Results 101 to 110 of about 2,503,709 (341)

Donation after brain death followed by circulatory death, a novel donation pattern, confers comparable renal allograft outcomes with donation after brain death

BMC Nephrology, 2018
Background Organ donation after brain death (DBD) is the standard strategy for organ transplantation; however, the concept of brain death is not universally accepted due to cultural beliefs and barriers amongst billions of people worldwide.
Qipeng Sun, Honglan Zhou, Ronghua Cao, Minzhuan Lin, Xuefeng Hua, Liangqing Hong, Zhengyu Huang, Ning Na, Ruiming Cai, Gang Wang, Fanhang Meng, Qiquan Sun   +11 more
doaj   +1 more source

High-immunological risk living donor renal transplant during the COVID-19 outbreak: Uncertainties and ethical dilemmas [PDF]

, 2020
Quan Yao Ho, Shimin Jasmine Chung, Valerie Huei Li Gan, Lay Guat Ng, Ban Hock Tan, Terence Kee   +5 more
openalex   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

NAD+‐Dependent Enzyme SIRT3 Limits Intestinal Epithelial Cell Functions Through NAD+ Synthesis Pathway in Colorectal Cancer

Advanced Science, EarlyView.
Microbiota‐derived quinolinic acid is used as an alternative source of replenishing the intracellular NAD+ pool induced by SIRT3 deficiency to regulate intestinal epithelial cell and T cell function, which has implications for targeting intestinal epithelial cells as an approach to the treatment of immune‐associated diseases, including colorectal ...
Ruiying Niu, Yingjie Dong, Jianghui Tong, Jingxuan Xia, Longhao Zhao, Zi Geng, Yingxin Lin, Jinghe Zhang, Xinyi Liu, Manqi Fang, Xi Jin, Yujing Bi, Guangwei Liu   +12 more
wiley   +1 more source

Tacrolimus rescue therapy for renal allograft rejection - Five-year experience [PDF]

, 1997
Over the 5 year period from 7/14/1989 until 5/24/1994, we have attempted graft salvage with tacrolimus conversion in a total of 169 patients (median age 33 years, range 2-75 years) with ongoing rejection on baseline CsA immunosuppression after failure of
Demetris, AJ, Fung, JJ, Gritsch, HA, Jordan, ML, McCauley, J, McMichael, J, Naraghi, R, Randhawa, P, Scantlebury, VP, Shapiro, R, Smith, D, Starzl, TE, Vivas, CA   +12 more
core   +1 more source

Multiple Arteries in the Renal Transplant [PDF]

, 2022
Cavoli Gioacchino Li, Matranga Saverio, Andrea Macaluso, Antonio Amato, Vitalba Azzolina, Angelo Tralongo   +5 more
openalex   +1 more source

PBRM1 Deficiency Reshapes an Immune Suppressive Microenvironment Through Epigenetic Tuning of PBRM1‐KDM5C‐IL6 Axis in ccRCC

Advanced Science, EarlyView.
PBRM1 ranks as the second most commonly mutated gene in ccRCC. This study reveals that PBRM1 loss promotes an immunosuppressive microenvironment by elevating M2 TAMs via the KDM5C–IL‐6 axis. These M2 TAMs, along with CAFs, form a barrier that excludes CD8+ T cells. Targeting IL‐6 synergizes with anti‐PD1 therapy, offering a promising strategy for PBRM1‐
Wenjiao Xia, Hongru Wang, Yu Dong, Zitong Yang, Yiyang Zhou, Zhinan Xia, Qinchen Li, Liangliang Ren, Yichun Zheng, Junliang Yan, Dongmei Ma, Zhi Chen, Xingang Cui, Guixin Zhu, Cheng Zhang   +14 more
wiley   +1 more source

Xanthogranulomatous Pyelonephritis with Incomplete Double Ureter

Case Reports in Medicine, 2017
Introduction. Xanthogranulomatous pyelonephritis (XGP) is a type of chronic renal inflammation that usually occurs in immunocompromised middle-aged women with chronic urinary tract infection or ureteral obstruction induced by the formation of ureteral ...
Yutaro Hayashi, Takashi Kawahara, Yusuke Hattori, Kota Shimokihara, Sohgo Tsutsumi, Daiji Takamoto, Taku Mochizuki, Jun-ichi Teranishi, Yasushi Yumura, Yasuhide Miyoshi, Masako Otani, Hiroji Uemura   +11 more
doaj   +1 more source

Improvement of polyuria, bladder sensation and bladder capacity following renal transplantation [PDF]

, 2006
Hiroya Mizusawa, Osamu Ishizuka, Yasuhiko Igawa, Motokiyo Komiyama, Kyoko Irie, Kenji Iwata, Osamu Nishizawa   +6 more
openalex   +1 more source

AB1042 PEGLOTICASE USE IN RENAL TRANSPLANT RECIPIENTS WITH GOUT: AN INSURANCE CLAIMS STUDY [PDF]

, 2022
Craig Alan Shadur, Brad A. Marder, C. Vesel, Brian LaMoreaux   +3 more
openalex   +1 more source