, but the underlying vascular mechanisms are poorly understood.
Yasminye D. Pettway, Thomas H. Neder, Dao H. Ho, Brandon M. Fox, Mariah Burch, Jackson Colson, Xiaofen Liu, Cailin E. Kellum, Kelly A. Hyndman, Jennifer S. Pollock   +9 more
doaj   +1 more source

Angiotensin II‐induced renal angiotensinogen formation is enhanced in mice lacking tumor necrosis factor‐alpha type 1 receptor

Physiological Reports, 2021
In hypertension induced by angiotensin II (AngII) administration with high salt (HS) intake, intrarenal angiotensinogen (AGT) and tumor necrosis factor‐alpha (TNF‐α) levels increase.
Dewan S. A. Majid, Eamonn Mahaffey, Alexander Castillo, Minolfa C. Prieto, L. Gabriel Navar   +4 more
doaj   +1 more source

Function of Renal Nerves in Kidney Physiology and Pathophysiology.

Annual Review of Physiology, 2021
Renal sympathetic (efferent) nerves play an important role in the regulation of renal function, including glomerular filtration, sodium reabsorption, and renin release.
J. Osborn, Roman Tyshynsky, L. Vulchanova   +2 more
semanticscholar   +1 more source

Effect of Calcitriol on the Renal Microvasculature Differentiation Disturbances Induced by AT1 Blockade During Nephrogenesis in Rats

Frontiers in Medicine, 2020
Alterations in the renal vasculature during fetal programming can cause disturbances in renal structure and function that persist into adulthood. Calcitriol can affect cellular differentiation and proliferation, and promote endothelial cell maintenance ...
Amanda L. Deluque, Lucas F. de Almeida, Heloísa D. C. Francescato, Cleonice G. A. da Silva, Roberto S. Costa, José Antunes-Rodrigues, Terezila M. Coimbra   +6 more
doaj   +1 more source