Results 171 to 180 of about 171,022 (301)

Effect of continuous renal replacement therapy on serum levels of inflammatory cytokines/interleukin-17 in severe acute pancreatitis

Diana Iosif, Adrian Paul Suceveanu, Marius Dragos Prazaru, I. Cîndea, V. Gherghina, Anca Pantea Stoian, Laura Mazilu, Dragoş Şerban, Alina Nicoara, Andra‐Iulia Suceveanu   +9 more
openalex   +2 more sources

Folic Acid‐Modified Ginger‐Derived Exosome‐Like Nanoparticles Co‐Delivering Sunitinib Suppress Renal Cell Carcinoma via PI3K‐Akt Pathway Inhibition, P‐gp Downregulation, and Macrophage Reprogramming

Advanced Science, EarlyView.
FPD‐GELNs co‐deliver Su and bioactive components. This active‐passive dual‐targeting strategy suppresses the progression of RCC through the following mechanisms: 1) inhibition of the PI3K‐Akt signaling pathway; 2) downregulation of ABCB1/P‐gp to enhance the chemosensitivity of RCC to Su; and 3) reprogramming of macrophages toward M1 polarization and ...
Haoyu Xu, Daixing Hu, Shixue Liu, Lei Yang, Junwu Li, Yuanyuan Bai, Guozhi Zhao, Wei Tang, Li Jiang   +8 more
wiley   +1 more source

WCN25-3107 SURVIVAL ANALYSIS OF PATIENTS WITH PRIMARY RENAL AMYLOIDOSIS

Kidney International Reports
Kirill Komissarov, Marina Guberskaya, Aliaksei Narbin, Maryia Ustsinovich, Veronika Pinchuk, Iryna Lendzina, Victoriya Smolnikova, Alena Kuzmich, Igor Iskrov, Aleh Kalachyk   +9 more
doaj   +1 more source

Jugular vein or femoral vein? A comparison of vascular routes based on effectiveness and hemodynamic effects of continuous renal replacement therapy. [PDF]

Medicine (Baltimore)
Firat A, Akbulut M, Özdemir Ö, Toptaş Firat B.   +3 more
europepmc   +1 more source

Plasma inflammatory and apoptosis markers are associated with dialysis dependence and death among critically ill patients receiving renal replacement therapy [PDF]

, 2014
Raghavan Murugan, Xiao‐Yan Wen, Nilesh Shah, MinJae Lee, Lan Kong, Francis Pike, Christopher Keener, Mark L. Unruh, Kevin W. Finkel, Anitha Vijayan, Paul M. Palevsky, Yen‐Hsuan Ni, Melinda Carter, Michele Elder, John A. Kellum   +14 more
openalex   +1 more source

Dipiperazine‐Phenyl Derivatives Based on Convergent Molecular Platforms Can Reverse Multidrug Resistance in Gram‐Negative Bacteria by Inhibiting Efflux and Permeabilizing Cell Membranes

Advanced Science, EarlyView.
By integrating a convergent molecular platform strategy, this study designed a novel dual‐target C5 to combat multidrug‐resistant Gram‐negative bacteria. C5 synergistically enhances antibiotic efficacy by inhibiting efflux pumps and increasing bacterial membrane permeability.
Jiale Dong, Ting Guo, Yi Huang, Yangchun Ma, Weijin Chen, Jie Xue, Jun Jiang, Enhui Dong, Yue Kong, Hang Ding, Wenlong Zhang, Shutao Ma   +11 more
wiley   +1 more source

The role of continuous renal replacement therapy in critically ill children with cancer and multiple organ dysfunction syndrome. [PDF]

J Pediatr (Rio J)
Veiga FPLF, Araujo OR, Araujo AS, Bicalho MS, Andrade MC, Silva DCB.   +5 more
europepmc   +1 more source

Development and Validation of a nomogram for Predicting Catheter Dysfunction in Patients Receiving Continuous Renal Replacement Therapy in Intensive Care Units: an observational Cohort Study [PDF]

Jie-Ru Yang, Mo-Qi Li, Ying Yin, Yu Zou, Wei Guo, Wei Wang, Jiachuan Xiong, Yu Lu, Wenchang He, Quanchao Zhang   +9 more
openalex   +1 more source

Ultrasound‐Boosted Liposomal Prodrug Overcomes Age‐Associated Biodistribution Disparity in Pediatric Solid Tumor Therapy

Advanced Science, EarlyView.
The age‐associated disparity of nanocarrier biodistribution limits the nanotherapeutics of childhood solid tumors. This study developed an ultrasound‐activated liposomal prodrug (CSCPTL) to overcome the age‐associated disparity of off‐target distribution.
Danfei Chen, Junjun Xu, Jian Chen, Jue Hu, Xiaobo Xuan, Haifang Cai, Mingdong Yang, Zhuxian Zhou, Guowei Wang   +8 more
wiley   +1 more source

HSP70 Interactome‐Mediated Proteolysis Targeting Chimera (HSP70‐PROTAC) for Ferroptosis‐Driven Cancer Treatment

Advanced Science, EarlyView.
This study reports a novel targeted protein degradation strategy termed “HSP70‐PROTAC” that recruits Hsc70 complex to a target protein for inducing degradation. Among them, GDAz‐3 exhibits effective GPX4 degradation activity via UPS/CMA processes, triggering ferroptosis‐driven anticancer activity in vitro and in vivo.
Jinyun Dong, Yulong Li, Hui Liang, Zumei Wu, Shiqun Wang, Yichao Wang, Jieyu Xu, Yanning Lan, Maohua Cai, Guangzhao Pan, Haiyan Yang, Kai Miao, Zhe‐Sheng Chen, Fangfang Tao, Xuelei Ma, Jiang‐Jiang Qin   +15 more
wiley   +1 more source