Results 11 to 20 of about 6,033 (178)

Sympathetic Denervation Ameliorates Renal Fibrosis via Inhibition of Cellular Senescence

Frontiers in Immunology, 2022
ObjectiveContinuous overactivation of the renal sympathetic nerve is considered to be an important cause of renal fibrosis. Accumulated senescent cells in the damaged kidney have metabolic activities and secrete amounts of proinflammatory factors as part
Qian Li, Yuanjun Deng, Lele Liu, Chunjiang Zhang, Yang Cai, Tianjing Zhang, Min Han, Gang Xu   +7 more
doaj   +1 more source

Device-based approaches for renal nerve ablation for hypertension and beyond

Frontiers in Physiology, 2015
Animal and human studies have demonstrated that chronic activation of renal sympathetic nerves is critical in the pathogenesis and perpetuation of treatment-resistant hypertension.
Alicia Ann Thorp, Markus Peter Schlaich, Markus Peter Schlaich   +2 more
doaj   +1 more source

Comparison of Long‐Term Outcomes for Responders Versus Non‐Responders Following Renal Denervation in Resistant Hypertension

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Recent trial results support the efficacy of renal sympathetic denervation in lowering blood pressure (BP). While BP reduction in general is associated with a clinically meaningful reduction in cardiovascular events and mortality, such a ...
Karl Fengler, Paul Reimann, Karl‐Philipp Rommel, Karl‐Patrik Kresoja, Stephan Blazek, Matthias Unterhuber, Christian Besler, Maximilian von Roeder, Michael Böhm, Steffen Desch, Holger Thiele, Philipp Lurz   +11 more
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Renal sympathetic denervation: A promising therapy for resistant hypertension

Heart India, 2014
Despite rapid strides in pharmacotherapy for hypertension over last few decades, resistant hypertension continues to be prevalent. Activation of the sympathetic nervous system is an important etiological factor in the pathogenesis of hypertension and ...
Deepak Ameta, Akshyaya Kumar Pradhan, Rishi Sethi   +2 more
doaj   +1 more source

Renal Denervation Reduced Ventricular Arrhythmia After Myocardial Infarction by Inhibiting Sympathetic Activity and Remodeling

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Ventricular arrhythmia after myocardial infarction is the most important risk factor for sudden cardiac death, which poses a serious threat to human health.
Wen‐hui Zhang, Qi‐na Zhou, Yan‐mei Lu, Yao‐dong Li, Ling Zhang, Jiang‐hua Zhang, Qiang Xing, Wen‐kui Lv, Xin‐chun Cheng, Ge‐ge Zhang, Xue‐sheng Wang, Qi Gu, Xue Lou, Buajier Guli, Bao‐peng Tang, Xian‐hui Zhou   +15 more
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Renal Sympathetic Vasomotion Monitoring as a Novel Method for Intraprocedural Feedback for Renal Denervation

Graduate Medical Education Research Journal, 2019
Mentor: Irving H. Zucker Program: Anesthesiology Background & Objectives: The sympathetic nervous system is a master regulator of homeostasis, and sympathetic dysfunction is implicated in the pathophysiology of cardiovascular, renal, and neurological ...
Peter Ricci Pellegrino, Alicia M. Schiller, Han-jun Wang, Yiannis S. Chatzizisis, Irving H. Zucker   +4 more
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Selective ablation of the ligament of Marshall reduces ischemia and reperfusion-induced ventricular arrhythmias. [PDF]

PLoS ONE, 2018
Cardiac sympathetic tone overdrive is a key mechanism of arrhythmia. Cardiac sympathetic nerves denervation, such as LSG ablation or renal sympathetic denervation, suppressed both the prevalence of VAs and the incidence of SCD.
Ruisong Ma, Zhiliang Qin, Xiaomei Yu, Shan Liu, Weiyi Qu, Huihui Hu, Da Luo, Zhibing Lu, Hong Jiang   +8 more
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Pulse Wave Velocity Predicts Response to Renal Denervation in Isolated Systolic Hypertension

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
Background Renal sympathetic denervation seems to be less effective as a treatment for hypertension in patients with isolated systolic hypertension, a condition associated with elevated central arterial stiffness.
Karl Fengler, Karl‐Philipp Rommel, Robert Hoellriegel, Stephan Blazek, Christian Besler, Steffen Desch, Gerhard Schuler, Axel Linke, Philipp Lurz   +8 more
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Successful accessory renal artery denervation in a patient with resistant hypertension

Heart Views, 2014
Renal sympathetic denervation is safe and effective in patients with resistant hypertension. In all of the studies of renal artery denervation, patients with accessory renal arteries are excluded.
Halil Atas, Erdal Durmus, Murat Sunbul, Bulent Mutlu   +3 more
doaj   +1 more source

The Role of the Superior Cervical Sympathetic Ganglion in Ischemia Reperfusion-Induced Acute Kidney Injury in Rats

Frontiers in Medicine, 2022
Acute kidney injury (AKI) has been found to be a serious clinical problem with high morbidity and mortality, and is associated with acute inflammatory response and sympathetic activation that subsequently play an important role in the development of AKI.
Wencui Zhang, Zhen Li, Zhixiao Li, Tianning Sun, Zhigang He, Anne Manyande, Weiguo Xu, Hongbing Xiang   +7 more
doaj   +1 more source