Results 101 to 110 of about 209,491 (261)

Severe ADEM‐Like Neuroinflammatory Disease and Cerebrovascular Fragility With Recurrent Pseudoaneurysms and Moyamoya in a Familial Germline CBL Mutation: Expanding the Clinical Phenotype

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Heterozygous germline variants in CBL disrupt its function as a negative regulator of the Ras/MAPK pathway, classically predisposing to Juvenile myelomonocytic leukemia (JMML) and moyamoya. We describe two affected siblings carrying a paternally inherited CBL variant (c.1210 T> C, p.
Michal Bar‐Hakim, Anat Abramovich, Sara Via‐Dorembus, Gali Heimer, Bruria Ben‐Zeev, Etai Adam, Assaf A. Barg, Jonathan Roth, Basheer Sheick‐Yousif, Rony Beeri Berkowiz, Michal Feldon, Haim Bassan, Moran Hausman‐Kedem   +12 more
wiley   +1 more source

WCN24-909 ARTERIAL HYPERTENSION (AH) IN RENAL TRANSPLANT RECIPIENTS (RT) RISK FACTORS AND INPACT

Kidney International Reports
Ndiaga Sow, Wissal Sahtout, Awatef Azzabi, Yosra Zmanter, Sanda Mrabet, Rihem Dahmane, Ferdaous Sabri, Asma Fradi, Nesrine Thabet, Mehdi Slim, Olfa Mahfoud, Raja Boukadida, Yosra Guedri, Elias Neffeti, Narjes Ben Aicha, Dorsaf Zellama   +15 more
doaj   +1 more source

Porcine kidney xenotransplantation: From primate models to clinical reality

Animal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo, Ling Zhang, Shoulong Deng, Chuan Qin   +3 more
wiley   +1 more source

WCN25-1917 EXPANDING THE PHENOTYPIC SPECTRUM OF FABRY DISEASE: A CASE OF RENAL INVOLVEMENT IN A CARDIAC VARIANT

Kidney International Reports
Rihem Dahmane, Yosra Zmantar, Olfa Mahfoudh, Raja Boukadida, Nehed Ghenam, Roua Farhat, Narjes Ben Aicha, Wissal Sahtout, Yosra Guedri, Sanda Mrabet, Awatef Azzabi, Dorsaf Zellama   +11 more
doaj   +1 more source

Sickle Cell Disease and Kidney Injury: Circulating Uromodulin Allows Early Tissue Specific Diagnosis and Monitoring of Treatment

American Journal of Hematology, EarlyView.
Ferras Alashkar, Robert Hable, Denise Zwanziger, Friederike Poppenborg, Raina Yamamoto, Hans Christian Reinhardt, Alexander Röth, Victor Herbst, Yara Bestmann, Marco Kai, Jürgen E. Scherberich   +10 more
wiley   +1 more source

Stem cell–based therapies for type 1 diabetes: Progress in differentiation, clinical translation, and immune protection

Animal Models and Experimental Medicine, EarlyView.
Directed differentiation of pluripotent stem cells into functional pancreatic β cells have emerged as a promising strategy for the radical treatment of type 1 diabetes, with preclinical and early clinical evidence demonstrating reversal of hyperglycemia and insulin independence.
Zifan Li, Yu Kang, Yuyu Niu
wiley   +1 more source

WCN24-19 CYTOMEGALOVIRUS (CMV) INFECTIONS AFTER RENAL TRANSPLANTATION (RT): EXPERIENCE AT CHU SAHLOUL

Kidney International Reports
Ndiaga Sow, Wissal Sahtout, Awatef Azzabi, Raja Boukadida, Sanda Mrabet, Wafa Kallela, Ferdaous Sabri, Asma Fradi, Nesrine Thabet, Rihem Dahmane, Olfa Mahfoud, Samira Ben Amor, Yosra Guedri, Abdelhalim Trabelsi, Narjes Ben Aicha, Dorsaf Zellama   +15 more
doaj   +1 more source

Editorial: Renal fibrosis and renal transplantation. [PDF]

Front Immunol
Yang C.
europepmc   +1 more source

Humanized immune system animal models and their recent applications

Animal Models and Experimental Medicine, EarlyView.
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli, Rudra B. Amin, A’ishah Bakayoko, Marisa Kruidenier, Sahara Aqui, Sarah J. Skuli, Terence P. Gade   +6 more
wiley   +1 more source

Urobiome composition after renal transplantation: an exploratory study. [PDF]

BMC Microbiol
Harriman D, Ng A, Bronowski M, Yang R, Dang T, Sherwood K, Nguan C, Miller A, Lange D.   +8 more
europepmc   +1 more source