Results 161 to 170 of about 171,022 (301)

Construction of PANoptosis‐Inhibiting Carbonized Polymer Dots via Machine Learning Potential for Mitigating Chemodrug‐Induced Nephrotoxicity

Advanced Science, EarlyView.
An enhanced sampling method is developed for molecular dynamics based on trained machine learning force fields to guide the construction of PANoptosis‐inhibiting carbonized polymer dots (Lu‐CDs) derived from a flavonoid compound for treating chemodrug‐induced nephrotoxicity.
Xinchen Liu, Jiaxin Zhang, Xiangyu Yan, Nuo Li, Yu‐Chao Dong, Zihao Wang, Daowei Li, Yong Du, Huan Wang   +8 more
wiley   +1 more source

Renal Replacement Therapy in Lupus Nephritis-Related End-Stage Kidney Disease: A Systematic Review and Meta-Analysis. [PDF]

ACR Open Rheumatol
Kawtharany H, Jorge A, Azzam M, Bartels CM, Cunha JS, DeQuattro K, Fava A, Figueroa-Parra G, Garg S, Greco J, Cuéllar-Gutiérrez MC, Iyer P, Johannemann AS, Kasturi S, Khawandi J, Kirou KA, Legge A, Liang KV, Lockwood MM, Sanchez-Rodriguez A, Turgunbaev M, Williams JN, Sammaritano LR, Askanase A, Bermas BL, Dall'Era M, Duarte-García A, Hiraki LT, Rovin B, Son MBF, Turner AS, Mustafa RA.   +31 more
europepmc   +1 more source

Renal replacement therapies [PDF]

, 2005
openaire   +1 more source

Activating the Osteoblastic USP26 Pathway Alleviates Multi‐Organ Fibrosis by Decreasing Insulin Resistance

Advanced Science, EarlyView.
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang, Wenkai Ye, Liang He, Zhou Dan, Leilei Chang, Zijie You, Yuanyue Jiang, Guoqing Tang, Lianfu Deng, Changwei Li   +9 more
wiley   +1 more source

Combination of extracorporeal membrane oxygenation and continuous renal replacement therapy: a systematic review of the past decade (2014-2023). [PDF]

BMC Anesthesiol
Liu L, Zhao X, Jiang J, Gao J, Niu B, Zhang L, Wang G.   +6 more
europepmc   +1 more source

Failing kidneys: renal replacement therapies in the ICU [PDF]

Purvi P. Patel, Tanya Egodage
openalex   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

Development and validation of an interpretable predictive machine learning model for successful weaning of continuous renal replacement therapy. [PDF]

Sci Rep
Popoff B, Delange B, Nicolas J, Le Gall A, Dahamna B, Cuggia M, Clavier T, Bouzillé G.   +7 more
europepmc   +1 more source

NAD+‐Dependent Enzyme SIRT3 Limits Intestinal Epithelial Cell Functions Through NAD+ Synthesis Pathway in Colorectal Cancer

Advanced Science, EarlyView.
Microbiota‐derived quinolinic acid is used as an alternative source of replenishing the intracellular NAD+ pool induced by SIRT3 deficiency to regulate intestinal epithelial cell and T cell function, which has implications for targeting intestinal epithelial cells as an approach to the treatment of immune‐associated diseases, including colorectal ...
Ruiying Niu, Yingjie Dong, Jianghui Tong, Jingxuan Xia, Longhao Zhao, Zi Geng, Yingxin Lin, Jinghe Zhang, Xinyi Liu, Manqi Fang, Xi Jin, Yujing Bi, Guangwei Liu   +12 more
wiley   +1 more source

Continuous Renal Replacement Therapy in Children. [PDF]

Indian Pediatr
Haddad M, Butani L.
europepmc   +1 more source