Results 101 to 110 of about 944,625 (256)
UDP‐Glucose‐6‐Dehydrogenase Mediated O‐GlcNAcylation of Tight Junction Protein 1 Suppresses Metastasis in Renal Cell Carcinoma
Advanced Science, EarlyView.Our research unveiled a regulatory paradigm wherein TRIM25 orchestrates the ubiquitin‐mediated degradation of UGDH. UGDH modulates the protein stability of TJP1 by regulating O‐GlcNAcylation levels, effectively impeding the metastasis of ccRCC. Our insights elevate UGDH to a pivotal biomarker and tumor suppressor, marking the first demonstration that ...Xiaolin Chen, Yuhang Bao, Tao Liu, Jianhui Qiu, Yuanyuan Ma, Zedan Zhang, Chuandong Wang, Ruiyi Deng, Zheng Song, Tianyi He, Haode Liu, Jingcheng Zhou, Yizhou Wang, Kan Gong +13 morewiley +1 more sourceThe Mind From Within: Visceral Roots of Human Cognition
Advanced Science, EarlyView.The physiological activity of visceral organs, such as the heart, the lungs, and the gut, is surprisingly linked to many sophisticated mental operations, such as remembering the past, being aware of ourselves, making choices, and forging social bonds.Alessandro Monti, Salvatore Maria Aglioti +1 morewiley +1 more sourceThe ERA-EDTA cohort study—comparison of methods to predict survival on renal replacement therapy [PDF]
, 1997 Accurate prediction of patient survival from the time of starting renal replacement therapy (RRT) is desirable, but previously published predictive models have low accuracy.Castelluccia, N., SHIMIZU, Maria Heloisa Massola, MOYSES, Zenaide P., NAHAS, William C., Ricardo Magistroni, MAGISTRONI, Riccardo, Albertazzi, Alberto, Douglas-Denton, Rebecca, KANASHIRO, Hideki, LIMA, Jose Jayme Galvao De, DAVID, Daisa S. R., José Eduardo Krieger, Sakkas, G K, Ricardo Sesso, S. A. Draibe, LOBO, Julie Calixto, Silva, Antonio Carlos [UNIFESP], Uchino S, DELLE, Humberto, Zijlstra, Jan G.; id_orcid, Mooney, Michael, van der Laan, E., Galante, Nelson Z. [UNIFESP], Toorians, A.W.F.T., Jackson, Andrew J, BARROS, Silvana de, COSTA, Roberto Silva, Miname, Marcio H., Morgera S, Simpson, Keith, Avesani, Carla Maria [UNIFESP], Lindup, H., Taylor, K. J., Macdougall, Iain, SEGURO, Antonio Carlos, Jager, Kitty J., OLIVEIRA, Rodrigo A., Piccoli G. B., Carvalho, Aluizio B. [UNIFESP], Cano, N., Giltay, E. J., Tolfrey, K, Macdougall, I. C., RODRIGUES, Helcio, Jancikic, Alessandra D. B. [UNIFESP], Vigotti, Federica Neve, DAHER, Elizabeth F., J. Encke, van Meurs, Matijs, R. N. Douglas-Denton, Franchini Ramires, Jose Antonio, VIEIRA, Eduardo F., Alves da Silva, Cleonice Giovanini, Cuppari, L., Thao Nguyen-Khoa, Nunes, Ane Claudia Fernandes, Barber, William Henry, Kingsmore, David, A. Oliveira de Lima, C. M. Avesani, Moro I., Manfredi, Silvia R. [UNIFESP], Schetz M, Mercer, Thomas H, PASSLICK-DEETJEN, Jutta, Di Giorgio G., Alves, Maria Almerinda R., M. D. Hughson, Kurniati, Neng F., Frimat, L., Kellum JA, PASCHOAL, Juliana de Paiva, P. Inigo, M. McEvoy, Kingsmore, D.B., Mercer, Tom, MOYSES, Zenaide Providello, Kingsmore, David B., Silva, AC, Schanstra, Joost, P., Metcalfe, Wendy, Hoy, Wendy, Karatzaferi, Christina, SILVA, Cleonice Giovanini Alves da, Jochmans, Ina, Avesani, C.M., Westra, Johanna, Lilian Cuppari, Michael D. Hughson, FERREIRA, Gustavo F., YU, Luis, Leuvenink, Henri G. D., Vandijk, P., IANHEZ, Luiz E., Barbero, Silvia, Draibe, Sergio Antonio [UNIFESP], Moyses, Rosa M. A., Tolwani, Ashita, Viera Neto, Osvaldo M., Naish, P F, T. Samuel, Fouque, D, Toorians, A. W., Macedo E, Betonico, Gustavo N., Oe, P. L., Plauth, M., Castelluccia N., Ball, Derek, Drueeke, Tilman B., BASTOS, Ana Paula Almeida, Barros, Rui T., Fouque, Denis, Ajzen, Sergio A [UNIFESP], Clari, R., Avesani, Carla Maria, Ferraresi, M., Molema, Grietje, SAITO, Fernando, Ammirati, Adriano [UNIFESP], Gomes, Rui Alberto, Magalhaes, Andrea O., R. A. Gomes, Plauth, M, Naish, P. F., ANTONIO, Sergio R. De, BOIM, Mirian Aparecida, Reis, Luciene M. dos, Alexandre Costa Pereira, A. Ingsathit, Jackson, A.J., Kamimura, Maria Ayako [UNIFESP], Oudemans-van Straaten, Heleen M., Attia, John, CASTRO, Margaret De, Colombi N., Rebecca N. Douglas-denton, Maizel, Julien, Lindup, Herolin, NAHAS, Willian C., David R. W. Jayne, Mercer, Thomas H., Metcalfe, W., Suassuna, Paulo [UNIFESP], Toorians, A.W., MARTINS, Alice Maria Costa, Marrocos, Mauro S. M., Gibney, Noel, Kerr, Peter, Sergio Antonio Draibe, dos Reis, Luciene Machado, Oudemans-van Straaten, Heleen, Giltay, E.J., Pisoni, Ron L., Mello, Marco Tulio de [UNIFESP], Bergamo, Ronaldo R., Heimbürger, O., Oliveira, Ivone Braga de, K. M. Chow, Janssen, E., Sanches, Fabiana M. R. [UNIFESP], NAKANDAKARI, Fausto Kigui, PIOVESAN, Afonso Celso, Medina-Pestana, Jose O. [UNIFESP], CESAR, Luiz Antonio Machado, SILVA, Geraldo B., AC Pereira, Cuppari, L, Piccoli Giorgina Barbara, M. E. F. Canziani, Baria, Flavia [UNIFESP], Karatzaferi, C., Sens, Yvoty A. S., Mercer, T.H., Zimanyi, Monika A., VELARDE, Luis Guillermo Coca, David B. Kingsmore, Morgera, Stanislo, Lemos, Marcelo Montebello [UNIFESP], Morimatsu H, TV Pereira, Simpson, K.H., Hammes, Hans-Peter, Pascal, C., Kingsmore, David B, MOYSES, Rosa Maria Affonso, Frimat, Luc, Sargeant, Anthony J., ARNONI, Carine Prisco, Galvao De Lima, Jose Jayme, MAGALDI, Antonio J., Magistroni, Ricardo, Trevillian, Paul, Sardenberg, Camila [UNIFESP], M. Gerbase-DeLima, Inigo, Pablo, Kamimura, M.A., Dirce Maria Sigulem, Dalboni, Maria Aparecida [UNIFESP], Manfredi, Sílvia Regina [UNIFESP], KELLUM, John A., KFOURI, Flavia, Chan, M., ABENSUR, Henry, Macedo, Etienne, Deléaval, P., Tolfrey, K., Gerbase-DeLima, Maria [UNIFESP], Briançon, Serge, Jacquelinet, Christian, V. G. Puelles, Deleaval, Patrik, TESTAGROSSA, Leonardo, Mastroianni-Kirsztajn, Gianna, Armitage, James, Combe, Christian, McArthur, Stephen, McKenzie, J., RAMIRES, Jose Antonio Franchini, Pestana, Jose Osmar Medina [UNIFESP], M. Rudnicki, Krieger, Jose Eduardo [UNIFESP], Teta, D, JORGE, Lecticia B., MORGERA, Stanislao, Faxen-Irving, Gerd, Briançon, S., Herpe, Yves-Edouard, Bagshaw, Sean, Zwinderman, Aeilko H., Laan, E., John F. Bertram, Moser, Jill, Donker, A. J., Tiago Veiga Pereira, Fox, J., Colombi, N., Christofalo, Dejaldo M. [UNIFESP], Schanstra, J., S. Dmitrienko, Di Giorgio, G., S. Kesrouani, Wolff Gowdak, Luis Henrique, Deleuze, Jean-François, Puelles, Victor G., SOUZA, Patricia S., Zwiers, Peter J.; id_orcid, Rush, Robert, BAGSHAW, Sean M., SANTOS, Felipe Rizzetto, Stengel, Bénédicte, Zimanyi, Monika, Ferraresi, Martina, Santos, Oscar Pavão dos [UNIFESP], Bouman, Catherine, Sakkas, G.K., Sigulem, Dirce Maria [UNIFESP], Monbaliu, Diethard, Piccoli, G.B., Robinson, Bruce M, J. F. Bertram, Jacquelinet, C., Lima, Altair Oliveira de, Batista, Daniella Guimarães, Sakkas, Giorgos K., MAGALDI, Antonio Jose, Alberto Albertazzi, Koufaki, P., Zijlstra, Jan G., CASTRO, Maria Cristina R., Sakkas, G. K., Neves, Katia R., de Mutsert, R, Azar, R., J. Cruz, Cendoroglo, M, Malafronte, Patricia, Joki, Nobuhiko, Kesrouani, Silvana, Massy, Ziad A., A. Thakkinstian, Hawlitschek, Philippe, GINANI, Giordano F., Naif, PF, Tan, Ian, DAVID-NETO, Elias, Donker, A.J., LIBORIO, Alexandre Braga, Custodio, Melani R., Chow, Kai Ming, Gooren, L.J., Bertram, John, Arnoni, Carine Prisco [UNIFESP], Greenwood, S., Cano, N, Gooren, L. J., Hoy, Wendy E., Nikolov, Igor G., Sargeant, A.J., Bellomo R, Teta, Daniel, Pinto, SWL, Moro, I., ABDALLA, Dulcineia Saes Parra, Chauveau, P., Cuppari, Lilian [UNIFESP], W. H. Barber, Neves, Carolina L., Naish, P.F., FALCI JR., Renato, Rudnicki, Martina, Cruz D, KAROHL, Cristina, Heimbuerger, Olof, GOWDAK, Luis Henrique Wolff, Maria Koukoulaki, Taylor, K J, FRANCESCATO, Heloisa Della Coletta, Kirsztajn, Gianna Mastroianni [UNIFESP], Massy, Ziad A, Decuypere, Jean-Paul, Boim, Mirian Aparecida [UNIFESP], Fouque, D., Avesani, Carla M. [UNIFESP], JE Krieger, Kallas, Esper Georges [UNIFESP], V. G. Puelles, vom Hagen, Franziska, Guerrera, Ida Chiara, Heeringa, Peter, M. A. Dalboni, VIEIRA JR., Jose Mauro, McEvoy, Mark, BARREIRA, Andre Luis, Avesani, CM, Kenneth G. C. Smith, Sesso, R, Gansevoort, Ron T., ORTEGA, Katia Coelho, Greenwood, Sharlene A., ELIAS, Rosilene Motta, Cochrane Renal Grp Prospective Tri, Nazha, Marta, Sargeant, A J, Teta, D., Nazha M., Bagshaw SM, Pirenne, Jacques, Douglas-Denton, Rebecca N., Ribeiro de Moura, Luiz Antonio [UNIFESP], Aoike, Danilo Takashi [UNIFESP], LIBORIO, Alexandre B., CUNHA, Fernando Queiroz, BRAGANCA, Ana C. de, Antonio Carlos Silva, SOUZA, Clodoaldo J., Jager, K., McKenzie, Jane, DANILOVIC, Alexandre, Wendy E. Hoy, Moser, Jill; id_orcid, S. R. Manfredi, J. A. Armitage, Miguel Cendoroglo, ANDRADE, Lucia, Cadaval, Ricardo A. M., Morimatsu, Hiroshi, Douverny, Joao Batista [UNIFESP], Van Erp, Anne C., Paul Coats, Monika A. Zimanyi, Bellomo, Rinaldo, Geddes, Colin C., Martina Rudnicki, SALDANHA, Luiz B., VOLPINI, Rildo A., Benchitrit, Joyce, Edelman, Aleksander, Zwinderman, A., Coats, P., Carvalho, Maria Fernanda, Chan, Maria, McArthur, S.D.J., L. Cuppari, Pereira, Alexandre Costa, de Mutsert, R., Sargeant, Anthony J, Donker, A.J.M., Tolfrey, Keith, Greenwood, S, Dominguez, Wagner V., Bazanelli, Ana Paula [UNIFESP], Oe, P.L., Ball, D., Molema, Grietje; id_orcid, Trolonge, S., Gibney N, Pereno, Amina, Trolonge, Stanislas, ABENSUR, Hugo, McDaniel, D. Olga, Lacour, Bernard, Baria, F., STRAATEN, Heleen M. Oudemans-van, Naif, P. F., Stengel, B., Santos, Raul D., LEITE JR., Maurilo, Azar, R, Hallan, Stein I., Koufaki, Pelagia, Hughson, Michael D., Oudemans-van Straaten HM, Fachini, Fernando C., Jorgetti, Vanda, Puelles Rodriguez, Victor, SANCHES, Talita R. C., Laan, E. van der, P. G. Kerr, Koike, Marcia Kiyomi, Taylor, Kevin, Kerr, Peter G., Puelles, Victor, Woronik, Viktoria, Andrew J. Jackson, Canziani, Maria Eugenia F. [UNIFESP], Naish, Patrick F., Uchino, Shigehiko, Pascal, Christophe, Sargeant, A. J., Struys, Michel M. R. F.; id_orcid, Ottens, Petra J., Jongman, Rianne M., Kidney BEST Investigators, Canziani, Maria Eugenia Fernandes [UNIFESP], Jackson, Andrew, Cruz, Jenner, Fox, Jonathan G., SABER, Luciana T. S., Rocha, Mariana Leister [UNIFESP], Lindup, H, Egidio Romao, Joao, Cendoroglo Neto, Miguel [UNIFESP], P. Trevillian, Combe, C., SILVA, Ana Maria Goncalves da, Thakkinstian, Ammarin, Herpe, Y.-E., Ane Cláudia Fernandes Nunes, BARBOSA JUNIOR, Fernando, Dmitrienko, Svetlana, AC Nunes, Mooney, M., Ingsathit, Atiporn, Coats, Paul, Bortolotto, Luiz A., OLIVEIRA, Rodrigo Azevedo de, Rebolledo, Rolando, Karatzaferi, C, Baptista-Silva, Jose Carlos [UNIFESP], Sesso, Ricardo [UNIFESP], Graciolli, Fabiana Giorgeti, W. E. Hoy, Pereira, Tiago da Veiga [UNIFESP], Andreoli, Maria Claudia Cruz [UNIFESP], Mastroianni-Kirsztajn, Gianna [UNIFESP], Canziani, Maria E. F. [UNIFESP], Carla Maria Avesani, ANTONOPOULOS, Ioannis M., CASTRO, Isae de, Schanstra, Joost,, Naish, Patrick F, G. Mastroianni-Kirsztajn, Tolwani A, J. Attia, Heeringa, Peter; id_orcid, MOTA, Rosa M. S., M. A. Kamimura, Struys, Michel M. R. F., ARANTES, Rodolfo Leite, Robinson, B., Samuel, Terence, Polito, Maria Goretti [UNIFESP], Chauveau, Phillipe, PAULA, Flavio Jota de, Clari R., Massy, Z., Ferraresi M., Sumith C. Abeygunasekara, Ronco C, Faxén-Irving, G., Tan I, MION JR., Decio, Mafra, D., M. A. Zimanyi, CHRIGUER, Rosangela S., Geddes, C.D., Cruz, Dinna, Everaerd, W., Kellum, John, van Dijk, Paul C. W., ROMAO JR., Joao Egidio, Draibe, SA, Watanabe, Renato [UNIFESP], Ronco, Claudio, Srougi, Miguel, Hughson, Michael, M. Cendoroglo, Schetz, Miet, Dib, Gustavo A. [UNIFESP], de Paula, Flavio Jota, Pisoni, R., Cendoroglo, Miguel [UNIFESP], Armitage, James A., D. O. McDaniel, Macdougall, I C, Jackson, Andrew J., Zwiers, Peter J., KRIEGER, Eduardo M., Bouman C, Sigulem, DM, Nazha, M., Bertram, John F., COIMBRA, Terezila Machado, SILVA, Giovanio Vieira da, MAFRA, Denise, CASTRO, Manuel Carlos Martins de, Gooren, L.J.G., Laville, M., Sakkas, Giorgos K, GROSSO, Daniela de Mattos, Pappalardo, F., Kellum, John A (Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Investigators) +532 morecore +7 more sourcesUltrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis
Advanced Science, EarlyView.An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT
The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh +9 morewiley +1 more sourceUltra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization
Advanced Science, EarlyView.Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma +10 morewiley +1 more source
