Emerging key roles for P2X receptors in the kidney [PDF]
, 2013 P2X ionotropic non-selective cation channels are expressed throughout the kidney and are activated in a paracrine or autocrine manner following the binding of extracellular ATP and related extracellular nucleotides. Whilst there is a wealth of literature
Birch, R. E. +3 more
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Sympathetic nerve-derived ATP regulates renal medullary vasa recta diameter via pericyte cells: a role for regulating medullary blood flow? [PDF]
, 2013 Pericyte cells are now known to be a novel locus of blood flow control, being able to regulate capillary diameter via their unique morphology and expression of contractile proteins.
Crawford, C. +4 more
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Biological Pathways and Potential Targets for Prevention and Therapy of Chronic Allograft Nephropathy [PDF]
, 2014 Renal transplantation (RT) is the best option for patients with end-stage renal disease, but the half-life is limited to a decade due to progressive deterioration of renal function and transplant failure from chronic allograft nephropathy (CAN), which is
Haylor, John, Shrestha, Badri Man
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BMC Nephrology, 2018 Background Angiotensin II (Ang II) contributes to the progression of renal diseases associated with proteinuria and glomerulosclerosis mainly by inducing podocyte apoptosis.
Vanessa Gerolde Cardoso +8 more
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Hypertension in the elderly. Which are the blood pressure threshold values? [PDF]
, 2019 Managing blood pressure is often difficult in the elderly, not only because of comorbidities, but also due to vascular remodelling and the changes in the renal and endocrine physiology.
Battistoni, Allegra +3 more
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Enhancer and super-enhancer dynamics in repair after ischemic acute kidney injury
Nature Communications, 2020 Acute kidney injury is a major health problem amongst hospitalized patients. Here the authors provide a comprehensive characterization of enhancer and super-enhancer elements, and the transcription factor motifs associated with these elements in response
Julia Wilflingseder +9 more
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Renal Physiology in Pregnancy [PDF]
Obstetrical & Gynecological Survey, 1979 Summary The changes which occur in renal excretory function during pregnancy are discussed. The relationship between glomerular filtration rate and effective renal plasma flow is examined in the light of new serial data obtained under conditions of saline diuresis.
openaire +2 more sources
The carotid body as a therapeutic target for the treatment of sympathetically mediated diseases [PDF]
, 2013 [no ...
Abdala, Ana P +13 more
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High‐salt intake reduces renal tissue levels of inflammatory cytokines in mice
Physiological Reports, 2021 High salt (HS) intake is usually considered as an aggravating factor to induce inflammatory renal injury. However, the changes in the renal levels of inflammatory cytokines during HS intake is not yet clearly defined.
Purnima Singh +3 more
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Intravital Imaging with Two-Photon Microscopy: A Look into the Kidney
Photonics, 2022 Fluorescence microscopy has represented a crucial technique to explore the cellular and molecular mechanisms in the field of biomedicine. However, the conventional one-photon microscopy exhibits many limitations when living samples are imaged.
Vincenzo Costanzo, Michele Costanzo
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