Results 161 to 170 of about 618,690 (430)

Exploring challenges and considerations while providing hemodialysis to pediatric, elderly, and pregnant cases: A narrative review of globally published literature

Clinical Epidemiology and Global Health
Background: Hemodialysis patients have unique physiological characteristics that necessitate specialized care during the treatment. As the prevalence of kidney disease continues to rise, the importance of addressing the unique needs of these patient ...
Megha Nagaraj Nayak, Veena Natti Krishna
doaj  

Multipotentials of new asymmetric cellulose triacetate membrane for on-line hemodiafiltration both in postdilution and predilution

Renal Replacement Therapy, 2019
Background On-line hemodiafiltration (OL-HDF) has been generally provided mainly by the postdilution method in Europe and the rest of the world; however, in Japan, it has been provided mostly by the predilution method in order to ameliorate dialysis ...
Yusaku Tanaka, Hiroyuki Michiwaki, Hirofumi Asa, Daisuke Hirose, Tomohiro Tao, Jun Minakuchi   +5 more
doaj   +1 more source

Ultrasound tongue imaging for diarization and alignment of child speech therapy sessions [PDF]

arXiv, 2019
We investigate the automatic processing of child speech therapy sessions using ultrasound visual biofeedback, with a specific focus on complementing acoustic features with ultrasound images of the tongue for the tasks of speaker diarization and time-alignment of target words.
arxiv  

PCSK9 Promotes the Malignancy of Triple‐negative Breast Cancer Cells by Reducing Cholesterol Levels at the Plasma Membrane to Activate EGFR and HER3

Advanced Science, EarlyView.
By decreasing cholesterol and lipid raft levels in the plasma membrane, proprotein convertase subtilisin/kexin type 9 (PCSK9) boosts human epidermal growth factor receptor 1 and 3 (EGFR and HER3) activation, driving tumor growth and metastasis in triple‐negative breast cancer (TNBC).
Tianhong Li, Renfei Wu, Kathy Qian Luo
wiley   +1 more source

Microbiota‐Derived Inosine Suppresses Systemic Autoimmunity via Restriction of B Cell Differentiation and Migration

Advanced Science, EarlyView.
Lactobacillus johnsonii and its associated purine metabolite inosine not only restrict systemic B cell differentiation, but also contribute to immune cell infiltration in the kidneys, thereby serving dual functions in mitigating the progression of systemic lupus erythematosus (SLE).
Lingyu Gao, Yuhan Zhang, Zhi Hu, Shengwen Chen, Qiaolin Wang, Yong Zeng, Huiqi Yin, Junpeng Zhao, Yijing Zhan, Changxing Gao, Yue Xin, Bing Chen, Stijn van der Veen, Ming Zhao, Deyu Fang, Qianjin Lu   +15 more
wiley   +1 more source

Does continuous renal replacement therapy favourably influence the outcome of the patients? [PDF]

, 2017
Continuous haemodialysis and continuous haemofiltration are efficient and safe techniques for the treatment of acute renal failure. Theoretical advantages are improved haemodynamic stability and easier fluid removal.
Frey, F. J., Jakob, S. M., Uehlinger, D. E.   +2 more
core  

HIC1 suppresses Tumor Progression and Enhances CD8+ T Cells Infiltration Through Promoting GSDMD‐induced Pyroptosis in Gastric Cancer

Advanced Science, EarlyView.
These findings elucidate the innovative role of HIC1 as a transcriptional activator in GC, driving the initiation of pyroptosis and enhancing CD8+ T cell infiltration, which has certain novelty and creative significance. Collectively, targeting HIC1 can present an appealing immunotherapeutic strategy to improve outcomes in GC patients.
Mengjie Kang, Wenqi Du, Lina Ding, Mengdi Wu, Dongsheng Pei   +4 more
wiley   +1 more source

Long-term prognosis after acute kidney injury requiring renal replacement therapy [PDF]

, 2017
Background. Data on the long-term survival and renal function of patients with acute kidney injury (AKI) treated with continuous renal replacement therapy are scarce. Methods.
Martin, Pierre-Yves, Perneger, Thomas, Pugin, Jerome, Romand, Jacques, Saudan, Patrick, Triverio, Pierre-Alain   +5 more
core  

Diagnosis, evaluation, and management of acute kidney injury : a KDIGO summary (part 1) [PDF]

, 2013
Acute kidney injury (AKI) is a common and serious problem affecting millions and causing death and disability for many. In 2012, Kidney Disease: Improving Global Outcomes completed the first ever, international, multidisciplinary, clinical practice ...
Kellum, John A, Lameire, Norbert
core   +3 more sources

Integrative Multi‐Omics and Routine Blood Analysis Using Deep Learning: Cost‐Effective Early Prediction of Chronic Disease Risks

Advanced Science, EarlyView.
Omicsformer, a deep learning model, integrates multi‐omics and routine blood data to accurately predict risks for nine chronic diseases, including cancer and cardiovascular conditions. Validated using large scale clinical data, it reveals early risk trajectories, advancing personalized medicine and offering a cost‐effective, community‐based solution ...
Zhibin Dong, Pei Li, Yi Jiang, Zhihan Wang, Shihui Fu, Hebin Che, Meng Liu, Xiaojing Zhao, Chunlei Liu, Chenghui Zhao, Qin Zhong, Chongyou Rao, Siwei Wang, Suyuan Liu, Dayu Hu, Dongjin Wang, Juntao Gao, Kai Guo, Xinwang Liu, En Zhu, Kunlun He   +20 more
wiley   +1 more source