Results 81 to 90 of about 1,138,097 (292)

Renal impairment in a rural African antiretroviral programme [PDF]

, 2009
Background: There is little knowledge regarding the prevalence and nature of renal impairment in African populations initiating antiretroviral treatment, nor evidence to inform the most cost effective methods of screening for renal impairment.
Till Barnighausen, Cooke, GS, Barnighausen, Till, Cara Franey, Lessells, RJ, Newell, Marie-Louise, Knott, Deborah, Franey, C, Dedicoat Martin, Dedicoat, Martin, Newell Marie-Louise, Adam, A, Deborah Knott, Martin Dedicoat, Knott, D, Adam, Ahmed, Ahmed Adam, Newell, M-L, Franey, Cara, Lessells Richard J, Adam Ahmed, Richard J Lessells, Cooke Graham S, Marie-Louise Newell, Cooke, Graham S, Barnighausen Till, Lessells, Richard J, Dedicoat, M, Graham S Cooke, Knott Deborah, Barnighausen, T, Franey Cara   +31 more
core   +2 more sources

The neutrophil-to-lymphocyte ratio (NLR) predicts adrenocortical carcinoma and is correlated with the prognosis

BMC Urology, 2017
Background The neutrophil-to-lymphocyte ratio (NLR) is reported as a biomarker for some solid malignant diseases. Thus far, however, no reports of the relationship between the NLR and adrenal tumors have been published.
Taku Mochizuki, Takashi Kawahara, Daiji Takamoto, Kazuhide Makiyama, Yusuke Hattori, Jun-ichi Teranishi, Yasuhide Miyoshi, Yasushi Yumura, Masahiro Yao, Hiroji Uemura   +9 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

UDP‐Glucose‐6‐Dehydrogenase Mediated O‐GlcNAcylation of Tight Junction Protein 1 Suppresses Metastasis in Renal Cell Carcinoma

Advanced Science, EarlyView.
Our research unveiled a regulatory paradigm wherein TRIM25 orchestrates the ubiquitin‐mediated degradation of UGDH. UGDH modulates the protein stability of TJP1 by regulating O‐GlcNAcylation levels, effectively impeding the metastasis of ccRCC. Our insights elevate UGDH to a pivotal biomarker and tumor suppressor, marking the first demonstration that ...
Xiaolin Chen, Yuhang Bao, Tao Liu, Jianhui Qiu, Yuanyuan Ma, Zedan Zhang, Chuandong Wang, Ruiyi Deng, Zheng Song, Tianyi He, Haode Liu, Jingcheng Zhou, Yizhou Wang, Kan Gong   +13 more
wiley   +1 more source

Financial Barriers to Organ Transplantation: A Comparative Analysis [PDF]

, 2012
Organ procurement and transplantation is an expensive process. Because of economic concerns, hospitals often refuse to list otherwise qualified patients for transplant unless that patient has the financial means to pay for the transplant and related ...
Renkes, Ashley C
core  

Impact of citrate dialysate on middle molecular weight uremic toxin adsorption and removal in high-flux and MCO dialysis membranes

Scientific Reports
Hemodialysis treatment with bicarbonate requires a weak acid to prevent salt precipitation. Acetate is implemented in chronic hemodialysis while citrate is used in continuous treatments due to its anticoagulation properties, offering a plethora of ...
Miquel Gomez, Diana Rodriguez-Espinosa, Jose Jesus Broseta Monzo, Marta Arias-Guillen, Nestor Fontseré, Lida Rodas, Francisco Maduell   +6 more
doaj   +1 more source

The Mind From Within: Visceral Roots of Human Cognition

Advanced Science, EarlyView.
The physiological activity of visceral organs, such as the heart, the lungs, and the gut, is surprisingly linked to many sophisticated mental operations, such as remembering the past, being aware of ourselves, making choices, and forging social bonds.
Alessandro Monti, Salvatore Maria Aglioti   +1 more
wiley   +1 more source

Extended pancreas donor program - the EXPAND study rationale and study protocol [PDF]

, 2013
BACKGROUND: Simultaneous pancreas kidney transplantation (SPK), pancreas transplantation alone (PTA) or pancreas transplantation after kidney (PAK) are the only curative treatment options for patients with type 1 (juvenile) diabetes mellitus with or ...
Bechstein, Wolf Otto, Carsten Dietz, Falk Rauchfuss, Holub, Ines, Peter Schenker, Heise, Michael, Volker Müller, Rauchfuss, Falk, Proneth, Andrea, Florian Zeman, Björn Nashan, Markus Guba, Banas, Bernhard, Stefan Thorban, Schemmer, Peter, Edward K Geissler, Stephan Kersting, Ströhlein, Michael A., Andreas A Schnitzbauer, Nashan, Björn, Jonas, Sven, Thomas Becker, Ines Holub, Johanna R Foerster, Andreas Pascher, Manekeller, Steffen, Viebahn, Richard, Müller, Volker, Thomas Vogel, Peter Schemmer, Bernhard Banas, Farkas, Stefan A., Andrea Proneth, Arbogast, Helmut, Schenker, Peter, Richard Viebahn, Thorban, Stefan, Jürgen Klempnauer, Silvio Nadalin, Axel O Rahmel, Vogel, Thomas, Becker, Thomas, Guba, Markus, Zeman, Florian, Kersting, Stephan, Michael Heise, Rahmel, Axel, Klempnauer, Jürgen, Schlitt, Hans J., Schnitzbauer, Andreas, Stefan A Farkas, Nadalin, Silvio, Sven Jonas, Steffen Manekeller, Helmut Arbogast, Hans J Schlitt, Dietz, Carsten, Michael A Ströhlein, Geissler, Edward K., Wolf O Bechstein, Foerster, Johanna R., Pascher, Andreas, Andrea Proneth   +62 more
core   +1 more source

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source

[Renal transplantation - new developments]

, 2011
Renal transplantation has become an established option for renal replacement therapy in many patients with end stage renal disease. Living donation is a possibility for timely transplantation, hampered in 20 % of all possible donors and recipients ...
Eisenberger, Ute
core   +1 more source