Results 171 to 180 of about 618,690 (430)

Renal Replacement Therapy for Patients with Acute Liver Failure Awaiting Orthotopic Hepatic Transplantation [PDF]

, 1991
Andrew Davenport
openalex   +1 more source

Perspectives in renal replacement therapy: Haemodialysis

Nephrology, 2018
Haemodialysis (HD) was the first procedure that had demonstrated the ability to partially replace renal function, and became the most widely utilized treatment for patients with end‐stage renal disease (ESRD).
A. Liew
semanticscholar   +1 more source

Targeting Senescence with Apigenin Improves Chemotherapeutic Efficacy and Ameliorates Age‐Related Conditions in Mice

Advanced Science, EarlyView.
As a plant‐derived flavonoid, apigenin directly targets PRDX6 to inhibit its PLA2 activity, blocking HSPA8 activation and disturbing its interactions with ATM and p38MAPK in senescent cells. By dampening wide spectrum expression of the SASP, apigenin prevents loss of tissue homeostasis, improves organ function, and alleviates multiple age‐related ...
Hongwei Zhang, Qixia Xu, Zhirui Jiang, Rong Sun, Qun Wang, Sanhong Liu, Xin Luan, Judith Campisi, James L. Kirkland, Weidong Zhang, Yu Sun   +10 more
wiley   +1 more source

Evolution of Nephrology and Renal Replacement Therapy [PDF]

, 1993
V. Bonomini
openalex   +1 more source

Icaritin Represses Autophagy to Promote Colorectal Cancer Cell Apoptosis and Sensitized Low‐Temperature Photothermal Therapy via Targeting HSP90‐TXNDC9 Interactions

Advanced Science, EarlyView.
Icaritin demonstrates broad antitumor effects by inhibiting colorectal cancer (CRC) cell proliferation, migration, invasion, and causing cell cycle arrest. It induces apoptosis by repressing autophagic flux through disrupting HSP90‐TXNDC9 interactions.
Dan He, Siliang Chen, Xiaoyun Wang, Xiang Wen, Changyang Gong, Lei Liu, Gu He   +6 more
wiley   +1 more source

Profiling mortality patterns and place of death in patients on maintenance hemodialysis: a retrospective study in a tertiary care academic hospital in India

BMC Palliative Care
Background End-stage kidney disease (ESKD) significantly burdens healthcare systems and increases mortality. In India, approximately 175,000 individuals are relying on maintenance hemodialysis (mHD).
Surya Gayathri M, Bharathi Naik, Arun Ghoshal, Anuja Damani, Shankar Prasad Nagaraju   +4 more
doaj   +1 more source

Synchronising audio and ultrasound by learning cross-modal embeddings [PDF]

arXiv, 2019
Audiovisual synchronisation is the task of determining the time offset between speech audio and a video recording of the articulators. In child speech therapy, audio and ultrasound videos of the tongue are captured using instruments which rely on hardware to synchronise the two modalities at recording time. Hardware synchronisation can fail in practice,
arxiv  

Non-renal indications for continuous renal replacement therapy [PDF]

, 1999
Miet Schetz
openalex   +1 more source

Intensity of continuous renal replacement therapy for acute kidney injury.

Cochrane Database of Systematic Reviews, 2016
BACKGROUND Acute kidney injury (AKI) is a common condition among patients in intensive care units (ICU), and is associated with substantial morbidity and mortality.
Alicia I Fayad, D. Buamscha, A. Ciapponi
semanticscholar   +1 more source

Lactylation‐Driven NUPR1 Promotes Immunosuppression of Tumor‐Infiltrating Macrophages in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Cai et al. report that tumor‐derived lactate induces NUPR1 expression via H3K18 lactylation, which can promote the pro‐tumor M2 macrophage polarization through ERK and JNK signaling pathways. Treatment with NUPR1 selective inhibitor sensitizes synergizes with anti‐PD‐1 therapy in murine preclinical models.
Jialiang Cai, Peiling Zhang, Yufan Cai, Guiqi Zhu, Shiping Chen, Lina Song, Junxian Du, Biao Wang, Weixing Dai, Jian Zhou, Jia Fan, Yiyi Yu, Zhi Dai   +12 more
wiley   +1 more source