Results 251 to 260 of about 486,423 (351)

WCN25-1550 FACTORS ASSOCIATED WITH HEMOFILTER CLOTTING IN PATIENTS WITH ACUTE KIDNEY INJURY REQUIRING NON-ANTICOAGULANT CONTINUOUS RENAL REPLACEMENT THERAPY [PDF]

Kornchanok Vareesangthip, Thawee Chanchairujira, Thummaporn Naorungroj, Anuyoot Tuntipumiamorn, Salinthip Tiaochoktrakul   +4 more
openalex   +1 more source

A Simplified Three‐Tailed N‐Alkyl Phosphoramidate Lipid Platform Enables Inguinal Adipose‐Accumulated mRNA Delivery for Anti‐Obesity Therapy

Advanced Science, EarlyView.
This study develops an mRNA therapy encoding a long‐acting GLP‐1/FGF21 fusion protein. A three‐tailed ionizable lipid engineered three‐component lipid nanoparticle delivers the mRNA to inguinal adipose tissue. In obese mice, this targeted, dual‐hormone treatment potently reduces body weight, fat mass, presenting a localized strategy for metabolic ...
Bin Ma, Yunxuan Liu, Huijuan Zhang, Yian Fang, Yizhe Xue, Junsheng Xue, Ziqiong Jiang, Tianyan Zhou, Yanyun Hao, Fei Xie, Lei Miao   +10 more
wiley   +1 more source

β-Lactam/β-Lactamase Inhibitor Combinations in Sepsis-Associated Acute Kidney Injury and Renal Replacement Therapy. [PDF]

Antibiotics (Basel)
Lacquaniti A, Pistolesi V, Smeriglio A, Santoro D, Iannetti C, Lentini G, Chimenz R, Chirico V, Trombetta D, Morabito S, Monardo P.   +10 more
europepmc   +1 more source

Renal clearance of heparin-binding protein and elimination during renal replacement therapy: Studies in ICU patients and healthy volunteers

, 2019
Line Samuelsson, Jonas Tydén, Heiko Herwald, Magnus Hultin, Jakob Walldén, Ingrid Steinvall, Folke Sjöberg, Joakim Johansson   +7 more
openalex   +2 more sources

Biomimetic Nanomedicine for Senescence‐Modulated Immune Activation Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A multifunctional mPDZM nanoplatform is developed in this study. mPDZM integrates chemotherapy‐induced senescence, selective senolysis, and STING‐mediated immune activation. mPDZM effectively clears senescent tumor cells, remodels the tumor immune microenvironment, and enhances antitumor T‐cell responses.
Shiji Fang, Liyun Zheng, Bin Lin, Jiale Chen, Dehai Hou, Yiming Ding, Mengzhu Han, Pan Qin, Mengyuan Wang, Xiaoju Guo, Yeyu Zhang, Gaofeng Shu, Fazong Wu, Jianfei Tu, Minjiang Chen, Zhongwei Zhao, Zhuang Liu, Jiansong Ji   +17 more
wiley   +1 more source

The Urea-Creatinine Ratio as Marker of Catabolism Is Affected by Continuous Renal Replacement Therapy. [PDF]

Diagnostics (Basel)
Markl-Le Levé A, Hillinger P, Woyke S, Ronzani M, Schmid S, Kreutziger J, Rugg C.   +6 more
europepmc   +1 more source

Gram‐Scale Synthesis of Hafnium‐Rich Carbon Dots for Preclinical Computed Tomography Imaging Across Various Systems

Advanced Science, EarlyView.
Hafnium (Hf)‐rich carbon dots (Hf‐rCDs) with high metal content (40.7%) and robust batch production capacity (>2 g per batch) are synthesized via a facile air‐assisted pyrolysis method. In vivo CT imaging demonstrates outstanding performance of Hf‐rCDs across multiple physiological systems and enables high‐resolution visualization of swine cervical ...
Shuo Li, Hengrui Wu, Jianqi Deng, Qiyu Sun, Yuping Zhang, Cai Zhang, Jinbin Pan, Dingbin Liu, Xuejun Zhang, Quan Zou, Xiaoyuan Chen, Shao‐Kai Sun   +11 more
wiley   +1 more source

Development and validation of a predictive model for continuous renal replacement therapy in patients undergoing venovenous extracorporeal membrane oxygenation. [PDF]

J Thorac Dis
Xie J, Han L, Ouyang Y, Liu S, Liang Z, Xi Y, Chen X, Wang Y, Li J, Liu Y, He Y, Li J, Zhao L, Yang L, Lai W, Shang Y, Liu L, Liu X, Li Y, Xu Y.   +19 more
europepmc   +1 more source