Results 51 to 60 of about 3,116,502 (374)

Emerging key roles for P2X receptors in the kidney [PDF]

, 2013
P2X ionotropic non-selective cation channels are expressed throughout the kidney and are activated in a paracrine or autocrine manner following the binding of extracellular ATP and related extracellular nucleotides. Whilst there is a wealth of literature
Birch, R. E., Peppiatt-Wildman, Claire M., Schwiebert, E. M., Wildman, Scott S.P.   +3 more
core   +2 more sources

Alterations of haemodynamic parameters in spontaneously hypertensive rats by Aristolochia ringens Vahl. (Aristolochiaceae)

Journal of Traditional and Complementary Medicine, 2018
Aristolochia ringens Vahl. (Aristolochiaceae (AR); 馬兜鈴 mǎ dōu líng) is used traditionally in Nigeria for the management of various disorders including oedema. Preliminary investigation revealed its modulatory effect on the cardiovascular system.
Flora Ruth Aigbe, Abdul Sattar Zubaid Munavvar, Hassan Rathore, Olorunfemi Eseyin, Yen Pei Pei, Safia Akhtar, Ashfaq Chohan, Hui Jin, Jooli Khoo, Samual Tan, Mohammed Lazhari, Sheryar Afzar, Fiaz Ahmed, Olufunmilayo Olaide Adeyemi, Edward Johns   +14 more
doaj   +1 more source

The relationship between P2X4 and P2X7: a physiologically important interaction? [PDF]

, 2013
Purinergic signaling within the kidney is becoming an important focus in the study of renal health and disease. The effectors of ATP signaling, the P2Y and P2X receptors, are expressed to varying extents in and along the nephron.
Birch, Rebecca E, Craigie, Eilidh, Unwin, Robert J, Wildman, Scott S.P.   +3 more
core   +3 more sources

Multiparametric assessment of renal physiology in healthy volunteers using noninvasive magnetic resonance imaging.

AJP - Renal Physiology, 2019
Noninvasive methods of magnetic resonance imaging (MRI) can quantify parameters of kidney function. The main purpose of this study was to determine baseline values of such parameters in healthy volunteers.
Per Eckerbom, P. Hansell, E. Cox, Charlotte E Buchanan, J. Weis, F. Palm, S. Francis, P. Liss   +7 more
semanticscholar   +1 more source

A large drawing of a nephron for teaching medical students renal physiology, histology, and pharmacology.

Advances in Physiology Education, 2018
The purpose of this study is to see whether a large drawing of a nephron helped medical students in self-directed learning groups learn renal physiology, histology, and pharmacology before discussing clinical cases.
Philip G Robinson, David Newman, Cara L Reitz, Lena Z Vaynberg, Dalbir Bahga, Morton H Levitt   +5 more
semanticscholar   +1 more source

Versatility of NaCl transport mechanisms in the cortical collecting duct [PDF]

, 2017
Versatility of NaCl transport mechanisms in the cortical collecting duct. Am J Physiol Renal Physiol 313: F1254 –F1263, 2017. First published September 6, 2017; doi:10.1152/ajprenal.00369.2017.—The cortical collecting duct (CCD) forms part of the ...
Crambert, Gilles, Edwards, Aurelie
core   +1 more source

Chymase Dependent Pathway of Angiotensin II Generation and Rapeseed Derived Peptides for Antihypertensive Treatment of Spontaneously Hypertensive Rats

Frontiers in Pharmacology, 2021
The contribution of chymase, one of the enzymes responsible for angiotensin II generation in non-ACE pathway, remains unclear in the development of hypertension.
Iwona Baranowska, Olga Gawrys, Malwina M. Roszkowska-Chojecka, Bozena Badzynska, Dagmara Tymecka, Krzysztof H. Olszynski, Elzbieta Kompanowska-Jezierska   +6 more
doaj   +1 more source

Purinergic receptor mediated calcium signalling in urothelial cells [PDF]

, 2019
Non-neuronal ATP released from the urothelium in response to bladder stretch is a key modulator of bladder mechanosensation. Whilst non-neuronal ATP acts on the underlying bladder afferent nerves to facilitate sensation, there is also the potential for ...
Brierley, Stuart M, Chess-Williams, Russell, Grundy, David, Grundy, Luke, Sellers, Donna J   +4 more
core   +3 more sources

HDAC9 is an epigenetic repressor of kidney angiotensinogen establishing a sex difference

Biology of Sex Differences, 2017
Background Sexual difference has been shown in the pathogenesis of chronic kidney disease induced by hypertension. Females are protected from hypertension and related end-organ damage.
Camille T. Bourgeois, Ryousuke Satou, Minolfa C. Prieto   +2 more
doaj   +1 more source

Paricalcitol prevents MAPK pathway activation and inflammation in adriamycin-induced kidney injury in rats [PDF]

Journal of Pathology and Translational Medicine
Background Activation of the mitogen-activated protein kinase (MAPK) pathway induces uncontrolled cell proliferation in response to inflammatory stimuli.
Amanda Lima Deluque, Lucas Ferreira de Almeida, Beatriz Magalhães Oliveira, Cláudia Silva Souza, Ana Lívia Dias Maciel, Heloísa Della Coletta Francescato, Cleonice Giovanini, Roberto Silva Costa, Terezila Machado Coimbra   +8 more
doaj   +1 more source