Results 171 to 180 of about 172,502 (268)

Postangiography Prediction of Renal Replacement Therapy in Acute Myocardial Infarction-Related Cardiogenic Shock: Least Absolute Shrinkage and Selection Operator Nomogram Development and Validation. [PDF]

JMIR Cardio
Daoulah A, M Ladna J, Arabi A, Elmahrouk A, Seraj S, M Aloui H, Alshehri M, Almahmeed W, Panduranga P, Yousif N, Lotfi A, Qutub M, Alharbi W, Rajan R, Abdirahman Kahin M, Alenezi A, Al Maashani S, Hassan T, Alswuaidi J, Eltaieb F, Abdulhadi Aldossari M, Al Jarallah M, Elganady A, Alzahrani B, Alqahtani A, Omar M Al Nasser F, A Noor H, Alama MN, Aldossari A, Al Obaikan S, Ali Almarghany A, Kanbr O, Elmahrouk Y, A M Abdulhabeeb I, Balghith M, S Hersi A, Antony H, Fathey Hussien A, Almoghairi A, Alama MMA, Ajaz Ghani M, Rahbi H, Basardah A, Alshehri B, Alama A, AlObaid L, Abualnaja S, Shahzad Chachar T, Khan H, Hashmani S, A Ghonim A, Almerri K, Alsofayan R, M Tawengi A, M Shawky A, Alshehri A, Arafat A, Jamjoom A.   +57 more
europepmc   +1 more source

Targeting Lipopolysaccharide Transport Induces Membrane Lipid Remodeling and Sensitizes Acinetobacter baumannii to Colistin Treatment

Advanced Science, EarlyView.
This study identifies C4 as a lead inhibitor of the Lpt system. Notably, C4 potentiates colistin activity by disrupting LPS transport and remodeling phospholipid homeostasis, revealing a functional interplay between the Lpt and Mla systems. These findings establish a mechanistic link between Lpt inhibition and membrane lipid remodeling, positioning Lpt–
Jianya Luo, Hetianzi Zhang, Jinju Cai, Shuang Zhou, Haijie Zhang, Zhiqiang Wang, Yuan Liu   +6 more
wiley   +1 more source

Risk prediction of continuous renal replacement therapy in patients with acute kidney injury after lung transplantation. [PDF]

J Intensive Med
Ding S, Lin H, Chen J, Mai S, Zhu G, Teng G, Chen J, Huang M.   +7 more
europepmc   +1 more source

Biomimetic Hydrogel System Targeting S100A8 Centered Neuroimmune Crosstalk and Hypoxia Induced Neuronal Injury

Advanced Science, EarlyView.
A biomimetic hydrogel (HPC@Gel) was developed for traumatic brain injury repair by combining oxygen‐carrying hemoglobin nanoparticles and anti‐inflammatory carbon quantum dots within a brain‐like matrix. The system alleviated hypoxia, reduced harmful neuroimmune signaling, protected neurons, supported neural regeneration, and improved neurological and ...
Peng Liu, Xiaoyang Wu, Xiaoyin Liu, Yuyan Wang, Shichao Jiang, Kai Wu, Gaowei Li, Jie Ding, Chengheng Wu, Dan Wei, Jing Sun, Hongsong Fan, Liangxue Zhou   +12 more
wiley   +1 more source

Continuous Renal Replacement Therapy During Liver Transplant: The Anesthesiologist-Nephrologist Collaboration at a Tertiary University Hospital in Italy. [PDF]

Clin Transplant
Laici C, Ricci D, Gibertoni D, Mancini E, Zucchelli A, Siniscalchi A.   +5 more
europepmc   +1 more source

DHODH Drives Sunitinib Resistance Via a Non‐Enzymatic Mechanism by Inhibiting TRIM28 Ubiquitination and Consequent VEGFA Activation in RCC

Advanced Science, EarlyView.
This non‑enzymatic function of DHODH drives sunitinib resistance by competing with TRIM37 to block TRIM28 ubiquitination, thereby stabilizing TRIM28 and activating VEGFA transcription. Disrupting the DHODH–TRIM28 interaction with lisaftoclax restores drug sensitivity.
Shijie Qian, Shihang Pu, Zhipeng Xu, Yiheng Ding, Ling Jin, Baochao Li, Qi Li, Xiaohai Xi, Zengjun Wang, Jiajun Xing, Aiming Xu   +10 more
wiley   +1 more source

A Single-Center Review of Renal Replacement Therapy in Patients With Acute Traumatic Brain Injury. [PDF]

Cureus
Topper G, Bamimore M, Hess T, Metheny J, Morris P, Plumb J, Valeri A, Hunter K, Mossop C, Egodage T.   +9 more
europepmc   +1 more source